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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of fatty acid metabolic process
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Accession:GO:0045923 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
Synonyms:exact_synonym: positive regulation of fatty acid metabolism;   up regulation of fatty acid metabolic process;   upregulation of fatty acid metabolic process
 narrow_synonym: activation of fatty acid metabolic process;   stimulation of fatty acid metabolic process


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positive regulation of fatty acid metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
MGI:MGI:2387344 (MGI:MGI:2181851|PMID:12068289)
GO_REF:0000024
RGD
UniProt
PMID:12068289 GO_REF:0000024, MGI:MGI:2181851 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:12045256 RGD:625699 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
positive regulation of fatty acid beta-oxidation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO
ISS
(PMID:23123468)
GO_REF:0000024
(MGI:MGI:3835692|PMID:18854420), (MGI:MGI:3836690|PMID:18723473), (MGI:MGI:6189665|PMID:23123468)
RGD
UniProt
PMID:18723473, PMID:18854420, PMID:23123468 GO_REF:0000024, MGI:MGI:3835692, MGI:MGI:3836690, MGI:MGI:6189665 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:3835692|PMID:18854420), (MGI:MGI:3836690|PMID:18723473)
GO_REF:0000024
(PMID:10196381)
Ensembl
RGD
UniProt
PMID:10196381, PMID:18723473, PMID:18854420 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3835692, MGI:MGI:3836690 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 IGI RGD PMID:14711823 RGD:2312802 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO
IEA
(PMID:16814735)
GO_REF:0000107
RGD
Ensembl
PMID:16814735 GO_REF:0000107 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A IMP RGD PMID:19302064 RGD:2311346 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Fabp1 fatty acid binding protein 1 IDA peroxisomal RGD PMID:16262600 RGD:1626442 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Irs1 insulin receptor substrate 1 ISO
IEA
(PMID:16814735)
GO_REF:0000107
RGD
Ensembl
PMID:16814735 GO_REF:0000107 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 ISO (PMID:16814735) RGD PMID:16814735 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Plin5 perilipin 5 IDA
ISO
PMID:22127648
(MGI:MGI:3709110|PMID:17130488)
RGD PMID:17130488, PMID:22127648 MGI:MGI:3709110, RGD:8553692 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:20007935) RGD PMID:20007935 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
positive regulation of fatty acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO (MGI:MGI:2154640|PMID:11606482) RGD PMID:11606482 MGI:MGI:2154640 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Apoa1 apolipoprotein A1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 ISO
IBA
IEA
(PMID:2307668)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:2307668, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoa5 apolipoprotein A5 ISO
IBA
IEA
(PMID:18635818)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:18635818, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apoc2 apolipoprotein C2 ISO (PMID:10727238) RGD PMID:10727238 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IMP RGD PMID:16800817 RGD:1624995 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Ins2 insulin 2 ISO (PMID:14677856) RGD PMID:14677856 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 ISO (PMID:23749231) RGD PMID:23749231 NCBI chr13:110,397,353...110,470,874
Ensembl chr13:110,398,800...110,467,834
JBrowse link
G Mid1ip1 MID1 interacting protein 1 ISO
ISS
(MGI:MGI:4454592|PMID:20457939)
GO_REF:0000024
RGD
UniProt
PMID:20457939 GO_REF:0000024, MGI:MGI:4454592 NCBI chr  X:13,114,557...13,119,274
Ensembl chr  X:13,114,569...13,116,743
JBrowse link
G Mlxipl MLX interacting protein-like ISO (MGI:MGI:3041761|PMID:15118080) RGD PMID:15118080 MGI:MGI:3041761 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO (PMID:17186944) RGD PMID:17186944 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Rgn regucalcin IDA RGD PMID:16817230 RGD:9590221 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Slc45a3 solute carrier family 45, member 3 ISO (MGI:MGI:5464987|PMID:22521588) RGD PMID:22521588 MGI:MGI:5464987 NCBI chr13:48,745,855...48,766,283
Ensembl chr13:48,745,860...48,766,283
JBrowse link
positive regulation of fatty acid oxidation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf2 C1q and TNF related 2 ISO (MGI:MGI:3055459|PMID:15231994) RGD PMID:15231994 MGI:MGI:3055459 NCBI chr10:29,067,102...29,084,035
Ensembl chr10:29,067,102...29,084,035
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:23449193 RGD:10400846 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Mlycd malonyl-CoA decarboxylase ISO
IBA
ISS
(PMID:18314420)
PMID:21873635
GO_REF:0000024
(MGI:MGI:5501374|PMID:23746352)
RGD
UniProt
PMID:18314420, PMID:23746352, PMID:21873635 GO_REF:0000024, MGI:MGI:5501374, RGD:13792537 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO
ISS
(MGI:MGI:5645208|PMID:18325999)
GO_REF:0000024
RGD
UniProt
PMID:18325999 GO_REF:0000024, MGI:MGI:5645208 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nucb2 nucleobindin 2 IDA RGD PMID:21828181 RGD:9831189 NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO (MGI:MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:MGI:3526480 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IMP RGD PMID:19965574 RGD:2324877 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:18475159 RGD:2301882 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:16139565, PMID:23250358 RGD:1601466, RGD:7241851 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 NAS PMID:11997383 UniProt PMID:11997383 RGD:727370 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8260938, PMID:21873635 RGD:2306959, RGD:13792537 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Avp arginine vasopressin IMP RGD PMID:17254553 RGD:2300349 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:17254553 RGD:2300349 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Cd74 CD74 molecule ISO (PMID:24569872) RGD PMID:24569872 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Il1b interleukin 1 beta IEA
ISO
GO_REF:0000107
RNAcentral:URS0000424278_9606 (PMID:29384235)
Ensembl
RGD
PMID:29384235 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:9786861 RGD:2304243 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Pla2g3 phospholipase A2, group III ISO
IEA
(PMID:23624557)
GO_REF:0000107
(MGI:MGI:5492190|PMID:23624557)
RGD
Ensembl
PMID:23624557 GO_REF:0000107, MGI:MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Pla2g4a phospholipase A2 group IVA IMP RGD PMID:16203828 RGD:1642461 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO (MGI:MGI:5474549|PMID:21716255)
(PMID:21716255)
RGD PMID:21716255 MGI:MGI:5474549 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
positive regulation of unsaturated fatty acid biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO (MGI:MGI:3835692|PMID:18854420) RGD PMID:18854420 MGI:MGI:3835692 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISO
ISS
(MGI:MGI:3835692|PMID:18854420)
GO_REF:0000024
RGD
UniProt
PMID:18854420 GO_REF:0000024, MGI:MGI:3835692 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    positive regulation of biological process 6667
      positive regulation of cellular process 6147
        positive regulation of cellular metabolic process 3586
          positive regulation of fatty acid metabolic process 46
            positive regulation of butyryl-CoA catabolic process to butanol 0
            positive regulation of fatty acid biosynthetic process + 26
            positive regulation of fatty acid oxidation + 20
            positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
            positive regulation of prostaglandin catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      small molecule metabolic process 1870
        organic acid metabolic process 1090
          oxoacid metabolic process 1061
            carboxylic acid metabolic process 1005
              monocarboxylic acid metabolic process 665
                fatty acid metabolic process 423
                  regulation of fatty acid metabolic process 102
                    positive regulation of fatty acid metabolic process 46
                      positive regulation of butyryl-CoA catabolic process to butanol 0
                      positive regulation of fatty acid biosynthetic process + 26
                      positive regulation of fatty acid oxidation + 20
                      positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid 0
                      positive regulation of prostaglandin catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.