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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of natural killer cell mediated cytotoxicity
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Accession:GO:0045953 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
Synonyms:exact_synonym: down regulation of natural killer cell mediated cytotoxicity;   downregulation of natural killer cell mediated cytotoxicity;   negative regulation of NK cell mediated cell death;   negative regulation of NK cell mediated cell killing;   negative regulation of NK cell mediated cytotoxicity;   negative regulation of natural killer cell mediated cell death;   negative regulation of natural killer cell mediated cell killing
 narrow_synonym: inhibition of natural killer cell mediated cytotoxicity
 related_synonym: negative regulation of NK cell mediated cytolysis;   negative regulation of natural killer cell mediated cytolysis


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negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARRB2 arrestin beta 2 JBrowse link 17 4,710,619 4,721,500 RGD:2290271
G CLEC12B C-type lectin domain family 12 member B JBrowse link 12 10,006,138 10,018,800 RGD:2290271
G CRK CRK proto-oncogene, adaptor protein JBrowse link 17 1,420,693 1,456,232 RGD:2290271
G HLA-E major histocompatibility complex, class I, E JBrowse link 6 30,489,508 30,494,194 RGD:2290271
G HLA-F major histocompatibility complex, class I, F JBrowse link 6 29,723,340 29,740,355 RGD:2290271
G HLA-G major histocompatibility complex, class I, G JBrowse link 6 29,826,979 29,831,130 RGD:2290271
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 JBrowse link 19 54,803,610 54,814,517 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G MICA MHC class I polypeptide-related sequence A JBrowse link 6 31,400,711 31,415,315 RGD:2290271
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HLA-F major histocompatibility complex, class I, F JBrowse link 6 29,723,340 29,740,355 RGD:2290271
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 42,507,306 42,528,482 RGD:2290271
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 157,085,832 157,109,044 RGD:2290271
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HLA-A major histocompatibility complex, class I, A JBrowse link 6 29,942,532 29,945,870 RGD:2290271
G HLA-B major histocompatibility complex, class I, B JBrowse link 6 31,353,875 31,357,179 RGD:2290271
G HLA-E major histocompatibility complex, class I, E JBrowse link 6 30,489,508 30,494,194 RGD:2290271
G HLA-G major histocompatibility complex, class I, G JBrowse link 6 29,826,979 29,831,130 RGD:2290271
G SERPINB4 serpin family B member 4 JBrowse link 18 63,637,259 63,644,310 RGD:2290271
G SERPINB9 serpin family B member 9 JBrowse link 6 2,887,270 2,903,318 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18019
    cellular process 16998
      negative regulation of cellular process 5001
        negative regulation of cell killing 24
          negative regulation of leukocyte mediated cytotoxicity 20
            negative regulation of natural killer cell mediated cytotoxicity 16
              negative regulation of natural killer cell degranulation 1
              negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2
              protection from natural killer cell mediated cytotoxicity 6
Path 2
Term Annotations click to browse term
  biological_process 18019
    response to stimulus 9491
      response to external stimulus 2907
        response to external biotic stimulus 1551
          response to other organism 1549
            defense response to other organism 1197
              innate immune response 975
                natural killer cell mediated immunity 67
                  regulation of natural killer cell mediated immunity 45
                    negative regulation of natural killer cell mediated immunity 17
                      negative regulation of natural killer cell mediated cytotoxicity 16
                        negative regulation of natural killer cell degranulation 1
                        negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2
                        protection from natural killer cell mediated cytotoxicity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.