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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of natural killer cell mediated cytotoxicity
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Accession:GO:0045953 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
Synonyms:exact_synonym: down regulation of natural killer cell mediated cytotoxicity;   downregulation of natural killer cell mediated cytotoxicity;   negative regulation of NK cell mediated cell death;   negative regulation of NK cell mediated cell killing;   negative regulation of NK cell mediated cytotoxicity;   negative regulation of natural killer cell mediated cell death;   negative regulation of natural killer cell mediated cell killing
 narrow_synonym: inhibition of natural killer cell mediated cytotoxicity
 related_synonym: negative regulation of NK cell mediated cytolysis;   negative regulation of natural killer cell mediated cytolysis


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negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
G Clec12b C-type lectin domain family 12, member B JBrowse link 4 163,140,883 163,157,996 RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:11568650
G Gfer growth factor, augmenter of liver regeneration JBrowse link 10 14,059,347 14,061,703 RGD:9685777
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:9685777
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Mill1 MHC I like leukocyte 1 JBrowse link 1 79,631,266 79,657,943 RGD:1624291
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313500
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
G Sh2d1b2 SH2 domain containing 1B2 JBrowse link 13 88,557,361 88,584,078 RGD:1624291
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Klre1 killer cell lectin-like receptor, family E, member 1 JBrowse link 4 163,346,684 163,355,050 RGD:1299590
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec2d C-type lectin domain family 2, member D JBrowse link 4 162,278,252 162,302,881 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
G Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A JBrowse link 13 27,153,500 27,159,319 RGD:1624291
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:2312378
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:2312378

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cell killing 204
      negative regulation of cell killing 30
        negative regulation of leukocyte mediated cytotoxicity 23
          negative regulation of natural killer cell mediated cytotoxicity 19
            negative regulation of natural killer cell degranulation 2
            negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3
            protection from natural killer cell mediated cytotoxicity 6
Path 2
Term Annotations click to browse term
  biological_process 19336
    response to stimulus 10395
      response to external stimulus 3062
        response to external biotic stimulus 1569
          response to other organism 1565
            defense response to other organism 984
              innate immune response 693
                natural killer cell mediated immunity 69
                  regulation of natural killer cell mediated immunity 53
                    negative regulation of natural killer cell mediated immunity 20
                      negative regulation of natural killer cell mediated cytotoxicity 19
                        negative regulation of natural killer cell degranulation 2
                        negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3
                        protection from natural killer cell mediated cytotoxicity 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.