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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of complement activation, classical pathway
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Accession:GO:0045959 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:exact_synonym: down regulation of complement activation, classical pathway;   downregulation of complement activation, classical pathway;   negative regulation of complement cascade, classical pathway
 narrow_synonym: inhibition of complement activation, classical pathway


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negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1624291
RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    immune system process 2611
      immune effector process 823
        complement activation 149
          complement activation, classical pathway 127
            negative regulation of complement activation, classical pathway 4
              negative regulation of complement activation, classical pathway in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        regulation of immune system process 1413
          negative regulation of immune system process 467
            negative regulation of immune effector process 139
              negative regulation of leukocyte mediated immunity 61
                negative regulation of lymphocyte mediated immunity 50
                  negative regulation of B cell mediated immunity 13
                    negative regulation of immunoglobulin mediated immune response 13
                      negative regulation of humoral immune response mediated by circulating immunoglobulin 7
                        negative regulation of complement activation, classical pathway 4
                          negative regulation of complement activation, classical pathway in other organism 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.