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ONTOLOGY REPORT - ANNOTATIONS


Term:nucleobase biosynthetic process
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Accession:GO:0046112 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
Synonyms:exact_synonym: nucleobase anabolism;   nucleobase biosynthesis;   nucleobase formation;   nucleobase synthesis


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'de novo' pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 6 26,657,507 26,680,459 RGD:5132591
RGD:13792537
RGD:1624291
G Cmpk1 cytidine/uridine monophosphate kinase 1 JBrowse link 5 133,759,722 133,786,452 RGD:1600115
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:1600115
G Dhodh dihydroorotate dehydrogenase (quinone) JBrowse link 19 42,066,103 42,087,906 RGD:5132591
RGD:13792537
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
RGD:1600115
G Umps uridine monophosphate synthetase JBrowse link 11 70,034,181 70,044,590 RGD:1600115
adenine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:1624291
RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:13792537
guanine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
RGD:13792537
G Prtfdc1 phosphoribosyl transferase domain containing 1 JBrowse link 17 87,926,242 88,037,040 RGD:1624291
hypoxanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G Prps1 phosphoribosyl pyrophosphate synthetase 1 JBrowse link X 111,798,233 111,820,270 RGD:1624291
hypoxanthine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
purine nucleobase biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase JBrowse link 11 31,780,477 31,805,728 RGD:1600115
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:13792537
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like JBrowse link 1 40,529,092 40,719,232 RGD:13792537
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
pyrimidine nucleobase biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctps1 CTP synthase 1 JBrowse link 5 139,475,934 139,505,065 RGD:13792537
G Ctps2 CTP synthase 2 JBrowse link X 33,383,087 33,522,852 RGD:13792537
G Umps uridine monophosphate synthetase JBrowse link 11 70,034,181 70,044,590 RGD:13792537
xanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        organonitrogen compound metabolic process 6369
          nucleobase metabolic process 49
            nucleobase biosynthetic process 19
              purine nucleobase biosynthetic process + 11
              pyrimidine nucleobase biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 18008
    cellular process 16139
      cellular metabolic process 9809
        cellular nitrogen compound metabolic process 5698
          nucleobase-containing compound metabolic process 4896
            nucleobase-containing small molecule metabolic process 535
              nucleobase metabolic process 49
                nucleobase biosynthetic process 19
                  purine nucleobase biosynthetic process + 11
                  pyrimidine nucleobase biosynthetic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.