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ONTOLOGY REPORT - ANNOTATIONS


Term:pigment biosynthetic process
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Accession:GO:0046148 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
Synonyms:exact_synonym: pigment anabolism;   pigment biosynthesis;   pigment formation;   pigment synthesis


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pigment biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
adenine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase JBrowse link 11 31,780,477 31,805,728 RGD:13792537
adenine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:1624291
RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:13792537
guanine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:13792537
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
RGD:13792537
G Prtfdc1 phosphoribosyl transferase domain containing 1 JBrowse link 17 87,926,242 88,037,040 RGD:1624291
heme A biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 JBrowse link 10 50,439,778 50,563,920 RGD:1624291
G Cox15 cytochrome c oxidase assembly homolog COX15 JBrowse link 1 263,494,850 263,511,510 RGD:1624291
RGD:13792537
heme biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:1599020
RGD:13792537
RGD:1624291
RGD:1600115
G Alas1 5'-aminolevulinate synthase 1 JBrowse link 8 114,927,704 114,941,038 RGD:13792537
G Alas2 5'-aminolevulinate synthase 2 JBrowse link X 23,167,576 23,187,356 RGD:1624291
RGD:13792537
RGD:1600115
G Atp5if1 ATP synthase inhibitory factor subunit 1 JBrowse link 5 150,719,570 150,723,287 RGD:1624291
RGD:13792537
RGD:1600115
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 JBrowse link 10 50,439,778 50,563,920 RGD:13792537
G Cpox coproporphyrinogen oxidase JBrowse link 11 44,039,665 44,049,648 RGD:1600961
RGD:1624291
G Fech ferrochelatase JBrowse link 18 59,941,992 59,975,192 RGD:1600961
RGD:13792537
RGD:1624291
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1600115
G Hmbs hydroxymethylbilane synthase JBrowse link 8 48,667,278 48,674,673 RGD:13792537
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1624291
G Pgrmc1 progesterone receptor membrane component 1 JBrowse link X 123,205,869 123,213,880 RGD:1600115
RGD:1624291
G Ppox protoporphyrinogen oxidase JBrowse link 13 89,650,094 89,654,998 RGD:1600961
RGD:13792537
RGD:1624291
G Slc11a2 solute carrier family 11 member 2 JBrowse link 7 142,025,812 142,062,892 RGD:1624291
RGD:1600115
G Slc25a39 solute carrier family 25, member 39 JBrowse link 10 90,351,899 90,356,905 RGD:1600115
G Tmem14c transmembrane protein 14C JBrowse link 17 21,571,510 21,577,651 RGD:1600115
G Urod uroporphyrinogen decarboxylase JBrowse link 5 135,855,429 135,859,515 RGD:70052
RGD:13792537
RGD:1624291
RGD:2301379
G Uros uroporphyrinogen III synthase JBrowse link 1 205,755,766 205,778,170 RGD:1624291
RGD:13792537
heme O biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 JBrowse link 10 50,439,778 50,563,920 RGD:1600115
hypoxanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G Prps1 phosphoribosyl pyrophosphate synthetase 1 JBrowse link X 111,798,233 111,820,270 RGD:1624291
hypoxanthine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:13792537
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
RGD:1600115
G LOC103689983 hypoxanthine-guanine phosphoribosyltransferase JBrowse link X 158,623,231 158,655,277 RGD:1600115
melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:1624291
RGD:1600115
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1600115
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:1624291
RGD:1600115
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:1624291
RGD:13792537
melanin biosynthetic process from tyrosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
negative regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mfsd12 major facilitator superfamily domain containing 12 JBrowse link 7 11,214,832 11,223,713 RGD:1624291
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Slc24a5 solute carrier family 24 member 5 JBrowse link 3 117,335,212 117,354,480 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
RGD:13792537
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:1600115
RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
protoporphyrinogen IX biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:1600115
G Alas1 5'-aminolevulinate synthase 1 JBrowse link 8 114,927,704 114,941,038 RGD:1600115
G Alas2 5'-aminolevulinate synthase 2 JBrowse link X 23,167,576 23,187,356 RGD:1600115
G Cpox coproporphyrinogen oxidase JBrowse link 11 44,039,665 44,049,648 RGD:4145128
RGD:13792537
RGD:1600115
G Hmbs hydroxymethylbilane synthase JBrowse link 8 48,667,278 48,674,673 RGD:1600115
G Ireb2 iron responsive element binding protein 2 JBrowse link 8 59,450,974 59,503,634 RGD:1624291
RGD:1600115
G Ppox protoporphyrinogen oxidase JBrowse link 13 89,650,094 89,654,998 RGD:1600115
G Urod uroporphyrinogen decarboxylase JBrowse link 5 135,855,429 135,859,515 RGD:1600115
purine nucleobase biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:1600115
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:1624291
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:13792537
regulation of heme biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Srrd SRR1 domain containing JBrowse link 12 50,315,876 50,321,488 RGD:1624291
RGD:1600115
G Tmem14c transmembrane protein 14C JBrowse link 17 21,571,510 21,577,651 RGD:1624291
regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:1624291
xanthine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
zeaxanthin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:1624291
RGD:1600115
RGD:13792537

Term paths to the root
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Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      pigment metabolic process 67
        pigment biosynthetic process 51
          anthocyanin-containing compound biosynthetic process + 0
          aurone biosynthetic process 0
          carotenoid biosynthetic process + 1
          chlorophyll biosynthetic process + 0
          eye pigment biosynthetic process + 0
          flavone biosynthetic process + 0
          heme biosynthetic process + 20
          melanin biosynthetic process + 19
          ocellus pigment biosynthetic process + 0
          phlobaphene biosynthetic process 0
          phytochrome chromophore biosynthetic process 0
          pigment biosynthetic process involved in pigment accumulation + 0
          pteridine biosynthetic process 0
          purine nucleobase biosynthetic process + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.