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ONTOLOGY REPORT - ANNOTATIONS


Term:alcohol biosynthetic process
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Accession:GO:0046165 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
Synonyms:exact_synonym: alcohol anabolism;   alcohol biosynthesis;   alcohol formation;   alcohol synthesis


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aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CACNA1H calcium voltage-gated channel subunit alpha1 H JBrowse link 3 40,637,420 40,694,616 RGD:14298760
G LOC110260194 cytochrome P450 11B1, mitochondrial JBrowse link 4 1,365,725 1,373,138 RGD:14298760
calcitriol biosynthetic process from calciol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 JBrowse link 15 120,809,886 120,852,196 RGD:14298760
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase JBrowse link 5 23,053,129 23,058,865 RGD:14298760
G CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 JBrowse link 2 44,375,432 44,394,122 RGD:14298760
cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOA1 apolipoprotein A1 JBrowse link 9 44,216,481 44,218,360 RGD:14298760
G APOA4 apolipoprotein A4 JBrowse link 9 44,201,587 44,204,072 RGD:14298760
G CFTR CF transmembrane conductance regulator JBrowse link 18 28,627,717 28,818,209 RGD:14298760
G DHCR7 7-dehydrocholesterol reductase JBrowse link 2 2,377,352 2,391,846 RGD:14298760
G EBP EBP cholestenol delta-isomerase JBrowse link X 42,670,592 42,678,571 RGD:14298760
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 JBrowse link 14 14,976,259 15,010,701 RGD:14298760
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 84,380,245 84,401,117 RGD:14298760
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 4 101,420,941 101,440,302 RGD:14298760
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 JBrowse link 4 87,720,747 87,743,037 RGD:14298760
G INSIG1 insulin induced gene 1 JBrowse link 18 2,885,494 2,898,758 RGD:14298760
G INSIG2 insulin induced gene 2 JBrowse link 15 23,676,684 23,699,591 RGD:14298760
G LBR lamin B receptor JBrowse link 10 13,389,896 13,416,831 RGD:14298760
G LOC110255234 liver carboxylesterase-like RGD:14298760
G LSS lanosterol synthase RGD:14298760
G MVD mevalonate diphosphate decarboxylase JBrowse link 6 1,008,100 1,014,303 RGD:14298760
G MVK mevalonate kinase JBrowse link 14 41,320,790 41,357,437 RGD:14298760
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 JBrowse link 18 50,726,854 50,757,676 RGD:14298760
G PMVK phosphomevalonate kinase JBrowse link 4 94,861,500 94,913,743 RGD:14298760
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 16 25,745,902 25,783,524 RGD:14298760
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 6 155,683,392 155,754,283 RGD:14298760
G TM7SF2 transmembrane 7 superfamily member 2 JBrowse link 2 7,076,778 7,081,502 RGD:14298760
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP51 cytochrome P450, family 51, subfamily A, polypeptide 1 JBrowse link 9 72,057,506 72,079,587 RGD:14298760
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SC5D sterol-C5-desaturase JBrowse link 9 48,357,115 48,372,391 RGD:14298760
cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CACNA1H calcium voltage-gated channel subunit alpha1 H JBrowse link 3 40,637,420 40,694,616 RGD:14298760
dolichol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100525350 polyprenol reductase JBrowse link 8 42,024,352 42,049,209 RGD:14298760
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit JBrowse link 1 44,156,771 44,186,224 RGD:14298760
ergosterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 JBrowse link 14 104,561,394 104,567,099 RGD:14298760
G LOC100521659 cytochrome P450 26B1 JBrowse link 3 70,573,551 70,593,416 RGD:14298760
G LOC100739552 cytochrome P450 26C1 JBrowse link 14 104,550,901 104,558,977 RGD:14298760
glycerol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GOT1 glutamic-oxaloacetic transaminase 1 JBrowse link 14 110,608,422 110,635,825 RGD:14298760
G PGP phosphoglycolate phosphatase JBrowse link 3 39,776,815 39,779,669 RGD:14298760
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial JBrowse link 7 75,187,195 75,197,613 RGD:14298760
inositol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IMPA1 inositol monophosphatase 1 JBrowse link 4 54,935,838 54,968,672 RGD:14298760
G IMPA2 inositol monophosphatase 2 JBrowse link 6 97,280,008 97,309,729 RGD:14298760
G ISYNA1 inositol-3-phosphate synthase 1 JBrowse link 2 59,363,672 59,367,003 RGD:14298760
inositol phosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IP6K1 inositol hexakisphosphate kinase 1 JBrowse link 13 32,253,515 32,320,005 RGD:14298760
G IP6K2 inositol hexakisphosphate kinase 2 JBrowse link 13 31,379,516 31,406,989 RGD:14298760
G IP6K3 inositol hexakisphosphate kinase 3 JBrowse link 7 29,938,779 29,961,520 RGD:14298760
G IPMK inositol polyphosphate multikinase JBrowse link 14 92,383,471 92,428,732 RGD:14298760
G IPPK inositol-pentakisphosphate 2-kinase JBrowse link 3 42,308,001 42,368,162 RGD:14298760
G ITPKC inositol-trisphosphate 3-kinase C JBrowse link 6 48,943,207 48,962,101 RGD:14298760
G PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 JBrowse link 1 127,865,487 127,915,501 RGD:14298760
G PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 JBrowse link 2 108,596,733 108,690,859 RGD:14298760
inositol trisphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLCB1 phospholipase C beta 1 JBrowse link 17 17,007,197 17,745,314 RGD:14298760
G PLCB2 phospholipase C beta 2 JBrowse link 1 131,005,408 131,031,864 RGD:14298760
G PLCB3 phospholipase C beta 3 JBrowse link 2 7,844,931 7,860,183 RGD:14298760
G PLCB4 phospholipase C beta 4 JBrowse link 17 17,915,984 18,402,540 RGD:14298760
G PLCD1 phospholipase C delta 1 JBrowse link 13 22,851,581 22,872,950 RGD:14298760
G PLCD3 phospholipase C delta 3 JBrowse link 12 18,281,507 18,305,516 RGD:14298760
G PLCD4 phospholipase C delta 4 JBrowse link 15 120,660,549 120,695,731 RGD:14298760
G PLCE1 phospholipase C epsilon 1 JBrowse link 14 105,422,628 105,764,736 RGD:14298760
G PLCG1 phospholipase C gamma 1 JBrowse link 17 43,810,003 43,844,553 RGD:14298760
G PLCG2 phospholipase C gamma 2 JBrowse link 6 6,433,146 6,603,092 RGD:14298760
G PLCH1 phospholipase C eta 1 JBrowse link 13 95,402,015 95,644,647 RGD:14298760
G PLCH2 phospholipase C eta 2 JBrowse link 6 64,325,918 64,392,070 RGD:14298760
G PLCL1 phospholipase C like 1 JBrowse link 15 101,602,336 102,424,225 RGD:14298760
G PLCL2 phospholipase C like 2 JBrowse link 13 3,992,230 4,201,574 RGD:14298760
G PLCZ1 phospholipase C zeta 1 JBrowse link 5 54,257,709 54,452,557 RGD:14298760
G PTAFR platelet activating factor receptor JBrowse link 6 85,235,390 85,272,360 RGD:14298760
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP2 bone morphogenetic protein 2 JBrowse link 17 15,750,487 15,762,982 RGD:14298760
G BMP5 bone morphogenetic protein 5 JBrowse link 7 25,344,924 25,468,430 RGD:14298760
G LOC100621006 RE1-silencing transcription factor-like JBrowse link 8 56,048,280 56,215,011 RGD:14298760
G REST RE1 silencing transcription factor JBrowse link 8 56,035,182 56,061,140 RGD:14298760
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase JBrowse link 5 23,053,129 23,058,865 RGD:14298760
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 4 124,619,887 124,629,638 RGD:14298760
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 8 118,391,010 118,478,927 RGD:14298760
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:14298760
G ERLIN2 ER lipid raft associated 2 JBrowse link 15 48,643,722 48,662,648 RGD:14298760
G SOD1 superoxide dismutase 1 JBrowse link 13 195,326,573 195,335,273 RGD:14298760
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP2 bone morphogenetic protein 2 JBrowse link 17 15,750,487 15,762,982 RGD:14298760
G BMP5 bone morphogenetic protein 5 JBrowse link 7 25,344,924 25,468,430 RGD:14298760
G LOC100621006 RE1-silencing transcription factor-like JBrowse link 8 56,048,280 56,215,011 RGD:14298760
G REST RE1 silencing transcription factor JBrowse link 8 56,035,182 56,061,140 RGD:14298760
octopamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DBH dopamine beta-hydroxylase JBrowse link 1 273,204,407 273,225,562 RGD:14298760
G LOC100511166 DBH-like monooxygenase protein 2 JBrowse link 18 7,742,254 7,751,098 RGD:14298760
G MOXD1 monooxygenase DBH like 1 JBrowse link 1 31,282,491 31,367,589 RGD:14298760
phytosphingosine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACER3 alkaline ceramidase 3 JBrowse link 9 10,985,078 11,167,386 RGD:14298760
polyprenol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DHDDS dehydrodolichyl diphosphate synthase subunit JBrowse link 6 83,823,262 83,855,101 RGD:14298760
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP6 bone morphogenetic protein 6 JBrowse link 7 5,058,817 5,208,868 RGD:14298760
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:14298760
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:14298760
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCG1 ATP binding cassette subfamily G member 1 JBrowse link 13 205,561,897 205,628,428 RGD:14298760
G FGF1 fibroblast growth factor 1 JBrowse link 2 144,133,846 144,241,345 RGD:14298760
G SREBF1 sterol regulatory element binding transcription factor 1 JBrowse link 12 60,733,967 60,750,951 RGD:14298760
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AVPR1B arginine vasopressin receptor 1B JBrowse link 9 66,769,472 66,776,916 RGD:14298760
G CD244 CD244 molecule JBrowse link 4 89,668,221 89,700,974 RGD:14298760
G PTH parathyroid hormone JBrowse link 2 45,757,398 45,760,433 RGD:14298760
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:14298760
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 3 711,427 715,982 RGD:14298760
G LHCGR luteinizing hormone/choriogonadotropin receptor JBrowse link 3 91,964,415 92,023,821 RGD:14298760
protein deglycation, glyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:14298760
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VDR vitamin D receptor JBrowse link 5 78,205,807 78,266,505 RGD:14298760
regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOB apolipoprotein B JBrowse link 3 117,250,096 117,316,200 RGD:14298760
G SCAP SREBF chaperone JBrowse link 13 30,253,262 30,320,625 RGD:14298760
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PTK2B protein tyrosine kinase 2 beta JBrowse link 14 11,063,662 11,194,196 RGD:14298760
sphinganine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 JBrowse link 14 3,081,964 3,138,113 RGD:14298760
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 JBrowse link 7 100,545,360 100,638,973 RGD:14298760
sphingosine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACER1 alkaline ceramidase 1 JBrowse link 2 72,704,603 72,767,474 RGD:14298760
G ACER2 alkaline ceramidase 2 JBrowse link 1 203,387,669 203,415,018 RGD:14298760
G ACER3 alkaline ceramidase 3 JBrowse link 9 10,985,078 11,167,386 RGD:14298760
G ASAH1 N-acylsphingosine amidohydrolase 1 JBrowse link 17 5,712,048 5,749,811 RGD:14298760
G ASAH2 N-acylsphingosine amidohydrolase 2 JBrowse link 14 99,018,111 99,141,374 RGD:14298760
G GBA glucosylceramidase beta JBrowse link 4 94,583,905 94,606,689 RGD:14298760
G SPHK1 sphingosine kinase 1 JBrowse link 12 5,114,946 5,122,580 RGD:14298760
G SPHK2 sphingosine kinase 2 JBrowse link 6 53,982,911 53,986,779 RGD:14298760
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 JBrowse link 14 3,081,964 3,138,113 RGD:14298760
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 JBrowse link 7 100,545,360 100,638,973 RGD:14298760
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DHFR dihydrofolate reductase JBrowse link 2 89,230,660 89,255,830 RGD:14298760
G GCH1 GTP cyclohydrolase 1 JBrowse link 1 184,201,232 184,264,060 RGD:14298760
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 JBrowse link 14 73,769,339 73,807,278 RGD:14298760
G PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 JBrowse link 2 137,082,920 137,135,175 RGD:14298760
G PTS 6-pyruvoyltetrahydropterin synthase JBrowse link 9 39,920,157 39,927,804 RGD:14298760
G QDPR quinoid dihydropteridine reductase JBrowse link 8 12,529,500 12,549,471 RGD:14298760
G SPR sepiapterin reductase JBrowse link 3 69,889,448 69,894,747 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9064
      small molecule metabolic process 1272
        alcohol metabolic process 232
          alcohol biosynthetic process 110
            amino acid catabolic process to alcohol via Ehrlich pathway + 0
            cellular alcohol biosynthetic process + 6
            cyclopentanol biosynthetic process 0
            fatty alcohol biosynthetic process + 0
            fonsecin biosynthetic process 0
            monensin A biosynthetic process 0
            negative regulation of alcohol biosynthetic process + 10
            octopamine biosynthetic process 3
            polyol biosynthetic process + 57
            polyprenol biosynthetic process + 3
            positive regulation of alcohol biosynthetic process + 12
            prenol biosynthetic process 0
            primary alcohol biosynthetic process + 8
            regulation of alcohol biosynthetic process + 26
            secondary alcohol biosynthetic process + 34
            tertiary alcohol biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9064
      organic substance metabolic process 8517
        organic substance biosynthetic process 4366
          organic hydroxy compound biosynthetic process 171
            alcohol biosynthetic process 110
              amino acid catabolic process to alcohol via Ehrlich pathway + 0
              cellular alcohol biosynthetic process + 6
              cyclopentanol biosynthetic process 0
              fatty alcohol biosynthetic process + 0
              fonsecin biosynthetic process 0
              monensin A biosynthetic process 0
              negative regulation of alcohol biosynthetic process + 10
              octopamine biosynthetic process 3
              polyol biosynthetic process + 57
              polyprenol biosynthetic process + 3
              positive regulation of alcohol biosynthetic process + 12
              prenol biosynthetic process 0
              primary alcohol biosynthetic process + 8
              regulation of alcohol biosynthetic process + 26
              secondary alcohol biosynthetic process + 34
              tertiary alcohol biosynthetic process + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.