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ONTOLOGY REPORT - ANNOTATIONS


Term:aflatoxin metabolic process
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Accession:GO:0046222 term browser browse the term
Definition:The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms:exact_synonym: aflatoxin metabolism
 narrow_synonym: aflatoxin B metabolic process
 related_synonym: aflatoxin B1 metabolic process;   aflatoxin B1 metabolism;   aflatoxin B2 metabolic process;   aflatoxin B2 metabolism
 alt_id: GO:0043389;   GO:0043390;   GO:0043391


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aflatoxin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:632009
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 JBrowse link 12 17,382,749 17,387,909 RGD:1624291
aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:1304380
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:12910550

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  biological_process 19676
    metabolic process 11952
      secondary metabolic process 64
        toxin metabolic process 19
          mycotoxin metabolic process 4
            aflatoxin metabolic process 4
              aflatoxin biosynthetic process + 0
              aflatoxin catabolic process 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.