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ONTOLOGY REPORT - ANNOTATIONS


Term:aflatoxin catabolic process
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Accession:GO:0046223 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms:exact_synonym: aflatoxin breakdown;   aflatoxin catabolism;   aflatoxin degradation


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aflatoxin catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO RGD PMID:27071940 RGD:12910550 NCBI chrNW_004955403:19,510,122...19,536,428 JBrowse link

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Path 1
Term Annotations click to browse term
  biological_process 11857
    detoxification 39
      toxin catabolic process 1
        mycotoxin catabolic process 1
          aflatoxin catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 11857
    response to stimulus 6353
      response to chemical 3715
        response to toxic substance 187
          detoxification 39
            toxin catabolic process 1
              mycotoxin catabolic process 1
                aflatoxin catabolic process 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.