Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:aflatoxin catabolic process
go back to main search page
Accession:GO:0046223 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms:exact_synonym: aflatoxin breakdown;   aflatoxin catabolism;   aflatoxin degradation


show annotations for term's descendants           Sort by:
 
aflatoxin catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta3 glutathione S-transferase, alpha 3 IMP (MGI:MGI:4429761|PMID:19850059) MGI PMID:19850059 MGI:MGI:4429761 NCBI chr 1:21,240,565...21,265,575
Ensembl chr 1:21,240,589...21,265,661
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23366
    detoxification 68
      toxin catabolic process 2
        mycotoxin catabolic process 2
          aflatoxin catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 23366
    response to stimulus 10281
      response to chemical 5344
        response to toxic substance 240
          detoxification 68
            toxin catabolic process 2
              mycotoxin catabolic process 2
                aflatoxin catabolic process 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.