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ONTOLOGY REPORT - ANNOTATIONS


Term:glycerophospholipid catabolic process
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Accession:GO:0046475 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
Synonyms:exact_synonym: glycerophospholipid breakdown;   glycerophospholipid catabolism;   glycerophospholipid degradation;   phosphoglyceride catabolic process;   phosphoglyceride catabolism


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glycerophospholipid catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase ISO (PMID:25290914) RGD PMID:25290914 NCBI chr 3:146,630,298...146,690,375
Ensembl chr 3:146,630,299...146,690,375
JBrowse link
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:74,334,972...74,376,332
Ensembl chr10:74,334,975...74,376,270
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607
JBrowse link
G Lipc lipase C, hepatic type IDA phosphatidylcholine, phosphatidylethanolamine hydrolysis RGD PMID:9048565 RGD:2308766 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Pla2g4a phospholipase A2 group IVA IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g4b phospholipase A2 group IVB ISO
IBA
(PMID:10085124)
PMID:21873635
RGD PMID:10085124, PMID:21873635 RGD:13792537 NCBI chr 3:111,824,919...111,833,526
Ensembl chr 3:111,825,162...111,834,210
JBrowse link
G Pla2g4c phospholipase A2 group IVC ISO
IBA
(PMID:10085124)
PMID:21873635
RGD PMID:10085124, PMID:21873635 RGD:13792537 NCBI chr 1:75,440,035...75,481,995
Ensembl chr 1:75,428,027...75,620,911
JBrowse link
G Pla2g4d phospholipase A2 group IVD ISO
IBA
(PMID:14709560)
PMID:21873635
RGD PMID:14709560, PMID:21873635 RGD:13792537 NCBI chr 3:112,040,827...112,061,847
Ensembl chr 3:112,041,533...112,061,796
JBrowse link
G Pla2g4e phospholipase A2, group IVE IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,952,396...112,018,470
Ensembl chr 3:111,952,348...111,994,337
JBrowse link
G Pla2g4f phospholipase A2, group IVF IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:112,068,617...112,083,978
Ensembl chr 3:112,072,330...112,084,144
JBrowse link
G Prdx6 peroxiredoxin 6 ISO (PMID:10893423) RGD PMID:10893423 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 ISO
IBA
(PMID:16517606)
PMID:21873635
RGD PMID:16517606, PMID:21873635 RGD:13792537 NCBI chr11:87,522,971...87,546,687
Ensembl chr11:87,522,971...87,546,687
JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 ISO (PMID:2302419) RGD PMID:2302419 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
phosphatidylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IDA
IEA
IBA
ISO
PMID:21240271
GO_REF:0000107
PMID:21873635
(MGI:MGI:5050048|PMID:21240269)
(PMID:21240271)
Ensembl
RGD
PMID:21240269, PMID:21240271, PMID:21240271, PMID:21873635 GO_REF:0000107, MGI:MGI:5050048, RGD:8553522, RGD:13792537 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 ISO (MGI:MGI:5616003|PMID:25528375) RGD PMID:25528375 MGI:MGI:5616003 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Pla2g10 phospholipase A2, group X ISO
IEA
(PMID:12021277)
GO_REF:0000107
RGD
Ensembl
PMID:12021277 GO_REF:0000107 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g15 phospholipase A2, group XV ISS
ISO
GO_REF:0000024
(MGI:MGI:3654404|PMID:16880524), (MGI:MGI:3694368|PMID:16837646), (MGI:MGI:6392937|PMID:17626977)
UniProt
RGD
PMID:16837646, PMID:16880524, PMID:17626977 GO_REF:0000024, MGI:MGI:3654404, MGI:MGI:3694368, MGI:MGI:6392937 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA
ISO
ISS
GO_REF:0000107
(PMID:12672805), (PMID:14709560), (PMID:17472963), (PMID:7794891), (PMID:9425121)
GO_REF:0000024
(MGI:MGI:1100763|PMID:9403693)
Ensembl
RGD
UniProt
PMID:7794891, PMID:9403693, PMID:9425121, PMID:12672805, PMID:14709560, PMID:17472963 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1100763 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g5 phospholipase A2, group V ISO
ISS
(PMID:23533611)
GO_REF:0000024
RGD
UniProt
PMID:23533611 GO_REF:0000024 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Pla2g6 phospholipase A2 group VI ISS
ISO
GO_REF:0000024
(PMID:20886109)
UniProt
RGD
PMID:20886109 GO_REF:0000024 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO (PMID:2040620) RGD PMID:2040620 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plb1 phospholipase B1 IDA PMID:9442065
PMID:9442064
UniProt PMID:9442065, PMID:9442064 RGD:633237, RGD:30309923 NCBI chr 6:25,375,699...25,507,108
Ensembl chr 6:25,397,537...25,507,073
JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 ISO
IEA
ISS
(PMID:17401110)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17401110 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:279,896,973...279,927,600
Ensembl chr 1:279,896,973...279,927,600
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6393153|PMID:28887301)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28887301 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6393153 NCBI chr 3:2,182,191...2,261,890
Ensembl chr 3:2,182,957...2,261,878
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 ISO (PMID:15695510) RGD PMID:15695510 NCBI chr 6:64,224,870...64,288,465
Ensembl chr 6:64,224,861...64,286,785
JBrowse link
phosphatidylethanolamine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g15 phospholipase A2, group XV ISS
ISO
GO_REF:0000024
(MGI:MGI:3654404|PMID:16880524), (MGI:MGI:3694368|PMID:16837646)
UniProt
RGD
PMID:16837646, PMID:16880524 GO_REF:0000024, MGI:MGI:3654404, MGI:MGI:3694368 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956
JBrowse link
G Pla2g6 phospholipase A2 group VI ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Plb1 phospholipase B1 IDA PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr 6:25,375,699...25,507,108
Ensembl chr 6:25,397,537...25,507,073
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 ISO (PMID:15695510) RGD PMID:15695510 NCBI chr 6:64,224,870...64,288,465
Ensembl chr 6:64,224,861...64,286,785
JBrowse link
phosphatidylglycerol catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g4a phospholipase A2 group IVA ISO
ISS
IEA
(PMID:9425121)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:9425121 GO_REF:0000024, GO_REF:0000107 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plb1 phospholipase B1 IDA PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr 6:25,375,699...25,507,108
Ensembl chr 6:25,397,537...25,507,073
JBrowse link
phosphatidylinositol catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inpp5f inositol polyphosphate-5-phosphatase F ISO MGI:MGI:4128518 (MGI:MGI:4943859|PMID:19875726) RGD PMID:19875726 MGI:MGI:4943859 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524
JBrowse link
G Plcb1 phospholipase C beta 1 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plcb3 phospholipase C beta 3 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
JBrowse link
phosphatidylserine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase ISO
IBA
ISS
MGI:MGI:5487621 (MGI:MGI:5469248|PMID:23297193)
PMID:21873635
(PMID:30643283)
GO_REF:0000024
RGD
UniProt
PMID:23297193, PMID:30643283, PMID:21873635 GO_REF:0000024, MGI:MGI:5469248, RGD:13792537 NCBI chr 3:146,630,298...146,690,375
Ensembl chr 3:146,630,299...146,690,375
JBrowse link
G Abhd12b abhydrolase domain containing 12B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:92,568,975...92,596,327
Ensembl chr 6:92,568,975...92,596,327
JBrowse link
G Abhd16a abhydrolase domain containing 16A, phospholipase ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:MGI:5779796|PMID:25580854)
UniProt
RGD
PMID:25580854, PMID:21873635 GO_REF:0000024, MGI:MGI:5779796, RGD:13792537 NCBI chr20:5,080,070...5,094,935
Ensembl chr20:5,080,070...5,094,935
JBrowse link
G Abhd16b abhydrolase domain containing 16B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:176,985,900...176,987,797
Ensembl chr 3:176,985,900...176,987,796
JBrowse link
platelet activating factor catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g10 phospholipase A2, group X ISO
IEA
ISS
(PMID:16962371)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16962371 GO_REF:0000024, GO_REF:0000107 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO (PMID:16371369) RGD PMID:16371369 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO
IEA
(MGI:MGI:3784112|PMID:18175806)
GO_REF:0000107
RGD
Ensembl
PMID:18175806 GO_REF:0000107, MGI:MGI:3784112 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO (MGI:MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:MGI:3784112 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      catabolic process 2560
        cellular catabolic process 2185
          cellular lipid catabolic process 233
            phospholipid catabolic process 53
              glycerophospholipid catabolic process 32
                CDP-diacylglycerol catabolic process 0
                phosphatidylcholine catabolic process + 15
                phosphatidylethanolamine catabolic process 4
                phosphatidylglycerol catabolic process 2
                phosphatidylinositol catabolic process + 3
                phosphatidylserine catabolic process 4
                platelet activating factor catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular metabolic process 11085
        phosphorus metabolic process 3301
          phosphate-containing compound metabolic process 3280
            phospholipid metabolic process 381
              glycerophospholipid metabolic process 293
                glycerophospholipid catabolic process 32
                  CDP-diacylglycerol catabolic process 0
                  phosphatidylcholine catabolic process + 15
                  phosphatidylethanolamine catabolic process 4
                  phosphatidylglycerol catabolic process 2
                  phosphatidylinositol catabolic process + 3
                  phosphatidylserine catabolic process 4
                  platelet activating factor catabolic process 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.