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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of centrosome cycle
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Accession:GO:0046605 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.


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regulation of centrosome cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf5 activating transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:26213385)
Ensembl
UniProt
RGD
PMID:26213385 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IDA RGD PMID:10545494 RGD:70723 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IMP RGD PMID:24388750 RGD:10047173 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mark4 microtubule affinity regulating kinase 4 ISO (PMID:25123532) RGD PMID:25123532 NCBI chr 1:80,335,517...80,367,366
Ensembl chr 1:80,335,526...80,367,328
JBrowse link
G Mcph1 microcephalin 1 ISO MGI:5308745 (MGI:5306866|PMID:21947081) RGD PMID:21947081 MGI:5306866 NCBI chr16:75,904,087...76,110,624
Ensembl chr16:75,904,006...76,110,553
JBrowse link
G Wdr62 WD repeat domain 62 IMP RGD PMID:24388750 RGD:10047173 NCBI chr 1:90,995,545...91,034,592
Ensembl chr 1:88,694,824...88,734,223
JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:4830038|PMID:20627074)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20627074 GO_REF:0000024, GO_REF:0000107, MGI:4830038 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Kat2a lysine acetyltransferase 2A ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kat2b lysine acetyltransferase 2B ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Mdm1 Mdm1 nuclear protein IEA
ISS
ISO
GO_REF:0000002
GO_REF:0000024
(PMID:26337392)
InterPro
UniProt
RGD
PMID:26337392 GO_REF:0000002, GO_REF:0000024 NCBI chr 7:61,165,652...61,200,865
Ensembl chr 7:61,165,640...61,200,879
JBrowse link
G Rbm14 RNA binding motif protein 14 ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:220,048,740...220,067,124
Ensembl chr 1:220,048,873...220,067,124
JBrowse link
G Trim37 tripartite motif-containing 37 ISO
IBA
(PMID:23769972)
PMID:21873635
RGD PMID:23769972, PMID:21873635 RGD:13792537 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F ISO
ISS
(PMID:20596027)
(MGI:4819440|PMID:20596027)
GO_REF:0000024
RGD
UniProt
PMID:20596027 GO_REF:0000024, MGI:4819440 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Cenatac centrosomal AT-AC splicing factor ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 8:48,729,695...48,736,574
Ensembl chr 8:48,729,835...48,736,506
JBrowse link
G Npm1 nucleophosmin 1 ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nubp1 nucleotide binding protein 1 ISO (MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652) RGD PMID:16638812, PMID:23028652 MGI:3625381, MGI:5463135 NCBI chr10:5,333,378...5,343,949
Ensembl chr10:5,333,378...5,344,121
JBrowse link
G Tmem67 transmembrane protein 67 IMP
ISO
IEA
(MGI:4353840|PMID:19515853)
(PMID:19515853)
GO_REF:0000107
RGD
Ensembl
PMID:19515853, PMID:19515853 GO_REF:0000107, MGI:4353840, RGD:8554306 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep120 centrosomal protein 120 ISO
IBA
(PMID:27185865)
PMID:21873635
RGD PMID:27185865, PMID:21873635 RGD:13792537 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep295 centrosomal protein 295 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:27185865)
UniProt
Ensembl
RGD
PMID:27185865 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup62 nucleoporin 62 ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:100,811,140...100,827,119
Ensembl chr 1:100,811,755...100,827,111
JBrowse link
G Plk4 polo-like kinase 4 ISS
ISO
GO_REF:0000024
(PMID:16244668), (PMID:17681131), (PMID:22349705), (PMID:27796307)
UniProt
RGD
PMID:16244668, PMID:17681131, PMID:22349705, PMID:27796307 GO_REF:0000024 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
positive regulation of centrosome duplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IMP RGD PMID:17667942 RGD:14700805 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Cep120 centrosomal protein 120 ISO (MGI:5635753|PMID:25251415) RGD PMID:25251415 MGI:5635753 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep295 centrosomal protein 295 ISS
ISO
GO_REF:0000024
(PMID:25131205)
UniProt
RGD
PMID:25131205 GO_REF:0000024 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Npm1 nucleophosmin 1 ISO UniProtKB:Q28201 (MGI:3697024|PMID:17015463) RGD PMID:17015463 MGI:3697024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Poc1a POC1 centriolar protein A ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:114,982,764...115,050,844
Ensembl chr 8:114,986,326...115,050,728
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 IEA
ISO
GO_REF:0000002
(MGI:3697024|PMID:17015463)
InterPro
RGD
PMID:17015463 GO_REF:0000002, MGI:3697024 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
regulation of centriole replication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Cenpj centromere protein J ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep295 centrosomal protein 295 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Cep295nl CEP295 N-terminal like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:107,363,511...107,381,280
Ensembl chr10:107,363,511...107,376,645
JBrowse link
G Cep76 centrosomal protein 76 ISO (PMID:19460342) RGD PMID:19460342 NCBI chr18:63,364,990...63,394,766
Ensembl chr18:63,359,832...63,394,766
JBrowse link
G LOC100302465 hypothetical LOC100302465 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:206,324,763...206,417,143
Ensembl chr 1:206,324,765...206,417,143
JBrowse link
G Npm1 nucleophosmin 1 ISO
ISS
(PMID:20352051)
GO_REF:0000024
RGD
UniProt
PMID:20352051 GO_REF:0000024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Plk2 polo-like kinase 2 ISS
ISO
GO_REF:0000024
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)
UniProt
RGD
PMID:15242618, PMID:19001868, PMID:20352051, PMID:20531387 GO_REF:0000024 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Spice1 spindle and centriole associated protein 1 ISO
IBA
ISS
(PMID:20736305)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20736305, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:61,250,649...61,294,116
Ensembl chr11:61,251,696...61,294,022
JBrowse link
G Stil STIL, centriolar assembly protein ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416
JBrowse link
regulation of centrosome duplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007744.2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:26,869,828...26,870,421 JBrowse link
G AABR07025089.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:28,072,014...28,166,296 JBrowse link
G AABR07041089.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:118,996,333...118,998,300 JBrowse link
G AABR07055527.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:4,951,747...4,952,584 JBrowse link
G AABR07067023.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:26,636,334...26,707,571 JBrowse link
G AABR07067024.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:26,727,162...26,734,763 JBrowse link
G Cep131 centrosomal protein 131 ISO
IBA
(PMID:22797915)
PMID:21873635
RGD PMID:22797915, PMID:21873635 RGD:13792537 NCBI chr10:109,243,240...109,267,636
Ensembl chr10:109,243,039...109,267,500
JBrowse link
G Chmp1a charged multivesicular body protein 1A ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Chmp1b charged multivesicular body protein 1B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:62,923,620...62,926,150 JBrowse link
G Chmp2a charged multivesicular body protein 2A ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
G Chmp2b charged multivesicular body protein 2B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:2,666,405...2,692,213
Ensembl chr11:2,665,285...2,692,198
JBrowse link
G Chmp3 charged multivesicular body protein 3 ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
G Chmp4b charged multivesicular body protein 4B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chmp4c charged multivesicular body protein 4C IEA
ISO
GO_REF:0000107
(PMID:20616062)
Ensembl
RGD
PMID:20616062 GO_REF:0000107 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Chmp5 charged multivesicular body protein 5 ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 ISS
ISO
GO_REF:0000024
(MGI:4441223|PMID:20230755)
UniProt
RGD
PMID:20230755 GO_REF:0000024, MGI:4441223 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 ISO
ISS
(PMID:21725316)
GO_REF:0000024
RGD
UniProt
PMID:21725316 GO_REF:0000024 NCBI chr 3:2,726,705...2,731,213
Ensembl chr 3:2,727,254...2,731,212
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease ISO (PMID:23108668), (PMID:23166748) RGD PMID:23108668, PMID:23166748 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Nat10 N-acetyltransferase 10 ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 3:93,658,119...93,698,136
Ensembl chr 3:93,658,117...93,698,136
JBrowse link
G Npm1 nucleophosmin 1 IBA
ISO
PMID:21873635
MGI:3604807 (MGI:3604166|PMID:16007073)
RGD PMID:16007073, PMID:21873635 MGI:3604166, RGD:13792537 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin ISO (PMID:20554582) RGD PMID:20554582 NCBI chr 9:26,164,969...26,736,704 JBrowse link
G Sirt1 sirtuin 1 ISO
ISS
(PMID:31722219)
GO_REF:0000024
RGD
UniProt
PMID:31722219 GO_REF:0000024 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
G Xpo1 exportin 1 ISO (MGI:3610707|PMID:16297385) RGD PMID:16297385 MGI:3610707 NCBI chr14:108,007,421...108,049,088
Ensembl chr14:108,007,724...108,049,660
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cell cycle process 1210
        centrosome cycle 138
          regulation of centrosome cycle 57
            negative regulation of centrosome cycle + 11
            positive regulation of centrosome cycle 0
            regulation of centrosome duplication + 51
Path 2
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            cytoskeleton organization 1459
              microtubule cytoskeleton organization 645
                microtubule organizing center organization 150
                  centrosome cycle 138
                    regulation of centrosome cycle 57
                      negative regulation of centrosome cycle + 11
                      positive regulation of centrosome cycle 0
                      regulation of centrosome duplication + 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.