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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of centrosome cycle
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Accession:GO:0046605 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.


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regulation of centrosome cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATF5 activating transcription factor 5 JBrowse link 19 49,928,702 49,933,936 RGD:2290271
G AURKA aurora kinase A JBrowse link 20 56,369,389 56,392,337 RGD:2290271
G MARK4 microtubule affinity regulating kinase 4 JBrowse link 19 45,251,271 45,305,284 RGD:2290271
G MCPH1 microcephalin 1 JBrowse link 8 6,406,592 6,648,508 RGD:2290271
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCP110 centriolar coiled-coil protein 110 JBrowse link 16 19,523,879 19,553,408 RGD:2290271
G CHMP2A charged multivesicular body protein 2A JBrowse link 19 58,551,566 58,555,624 RGD:2290271
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRCA1 BRCA1 DNA repair associated JBrowse link 17 43,044,295 43,125,364 RGD:2290271
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 JBrowse link 9 120,388,869 120,580,170 RGD:2290271
G KAT2A lysine acetyltransferase 2A JBrowse link 17 42,113,111 42,121,367 RGD:2290271
G KAT2B lysine acetyltransferase 2B JBrowse link 3 20,040,407 20,154,404 RGD:2290271
G MDM1 Mdm1 nuclear protein JBrowse link 12 68,294,566 68,332,414 RGD:2290271
G RBM14 RNA binding motif protein 14 JBrowse link 11 66,616,630 66,629,934 RGD:2290271
G RBM14-RBM4 RBM14-RBM4 readthrough JBrowse link 11 66,616,582 66,646,473 RGD:2290271
G TRIM37 tripartite motif containing 37 JBrowse link 17 58,968,010 59,106,880 RGD:2290271
negative regulation of centriole-centriole cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NEK2 NIMA related kinase 2 JBrowse link 1 211,658,256 211,675,630 RGD:2290271
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCNF cyclin F JBrowse link 16 2,429,447 2,458,854 RGD:2290271
G NPM1 nucleophosmin 1 JBrowse link 5 171,387,116 171,410,884 RGD:2290271
G NUBP1 nucleotide binding protein 1 JBrowse link 16 10,743,164 10,769,351 RGD:2290271
G TMEM67 transmembrane protein 67 JBrowse link 8 93,754,844 93,832,653 RGD:2290271
negative regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KIF25 kinesin family member 25 JBrowse link 6 167,999,092 168,045,107 RGD:2290271
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPJ centromere protein J JBrowse link 13 24,882,279 24,922,889 RGD:2290271
G CEP120 centrosomal protein 120 JBrowse link 5 123,344,885 123,423,842 RGD:2290271
G CEP295 centrosomal protein 295 JBrowse link 11 93,661,682 93,730,381 RGD:2290271
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 63,389,190 63,422,495 RGD:2290271
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NUP62 nucleoporin 62 JBrowse link 19 49,906,825 49,929,504 RGD:2290271
G PLK4 polo like kinase 4 JBrowse link 4 127,880,893 127,899,224 RGD:2290271
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP120 centrosomal protein 120 JBrowse link 5 123,344,885 123,423,842 RGD:2290271
G CEP295 centrosomal protein 295 JBrowse link 11 93,661,682 93,730,381 RGD:2290271
G POC1A POC1 centriolar protein A JBrowse link 3 52,075,226 52,154,423 RGD:2290271
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2 11,179,759 11,345,437 RGD:2290271
positive regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NSFL1C NSFL1 cofactor JBrowse link 20 1,442,162 1,467,793 RGD:2290271
G RANBP1 RAN binding protein 1 JBrowse link 22 20,116,104 20,127,355 RGD:2290271
G UBXN2B UBX domain protein 2B JBrowse link 8 58,411,264 58,451,501 RGD:2290271
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 2 73,385,758 73,609,919 RGD:2290271
G C10orf90 chromosome 10 open reading frame 90 JBrowse link 10 126,424,997 126,670,510 RGD:2290271
G CENPJ centromere protein J JBrowse link 13 24,882,279 24,922,889 RGD:2290271
G CEP295 centrosomal protein 295 JBrowse link 11 93,661,682 93,730,381 RGD:2290271
G CEP295NL CEP295 N-terminal like JBrowse link 17 78,890,579 78,903,201 RGD:2290271
G CEP76 centrosomal protein 76 JBrowse link 18 12,661,956 12,702,777 RGD:2290271
G NPM1 nucleophosmin 1 JBrowse link 5 171,387,116 171,410,884 RGD:2290271
G PLK2 polo like kinase 2 JBrowse link 5 58,453,982 58,460,139 RGD:2290271
G SPICE1 spindle and centriole associated protein 1 JBrowse link 3 113,442,718 113,515,156 RGD:2290271
G STIL STIL centriolar assembly protein JBrowse link 1 47,250,139 47,314,896 RGD:2290271
regulation of centriole-centriole cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP250 centrosomal protein 250 JBrowse link 20 35,455,137 35,519,280 RGD:2290271
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,445 RGD:2290271
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP131 centrosomal protein 131 JBrowse link 17 81,189,595 81,222,989 RGD:2290271
G CHMP1A charged multivesicular body protein 1A JBrowse link 16 89,644,435 89,657,708 RGD:2290271
G CHMP1B charged multivesicular body protein 1B JBrowse link 18 11,851,413 11,854,444 RGD:2290271
G CHMP2A charged multivesicular body protein 2A JBrowse link 19 58,551,566 58,555,624 RGD:2290271
G CHMP2B charged multivesicular body protein 2B JBrowse link 3 87,227,309 87,255,556 RGD:2290271
G CHMP3 charged multivesicular body protein 3 JBrowse link 2 86,503,430 86,563,443 RGD:2290271
G CHMP4B charged multivesicular body protein 4B JBrowse link 20 33,811,348 33,854,366 RGD:2290271
G CHMP4C charged multivesicular body protein 4C JBrowse link 8 81,732,448 81,759,515 RGD:2290271
G CHMP5 charged multivesicular body protein 5 JBrowse link 9 33,264,879 33,282,070 RGD:2290271
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 11 90,200,429 90,223,364 RGD:2290271
G FBXW5 F-box and WD repeat domain containing 5 JBrowse link 9 136,940,435 136,944,774 RGD:2290271
G GEN1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 2 17,753,687 17,788,946 RGD:2290271
G NPM1 nucleophosmin 1 JBrowse link 5 171,387,116 171,410,884 RGD:2290271
G PDCD6IP programmed cell death 6 interacting protein JBrowse link 3 33,798,571 33,869,707 RGD:2290271
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 6 51,614,685 52,087,625 RGD:2290271
G RAB6C RAB6C, member RAS oncogene family JBrowse link 2 129,979,666 129,982,738 RGD:2290271
G RNF103-CHMP3 RNF103-CHMP3 readthrough JBrowse link 2 86,503,430 86,721,122 RGD:2290271
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 63,389,190 63,422,495 RGD:2290271
G XPO1 exportin 1 JBrowse link 2 61,477,849 61,538,522 RGD:2290271
G XRCC3 X-ray repair cross complementing 3 JBrowse link 14 103,697,611 103,715,486 RGD:2290271
regulation of mitotic centrosome separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP85 centrosomal protein 85 JBrowse link 1 26,234,179 26,278,808 RGD:2290271
G CHEK1 checkpoint kinase 1 JBrowse link 11 125,624,910 125,676,256 RGD:2290271
G KIF11 kinesin family member 11 JBrowse link 10 92,593,130 92,655,395 RGD:2290271
G MAP9 microtubule associated protein 9 JBrowse link 4 155,342,658 155,376,970 RGD:2290271
G NEK2 NIMA related kinase 2 JBrowse link 1 211,658,256 211,675,630 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18104
    cellular process 17121
      cell cycle process 1415
        centrosome cycle 129
          regulation of centrosome cycle 61
            negative regulation of centrosome cycle + 16
            positive regulation of centrosome cycle + 11
            regulation of centriole-centriole cohesion + 3
            regulation of centrosome duplication + 46
            regulation of mitotic centrosome separation + 9
Path 2
Term Annotations click to browse term
  biological_process 18104
    cellular process 17121
      cellular component organization or biogenesis 6720
        cellular component organization 6532
          organelle organization 4095
            cytoskeleton organization 1427
              microtubule cytoskeleton organization 619
                microtubule organizing center organization 139
                  centrosome cycle 129
                    regulation of centrosome cycle 61
                      negative regulation of centrosome cycle + 16
                      positive regulation of centrosome cycle + 11
                      regulation of centriole-centriole cohesion + 3
                      regulation of centrosome duplication + 46
                      regulation of mitotic centrosome separation + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.