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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.


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regulation of bone remodeling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:1624291
G Inpp4b inositol polyphosphate-4-phosphatase type II B JBrowse link 19 29,592,889 30,341,528 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:1600115
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:1624291
RGD:1600115
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:1600115
RGD:1624291
G Mepe matrix extracellular phosphoglycoprotein JBrowse link 14 6,782,011 6,793,561 RGD:70633
G Suco SUN domain containing ossification factor JBrowse link 13 79,736,485 79,801,133 RGD:1600115
RGD:13792537
RGD:1624291
G Syt7 synaptotagmin 7 JBrowse link 1 226,435,816 226,498,008 RGD:1624291
RGD:1600115
negative regulation of bone remodeling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
negative regulation of bone resorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:1624291
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:2307268
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Cldn18 claudin 18 JBrowse link 8 107,933,725 107,960,656 RGD:1624291
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:5134371
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:7257714
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:1624291
G Gpr137b G protein-coupled receptor 137B JBrowse link 17 90,670,852 90,709,003 RGD:1624291
RGD:13792537
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Iapp islet amyloid polypeptide JBrowse link 4 176,509,863 176,517,903 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Tmem119 transmembrane protein 119 JBrowse link 12 48,598,498 48,605,704 RGD:1624291
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:730196
RGD:1624170
G Ubash3b ubiquitin associated and SH3 domain containing, B JBrowse link 8 45,224,053 45,375,450 RGD:1624291
RGD:13792537
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1580559
positive regulation of bone resorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam8 ADAM metallopeptidase domain 8 JBrowse link 1 212,317,510 212,332,895 RGD:1624291
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1625797
G Atp6ap1 ATPase H+ transporting accessory protein 1 JBrowse link X 156,407,973 156,415,053 RGD:1600115
RGD:1624291
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:1600722
G Dcstamp dendrocyte expressed seven transmembrane protein JBrowse link 7 78,642,016 78,651,763 RGD:1624291
G Def8 differentially expressed in FDCP 8 homolog JBrowse link 19 56,238,353 56,259,867 RGD:1624291
RGD:1600115
G Dlk1 delta like non-canonical Notch ligand 1 JBrowse link 6 133,576,513 133,583,751 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:10395245
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:1624291
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:1624291
G Idua alpha-L-iduronidase JBrowse link 14 2,041,828 2,056,762 RGD:1624291
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:5024929
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:1624291
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:1624291
G Oscar osteoclast associated Ig-like receptor JBrowse link 1 64,182,174 64,188,658 RGD:1624291
G Plekhm1 pleckstrin homology and RUN domain containing M1 JBrowse link 10 91,451,890 91,500,675 RGD:1624291
RGD:1600115
G Ppargc1b PPARG coactivator 1 beta JBrowse link 18 56,626,725 56,650,524 RGD:1624291
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1624291
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:729815
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581129
RGD:13792537
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tf transferrin JBrowse link 8 111,694,570 111,721,275 RGD:1624291
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Tmem64 transmembrane protein 64 JBrowse link 5 28,850,864 28,898,203 RGD:1624291
G Tnfrsf11a TNF receptor superfamily member 11A JBrowse link 13 25,778,306 25,835,802 RGD:1624291
RGD:13792537
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:730134
RGD:1624291
regulation of bone resorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:1342423
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:2293713
G Gpr137 G protein-coupled receptor 137 JBrowse link 1 222,194,266 222,197,252 RGD:13792537
G Il20ra interleukin 20 receptor subunit alpha JBrowse link 1 15,180,328 15,222,785 RGD:1624291
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:1624291
RGD:1600115
G Siglec15 sialic acid binding Ig-like lectin 15 JBrowse link 18 74,403,384 74,417,333 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    multicellular organismal process 8910
      tissue remodeling 222
        regulation of tissue remodeling 91
          regulation of bone remodeling 64
            negative regulation of bone remodeling + 20
            positive regulation of bone remodeling + 27
            regulation of bone resorption + 53
Path 2
Term Annotations click to browse term
  biological_process 19576
    biological regulation 13536
      regulation of biological process 12839
        regulation of multicellular organismal process 3427
          regulation of tissue remodeling 91
            regulation of bone remodeling 64
              negative regulation of bone remodeling + 20
              positive regulation of bone remodeling + 27
              regulation of bone resorption + 53
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.