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ONTOLOGY REPORT - ANNOTATIONS


Term:peptide-O-fucosyltransferase activity
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Accession:GO:0046922 term browser browse the term
Definition:Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
Synonyms:related_synonym: GDP-L-fucose:polypeptide fucosyltransferase activity;   GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity;   GDP-fucose protein O-fucosyltransferase activity;   GDP-fucose:polypeptide fucosyltransferase activity
 xref: EC:2.4.1.221;   MetaCyc:2.4.1.221-RXN;   reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1";   reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins"


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peptide-O-fucosyltransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pofut1 protein O-fucosyltransferase 1 ISO (PMID:15653671) UniProtKB PMID:15653671 NCBI chrNW_004955422:28,809,901...28,833,186
Ensembl chrNW_004955422:28,809,901...28,833,186
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G Pofut2 protein O-fucosyltransferase 2 ISO (PMID:22588082) UniProtKB PMID:22588082 NCBI chrNW_004955407:41,972,833...41,984,095
Ensembl chrNW_004955407:41,972,717...41,984,095
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Term paths to the root
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Term Annotations click to browse term
  molecular_function 13908
    catalytic activity 3530
      catalytic activity, acting on a protein 1487
        peptide-O-fucosyltransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 13908
    catalytic activity 3530
      transferase activity 1571
        transferase activity, transferring glycosyl groups 189
          transferase activity, transferring hexosyl groups 127
            fucosyltransferase activity 9
              peptide-O-fucosyltransferase activity 2
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