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Term:peptide-O-fucosyltransferase activity
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Accession:GO:0046922 term browser browse the term
Definition:Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
Synonyms:related_synonym: GDP-L-fucose:polypeptide fucosyltransferase activity;   GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity;   GDP-fucose protein O-fucosyltransferase activity;   GDP-fucose:polypeptide fucosyltransferase activity
 xref: EC:;   MetaCyc:;   reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1";   reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins"

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peptide-O-fucosyltransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POFUT1 protein O-fucosyltransferase 1 IEA UniProt GO_REF:0000003 NCBI chr24:21,608,905...21,636,084
Ensembl chr24:21,608,899...21,632,979
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G POFUT2 protein O-fucosyltransferase 2 IBA
(PMID:21873635) GO_Central
PMID:21873635 GO_REF:0000003 NCBI chr31:38,813,252...38,821,656
Ensembl chr31:38,813,255...38,818,734
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17054
    catalytic activity 5414
      catalytic activity, acting on a protein 2190
        peptide-O-fucosyltransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 17054
    catalytic activity 5414
      transferase activity 2174
        transferase activity, transferring glycosyl groups 275
          transferase activity, transferring hexosyl groups 190
            fucosyltransferase activity 13
              peptide-O-fucosyltransferase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.