Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:peptide-O-fucosyltransferase activity
go back to main search page
Accession:GO:0046922 term browser browse the term
Definition:Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
Synonyms:related_synonym: GDP-L-fucose:polypeptide fucosyltransferase activity;   GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity;   GDP-fucose protein O-fucosyltransferase activity;   GDP-fucose:polypeptide fucosyltransferase activity
 xref: EC:;   MetaCyc:;   reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1";   reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins"

show annotations for term's descendants           Sort by:
peptide-O-fucosyltransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pofut1 protein O-fucosyltransferase 1 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:153,241,532...153,271,029
Ensembl chr 2:153,241,533...153,270,247
JBrowse link
G Pofut2 protein O-fucosyltransferase 2 ISO
(MGI:6201960|PMID:21873635) MGI
PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:6201960 NCBI chr10:77,259,081...77,269,586
Ensembl chr10:77,259,218...77,269,575
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 23090
    catalytic activity 5756
      catalytic activity, acting on a protein 2291
        peptide-O-fucosyltransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 23090
    catalytic activity 5756
      transferase activity 2268
        transferase activity, transferring glycosyl groups 277
          transferase activity, transferring hexosyl groups 204
            fucosyltransferase activity 11
              peptide-O-fucosyltransferase activity 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.