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Term:peptide-O-fucosyltransferase activity
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Accession:GO:0046922 term browser browse the term
Definition:Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
Synonyms:related_synonym: GDP-L-fucose:polypeptide fucosyltransferase activity;   GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity;   GDP-fucose protein O-fucosyltransferase activity;   GDP-fucose:polypeptide fucosyltransferase activity
 xref: EC:;   MetaCyc:;   reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1";   reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins"

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peptide-O-fucosyltransferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pofut1 protein O-fucosyltransferase 1 ISO (PMID:15653671) UniProtKB PMID:15653671 NCBI chrNW_004936485:19,111,704...19,137,689 JBrowse link
G Pofut2 protein O-fucosyltransferase 2 ISO (PMID:22588082) UniProtKB PMID:22588082 NCBI chrNW_004936778:1,024,066...1,036,365 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 14080
    catalytic activity 3557
      catalytic activity, acting on a protein 1498
        peptide-O-fucosyltransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 14080
    catalytic activity 3557
      transferase activity 1576
        transferase activity, transferring glycosyl groups 189
          transferase activity, transferring hexosyl groups 126
            fucosyltransferase activity 8
              peptide-O-fucosyltransferase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.