Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body biosynthetic process
go back to main search page
Accession:GO:0046951 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
Synonyms:exact_synonym: ketone body anabolism;   ketone body biosynthesis;   ketone body formation;   ketone body synthesis


show annotations for term's descendants           Sort by:
 
ketone body biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase IDA
IBA
ISO
PMID:21873635
(PMID:22847177), (PMID:22865860), (PMID:9200711)
RGD PMID:9200711, PMID:22847177, PMID:22865860, PMID:2573547, PMID:21873635 RGD:1599519, RGD:13792537 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 ISS
ISO
IBA
GO_REF:0000024
(PMID:22847177), (PMID:22865860)
PMID:21873635
UniProt
RGD
PMID:22847177, PMID:22865860, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:83,069,837...83,204,778
Ensembl chr 8:83,070,545...83,205,441
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 TAS
ISO
IEP
(PMID:23751782) RGD PMID:23751782, PMID:8097464, PMID:12399220 RGD:728598, RGD:2326121 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Slc27a5 solute carrier family 27 member 5 ISO
IBA
MGI:MGI:3757682 (MGI:MGI:3722951|PMID:16618416)
PMID:21873635
RGD PMID:16618416, PMID:21873635 MGI:MGI:3722951, RGD:13792537 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      biosynthetic process 6217
        cellular biosynthetic process 6052
          ketone body biosynthetic process 4
            acetoacetic acid biosynthetic process 0
            acetone biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      cellular metabolic process 11064
        generation of precursor metabolites and energy 507
          ketone body metabolic process 10
            ketone body biosynthetic process 4
              acetoacetic acid biosynthetic process 0
              acetone biosynthetic process 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.