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ONTOLOGY REPORT - ANNOTATIONS


Term:acylglycerol lipase activity
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Accession:GO:0047372 term browser browse the term
Definition:Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
Synonyms:exact_synonym: fatty acyl monoester lipase activity;   glycerol-ester acylhydrolase activity;   monoacylglycerol hydrolase activity;   monoacylglycerol lipase activity;   monoacylglycerolipase activity;   monoglyceridase activity;   monoglyceride hydrolase activity;   monoglyceride lipase activity;   monoglyceridyllipase activity
 xref: EC:3.1.1.23;   MetaCyc:3.1.1.23-RXN;   reactome:R-HSA-1482543 "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL";   reactome:R-HSA-163595 "2-acylglycerol + H2O -> glycerol + fatty acid";   reactome:R-HSA-192422 "Digestion of triacylglycerols by extracellular PTL:colipase";   reactome:R-HSA-192425 "Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase)";   reactome:R-HSA-192430 "Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase)";   reactome:R-HSA-192434 "Digestion of diacylglycerols by extracellular PTL:colipase";   reactome:R-HSA-192475 "Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2";   reactome:R-HSA-426032 "DAG is metabolized by DAGL to 2-AG";   reactome:R-HSA-426043 "2-AG hydrolysis to arachidonate by MAGL";   reactome:R-HSA-5694462 "ABHD6,12 hydrolyse 3AG"


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acylglycerol lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd1 abhydrolase domain containing 1 JBrowse link 6 26,787,807 26,792,795 RGD:13792537
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:1624291
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
RGD:1600115
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase JBrowse link 1 140,998,240 141,087,405 RGD:1624291
RGD:13792537
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:13792537
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase JBrowse link 15 18,647,903 18,695,133 RGD:1624291
RGD:13792537
RGD:1600115
G Faah fatty acid amide hydrolase JBrowse link 5 134,852,899 134,872,095 RGD:1624291
RGD:14397564
G Faahl fatty-acid amide hydrolase-like JBrowse link 5 134,330,204 134,349,400 RGD:1624291
RGD:14397564
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308779
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:1581872
G Mgll monoglyceride lipase JBrowse link 4 120,671,436 120,773,458 RGD:1600115
RGD:13792537
RGD:1624291
RGD:14397564
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:1624291
RGD:1600115

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  molecular_function 19527
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          carboxylic ester hydrolase activity 156
            acylglycerol lipase activity 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.