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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent phospholipase A2 activity
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Accession:GO:0047498 term browser browse the term
Definition:Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
Synonyms:narrow_synonym: calcium-dependent cytosolic phospholipase A2 activity;   calcium-dependent secreted phospholipase A2 activity
 xref: reactome:R-HSA-111883 "Hydrolysis of phosphatidylcholine"


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calcium-dependent phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gm28042 predicted gene, 28042 JBrowse link 2 120,027,483 120,043,033 RGD:2290270
G Oc90 otoconin 90 JBrowse link 15 65,876,050 65,912,411 RGD:2290270
G Pla2g1b phospholipase A2, group IB, pancreas JBrowse link 5 115,466,142 115,474,722 RGD:2290270
G Pla2g2c phospholipase A2, group IIC JBrowse link 4 138,725,325 138,744,575 RGD:2290270
G Pla2g2d phospholipase A2, group IID JBrowse link 4 138,775,735 138,782,052 RGD:2290270
G Pla2g2e phospholipase A2, group IIE JBrowse link 4 138,877,911 138,882,817 RGD:2290270
G Pla2g2f phospholipase A2, group IIF JBrowse link 4 138,750,533 138,757,598 RGD:2290270
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) JBrowse link 1 149,829,618 149,961,290 RGD:2290270
G Pla2g4b phospholipase A2, group IVB (cytosolic) JBrowse link 2 120,033,433 120,043,033 RGD:2290270
G Pla2g4c phospholipase A2, group IVC (cytosolic, calcium-independent) JBrowse link 7 13,311,507 13,360,674 RGD:2290270
G Pla2g4d phospholipase A2, group IVD JBrowse link 2 120,265,866 120,289,069 RGD:2290270
G Pla2g4e phospholipase A2, group IVE JBrowse link 2 120,166,412 120,245,630 RGD:2290270
G Pla2g4f phospholipase A2, group IVF JBrowse link 2 120,299,952 120,314,165 RGD:2290270
G Pla2g5 phospholipase A2, group V JBrowse link 4 138,799,247 138,863,562 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 22373
    catalytic activity 5687
      hydrolase activity 2469
        hydrolase activity, acting on ester bonds 748
          carboxylic ester hydrolase activity 160
            phospholipase A2 activity 30
              calcium-dependent phospholipase A2 activity 14
Path 2
Term Annotations click to browse term
  molecular_function 22373
    catalytic activity 5687
      hydrolase activity 2469
        hydrolase activity, acting on ester bonds 748
          lipase activity 119
            phospholipase activity 88
              phospholipase A2 activity 30
                calcium-dependent phospholipase A2 activity 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.