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ONTOLOGY REPORT - ANNOTATIONS


Term:embryonic eye morphogenesis
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Accession:GO:0048048 term browser browse the term
Definition:The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.


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embryonic eye morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO (MGI:3608158|PMID:16207763), (MGI:3624188|PMID:16611695) MGI PMID:16207763, PMID:16611695 MGI:3608158, MGI:3624188 NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO (MGI:3608158|PMID:16207763), (MGI:3624188|PMID:16611695)
(MGI:3624188|PMID:16611695)
MGI PMID:16207763, PMID:16611695 MGI:3608158, MGI:3624188 NCBI chr15:79,603,893...79,640,866
Ensembl chr15:98,891,770...98,928,396
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 ISO (PMID:25406291) UniProtKB PMID:25406291 NCBI chr2A:56,017,678...56,076,059
Ensembl chr2A:57,155,000...57,212,500
JBrowse link
G FBN1 fibrillin 1 ISO (PMID:25406291) UniProtKB PMID:25406291 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G FBN2 fibrillin 2 ISO (PMID:25406291) UniProtKB PMID:25406291 NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711
JBrowse link
G FOXL2 forkhead box L2 ISO (MGI:3043431|PMID:15056605) MGI PMID:15056605 MGI:3043431 NCBI chr 3:135,968,040...135,980,063 JBrowse link
G MFAP2 microfibril associated protein 2 ISO (PMID:25406291) UniProtKB PMID:25406291 NCBI chr 1:15,918,209...15,924,388 JBrowse link
G RARB retinoic acid receptor beta ISO (MGI:3608158|PMID:16207763) MGI PMID:16207763 MGI:3608158 NCBI chr 3:24,729,220...25,499,187
Ensembl chr 3:25,660,922...25,833,297
JBrowse link
G RARG retinoic acid receptor gamma ISO (MGI:3608158|PMID:16207763) MGI PMID:16207763 MGI:3608158 NCBI chr12:35,521,276...35,542,814
Ensembl chr12:36,303,359...36,325,111
JBrowse link
G VAX2 ventral anterior homeobox 2 ISO (MGI:2157790|PMID:11830579)
(MGI:1349226|PMID:10595508)
MGI PMID:10595508, PMID:11830579 MGI:1349226, MGI:2157790 NCBI chr2A:70,964,829...70,997,702
Ensembl chr2A:72,078,829...72,111,463
JBrowse link
closure of optic fissure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHACTR4 phosphatase and actin regulator 4 ISO (MGI:3719969|PMID:17609112) UniProt PMID:17609112 MGI:3719969 NCBI chr 1:27,634,440...27,768,139
Ensembl chr 1:28,741,081...28,794,870
JBrowse link
G SOX11 SRY-box transcription factor 11 ISO (MGI:3797299|PMID:18423449) UniProt PMID:18423449 MGI:3797299 NCBI chr2A:5,699,738...5,711,210 JBrowse link
embryonic camera-type eye formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STRA6 signaling receptor and transporter of retinol STRA6 ISO (PMID:17273977) DFLAT PMID:17273977 NCBI chr15:53,117,891...53,150,790
Ensembl chr15:72,741,482...72,770,876
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 ISO (PMID:17070479) BHF-UCL PMID:17070479 NCBI chr 7:19,761,041...19,765,665 JBrowse link
embryonic camera-type eye morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 ISO (MGI:1332362|PMID:10049573) MGI PMID:10049573 MGI:1332362 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (MGI:3807101|PMID:18653562) MGI PMID:18653562 MGI:3807101 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G FOXF2 forkhead box F2 ISO (MGI:5297296|PMID:22022403) BHF-UCL PMID:22022403 MGI:5297296 NCBI chr 6:1,209,899...1,215,970 JBrowse link
G FZD5 frizzled class receptor 5 ISO (MGI:3826935|PMID:18832390) CACAO PMID:18832390 MGI:3826935 NCBI chr2B:95,003,246...95,010,577
Ensembl chr2B:213,133,017...213,134,774
JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 ISO (MGI:4818711|PMID:20579985) DFLAT PMID:20579985 MGI:4818711 NCBI chr 1:88,579,603...88,627,988
Ensembl chr 1:123,633,134...123,677,714
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 ISO (MGI:4818711|PMID:20579985) DFLAT PMID:20579985 MGI:4818711 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G IFT172 intraflagellar transport 172 ISO (MGI:6094959|PMID:28778798) MGI PMID:28778798 MGI:6094959 NCBI chr2A:27,448,139...27,492,302
Ensembl chr2A:27,536,534...27,580,406
JBrowse link
G IHH Indian hedgehog signaling molecule ISO (MGI:3807419|PMID:18582859) MGI PMID:18582859 MGI:3807419 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506
JBrowse link
G KDM2B lysine demethylase 2B ISO (MGI:4949568|PMID:21220025) BHF-UCL PMID:21220025 MGI:4949568 NCBI chr12:119,027,633...119,183,779
Ensembl chr12:122,401,296...122,555,246
JBrowse link
G LOC100990238 intraflagellar transport protein 122 homolog ISO (MGI:6094959|PMID:28778798) MGI PMID:28778798 MGI:6094959 NCBI chr 3:126,498,018...126,578,211
Ensembl chr 3:133,851,433...133,930,117
JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:3823171|PMID:18985738)
(MGI:4413396|PMID:19653321)
MGI PMID:18985738, PMID:19653321 MGI:3823171, MGI:4413396 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G PAX6 paired box 6 ISO (MGI:3807101|PMID:18653562) MGI PMID:18653562 MGI:3807101 NCBI chr11:31,753,190...31,782,225 JBrowse link
G SP1 Sp1 transcription factor ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr12:35,338,492...35,374,462
Ensembl chr12:36,127,681...36,158,356
JBrowse link
G SP3 Sp3 transcription factor ISO (MGI:3717030|PMID:17584888) MGI PMID:17584888 MGI:3717030 NCBI chr2B:61,185,975...61,243,155
Ensembl chr2B:178,639,677...178,692,848
JBrowse link
G TBX2 T-box transcription factor 2 ISO (MGI:3487212|PMID:15459098) BHF-UCL PMID:15459098 MGI:3487212 NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189
JBrowse link
G TFAP2A transcription factor AP-2 alpha ISO (MGI:1313057|PMID:9811866) MGI PMID:9811866 MGI:1313057 NCBI chr 6:10,237,834...10,260,843 JBrowse link
G TH tyrosine hydroxylase ISO (MGI:3617102|PMID:16445854) BHF-UCL PMID:16445854 MGI:3617102 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 ISO (MGI:3790562|PMID:18436818) MGI PMID:18436818 MGI:3790562 NCBI chr10:31,449,202...31,659,534
Ensembl chr10:32,046,491...32,253,550
JBrowse link
optic cup formation involved in camera-type eye development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARID1A AT-rich interaction domain 1A ISO (MGI:5466629|PMID:23129809) MGI PMID:23129809 MGI:5466629 NCBI chr 1:25,960,868...26,047,057
Ensembl chr 1:27,018,616...27,103,239
JBrowse link
optic cup morphogenesis involved in camera-type eye development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO (MGI:3624188|PMID:16611695) MGI PMID:16611695 MGI:3624188 NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO (MGI:3624188|PMID:16611695) MGI PMID:16611695 MGI:3624188 NCBI chr15:79,603,893...79,640,866
Ensembl chr15:98,891,770...98,928,396
JBrowse link
G PAX2 paired box 2 ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028
JBrowse link
optic cup structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFAP2A transcription factor AP-2 alpha ISO (MGI:4439459|PMID:20150232) UniProt PMID:20150232 MGI:4439459 NCBI chr 6:10,237,834...10,260,843 JBrowse link
optic placode formation involved in camera-type eye formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FRS2 fibroblast growth factor receptor substrate 2 ISO (MGI:3513737|PMID:15569927) MGI PMID:15569927 MGI:3513737 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293
JBrowse link
G PROX1 prospero homeobox 1 ISO (PMID:11850194) BHF-UCL PMID:11850194 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763
JBrowse link
optic vesicle morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIX3 SIX homeobox 3 ISO (MGI:2136715|PMID:11458394) UniProt PMID:11458394 MGI:2136715 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G TFAP2A transcription factor AP-2 alpha ISO (MGI:4439459|PMID:20150232) UniProt PMID:20150232 MGI:4439459 NCBI chr 6:10,237,834...10,260,843 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure morphogenesis 2581
        animal organ morphogenesis 1040
          embryonic organ morphogenesis 316
            embryonic eye morphogenesis 37
              embryonic camera-type eye morphogenesis + 29
Path 2
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure development 5452
        multicellular organism development 4984
          system development 4688
            animal organ development 3618
              sensory organ development 646
                eye development 421
                  eye morphogenesis 171
                    embryonic eye morphogenesis 37
                      embryonic camera-type eye morphogenesis + 29
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.