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ONTOLOGY REPORT - ANNOTATIONS


Term:chromatin-mediated maintenance of transcription
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Accession:GO:0048096 term browser browse the term
Definition:Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.
Comment:Note that this process is the opposite of chromatin silencing. This regulation is exemplified by members of the trithorax group, which maintain the active state of homeotic gene transcription.


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chromatin-mediated maintenance of transcription term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdca4 cell division cycle associated 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:137,396,133...137,421,283
Ensembl chr 6:137,396,140...137,421,283
JBrowse link
G Chek1 checkpoint kinase 1 ISO
ISS
(MGI:MGI:5294291|PMID:18243098)
GO_REF:0000024
RGD
UniProt
PMID:18243098 GO_REF:0000024, MGI:MGI:5294291 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:5428344|PMID:22723415)
GO_REF:0000107
RGD
Ensembl
PMID:22723415 GO_REF:0000107, MGI:MGI:5428344 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Elof1 elongation factor 1 homolog IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:23,125,987...23,130,980
Ensembl chr 8:23,125,988...23,130,877
JBrowse link
G LOC103693776 zinc finger MIZ domain-containing protein 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,514,157...86,530,701
Ensembl chr14:86,514,214...86,530,701
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP PMID:12917342 UniProt PMID:12917342 RGD:8553888 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like ISO MGI:MGI:5437740 (MGI:MGI:5688228|PMID:26134869) RGD PMID:26134869 MGI:MGI:5688228 NCBI chr 3:160,410,733...160,447,073
Ensembl chr 3:160,410,757...160,444,940
JBrowse link
G Padi2 peptidyl arginine deiminase 2 IEA
ISO
GO_REF:0000107
(PMID:22853951)
Ensembl
RGD
PMID:22853951 GO_REF:0000107 NCBI chr 5:159,428,479...159,471,113
Ensembl chr 5:159,428,515...159,471,144
JBrowse link
G Sertad1 SERTA domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sertad2 SERTA domain containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:104,786,649...104,890,022
Ensembl chr14:104,821,215...104,886,197
JBrowse link
G Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 ISO (PMID:12917342) RGD PMID:12917342 NCBI chr 7:141,355,623...141,366,725
Ensembl chr 7:141,355,994...141,366,732
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,645,875...86,662,419
Ensembl chr14:86,652,365...86,661,441
JBrowse link
positive regulation of chromatin-mediated maintenance of transcription term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:5428344|PMID:22723415)
GO_REF:0000107
RGD
Ensembl
PMID:22723415 GO_REF:0000107, MGI:MGI:5428344 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          chromatin organization 847
            chromatin organization involved in regulation of transcription 143
              chromatin-mediated maintenance of transcription 13
                negative regulation of chromatin-mediated maintenance of transcription 0
                positive regulation of chromatin-mediated maintenance of transcription 1
                regulation of chromatin-mediated maintenance of transcription + 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              RNA metabolic process 4470
                regulation of RNA metabolic process 3616
                  positive regulation of RNA metabolic process 1857
                    positive regulation of RNA biosynthetic process 1759
                      positive regulation of nucleic acid-templated transcription 1758
                        positive regulation of transcription, DNA-templated 1698
                          chromatin-mediated maintenance of transcription 13
                            negative regulation of chromatin-mediated maintenance of transcription 0
                            positive regulation of chromatin-mediated maintenance of transcription 1
                            regulation of chromatin-mediated maintenance of transcription + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.