Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:response to pain
go back to main search page
Accession:GO:0048265 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
Synonyms:exact_synonym: physiological response to pain
 alt_id: GO:0048267


show annotations for term's descendants           Sort by:
 
response to pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO MGI:MGI:1856210 (MGI:MGI:2153687|PMID:11718712) RGD PMID:11718712 MGI:MGI:2153687 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B ISO
IEA
(MGI:MGI:3607758|PMID:12074836)
GO_REF:0000107
RGD
Ensembl
PMID:12074836 GO_REF:0000107, MGI:MGI:3607758 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E ISO (MGI:MGI:3607758|PMID:12074836) RGD PMID:12074836 MGI:MGI:3607758 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO MGI:MGI:2148771 (MGI:MGI:1335275|PMID:10208559), (MGI:MGI:1933070|PMID:11276224) RGD PMID:10208559, PMID:11276224 MGI:MGI:1335275, MGI:MGI:1933070 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Comt catechol-O-methyltransferase IMP RGD PMID:17084978 RGD:2289747 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crh corticotropin releasing hormone IEP RGD PMID:21463663 RGD:5490545 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Dbh dopamine beta-hydroxylase ISO
IEA
MGI:MGI:1857556 (MGI:MGI:2157273|PMID:11805341)
GO_REF:0000107
RGD
Ensembl
PMID:11805341 GO_REF:0000107, MGI:MGI:2157273 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:12847519 RGD:1581889 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Gch1 GTP cyclohydrolase 1 IDA PMID:17057711 UniProt PMID:17057711 RGD:8554553 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gja4 gap junction protein, alpha 4 IEP RGD PMID:11978404 RGD:728686 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 ISO MGI:MGI:2179103 (MGI:MGI:2158115|PMID:11792319) RGD PMID:11792319 MGI:MGI:2158115 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Nmur2 neuromedin U receptor 2 ISO MGI:MGI:3701426 (MGI:MGI:3697042|PMID:17030627) RGD PMID:17030627 MGI:MGI:3697042 NCBI chr10:41,392,663...41,408,518
Ensembl chr10:41,392,666...41,408,518
JBrowse link
G Prkcg protein kinase C, gamma ISO
ISS
(MGI:MGI:1097759|PMID:9323205)
GO_REF:0000024
RGD
UniProt
PMID:9323205 GO_REF:0000024, MGI:MGI:1097759 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Reln reelin ISO
ISS
IEA
MGI:MGI:1856398 (MGI:MGI:3625412|PMID:16580148)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:16580148 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3625412 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Ret ret proto-oncogene ISO (MGI:MGI:4441221|PMID:20237269) RGD PMID:20237269 MGI:MGI:4441221 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Slc6a2 solute carrier family 6 member 2 ISO (MGI:MGI:2157273|PMID:11805341) RGD PMID:11805341 MGI:MGI:2157273 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Tac1 tachykinin, precursor 1 ISO (MGI:MGI:2157273|PMID:11805341) RGD PMID:11805341 MGI:MGI:2157273 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 ISO (MGI:MGI:2157273|PMID:11805341) RGD PMID:11805341 MGI:MGI:2157273 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IEA
ISO
GO_REF:0000107
MGI:MGI:3624810 (MGI:MGI:3623714|PMID:16630838), (MGI:MGI:3790902|PMID:18272293), (MGI:MGI:3794274|PMID:18297068)
Ensembl
RGD
PMID:16630838, PMID:18272293, PMID:18297068 GO_REF:0000107, MGI:MGI:3623714, MGI:MGI:3790902, MGI:MGI:3794274 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO MGI:MGI:1934023 (MGI:MGI:3790902|PMID:18272293), (MGI:MGI:3794274|PMID:18297068) RGD PMID:18272293, PMID:18297068 MGI:MGI:3790902, MGI:MGI:3794274 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Tspo translocator protein IEP RGD PMID:19555675 RGD:2317138 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Ucn urocortin IEP RGD PMID:21463663 RGD:5490545 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
behavioral response to formalin induced pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kalrn kalirin, RhoGEF kinase ISO MGI:MGI:3831288 (MGI:MGI:5645427|PMID:25865668) RGD PMID:25865668 MGI:MGI:5645427 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO (MGI:MGI:5571523|PMID:24760869) RGD PMID:24760869 MGI:MGI:5571523 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G P2rx3 purinergic receptor P2X 3 IMP RGD PMID:24120766 RGD:10043614 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
behavioral response to pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO
IEA
MGI:MGI:2180190 (MGI:MGI:3664669|PMID:16890369)
GO_REF:0000107
RGD
Ensembl
PMID:16890369 GO_REF:0000107, MGI:MGI:3664669 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E ISO MGI:MGI:2179732 (MGI:MGI:1858676|PMID:10801976) RGD PMID:10801976 MGI:MGI:1858676 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Capn2 calpain 2 IDA RGD PMID:25150005 RGD:13792585 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:17550594 RGD:1626231 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Git2 GIT ArfGAP 2 ISO MGI:MGI:3762635 (MGI:MGI:5506968|PMID:23870131) RGD PMID:23870131 MGI:MGI:5506968 NCBI chr12:47,590,110...47,630,991
Ensembl chr12:47,590,154...47,631,119
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 ISO MGI:MGI:2176347 (MGI:MGI:3577154|PMID:15673679) RGD PMID:15673679 MGI:MGI:3577154 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO MGI:MGI:1928295 (MGI:MGI:3610653|PMID:11711849) RGD PMID:11711849 MGI:MGI:3610653 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:16098671 RGD:6480679 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 ISO MGI:MGI:2679303 (MGI:MGI:2677561|PMID:14534243) RGD PMID:14534243 MGI:MGI:2677561 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Lpar5 lysophosphatidic acid receptor 5 ISO
IBA
MGI:MGI:5431493 (MGI:MGI:5429492|PMID:22461625)
PMID:21873635
RGD PMID:22461625, PMID:21873635 MGI:MGI:5429492, RGD:13792537 NCBI chr 4:157,581,000...157,596,454
Ensembl chr 4:157,594,436...157,595,972
JBrowse link
G Osm oncostatin M ISO MGI:MGI:3574987 (MGI:MGI:3574134|PMID:14985435) RGD PMID:14985435 MGI:MGI:3574134 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G P2rx2 purinergic receptor P2X 2 ISO
IEA
MGI:MGI:1097160|MGI:MGI:2687349 (MGI:MGI:3656422|PMID:15961431)
GO_REF:0000107
RGD
Ensembl
PMID:15961431 GO_REF:0000107, MGI:MGI:3656422 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P2rx3 purinergic receptor P2X 3 ISO MGI:MGI:1934019|MGI:MGI:2385840|MGI:MGI:2665170 (MGI:MGI:1926735|PMID:11069181), (MGI:MGI:1926736|PMID:11069182), (MGI:MGI:3656422|PMID:15961431) RGD PMID:11069181, PMID:11069182, PMID:15961431 MGI:MGI:1926735, MGI:MGI:1926736, MGI:MGI:3656422 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2rx4 purinergic receptor P2X 4 IMP PMID:12917686 ARUK-UCL PMID:12917686 RGD:13673840 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels ISO MGI:MGI:3834636 (MGI:MGI:3834285|PMID:18455988) RGD PMID:18455988 MGI:MGI:3834285 NCBI chr10:53,466,870...53,485,096
Ensembl chr10:53,466,870...53,481,770
JBrowse link
G Runx1 RUNX family transcription factor 1 ISO (MGI:MGI:3619829|PMID:16446141) RGD PMID:16446141 MGI:MGI:3619829 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 ISO MGI:MGI:3053098 (MGI:MGI:3052623|PMID:15314237) RGD PMID:15314237 MGI:MGI:3052623 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18407414 RGD:2304276 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Thbs1 thrombospondin 1 ISO (MGI:MGI:5516179|PMID:22745497) RGD PMID:22745497 MGI:MGI:5516179 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thbs4 thrombospondin 4 IMP
ISO
IEA
PMID:22745497
(MGI:MGI:5516179|PMID:22745497)
GO_REF:0000107
RGD
Ensembl
PMID:22745497, PMID:22745497 GO_REF:0000107, MGI:MGI:5516179, RGD:8553360 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO MGI:MGI:1934023 (MGI:MGI:3763480|PMID:17767493), (MGI:MGI:3778264|PMID:18272658), (MGI:MGI:3834285|PMID:18455988) RGD PMID:17767493, PMID:18272658, PMID:18455988 MGI:MGI:3763480, MGI:MGI:3778264, MGI:MGI:3834285 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Tspo translocator protein IMP RGD PMID:19555675 RGD:2317138 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 ISO MGI:MGI:3809230 (MGI:MGI:3849094|PMID:19279005) RGD PMID:19279005 MGI:MGI:3849094 NCBI chr 5:173,216,737...173,221,923
Ensembl chr 5:173,216,741...173,222,440
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    multicellular organismal process 9055
      multicellular organismal response to stress 107
        response to pain 41
          behavioral response to pain + 25
Path 2
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      response to stress 4059
        multicellular organismal response to stress 107
          response to pain 41
            behavioral response to pain + 25
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.