Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:response to pain
go back to main search page
Accession:GO:0048265 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
Synonyms:exact_synonym: physiological response to pain
 alt_id: GO:0048267


show annotations for term's descendants           Sort by:
 
response to pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO (MGI:MGI:2153687|PMID:11718712) MGI PMID:11718712 MGI:MGI:2153687 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B IEA Ensembl GO_REF:0000107 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO (MGI:MGI:3607758|PMID:12074836) MGI PMID:12074836 MGI:MGI:3607758 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422
JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:17084978 RGD:2289747 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:21463663 RGD:5490545 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 ISO (MGI:MGI:1335275|PMID:10208559), (MGI:MGI:1933070|PMID:11276224) MGI PMID:10208559, PMID:11276224 MGI:MGI:1335275, MGI:MGI:1933070 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G DBH dopamine beta-hydroxylase IEA Ensembl GO_REF:0000107 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130
JBrowse link
G EDNRB endothelin receptor type B ISO RGD PMID:12847519 RGD:1581889 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587
JBrowse link
G GCH1 GTP cyclohydrolase 1 ISO PMID:17057711 UniProt PMID:17057711 RGD:8554553 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156
JBrowse link
G GJA4 gap junction protein alpha 4 ISO RGD PMID:11978404 RGD:728686 NCBI chr15:7,167,665...7,170,388 JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 ISO (MGI:MGI:2158115|PMID:11792319) MGI PMID:11792319 MGI:MGI:2158115 NCBI chr17:34,725,433...34,808,429 JBrowse link
G LOC484316 protein kinase C gamma type IEA Ensembl GO_REF:0000107 NCBI chr 1:103,495,013...103,512,465 JBrowse link
G NMUR2 neuromedin U receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:56,994,731...57,018,429
Ensembl chr 4:56,994,886...57,008,384
JBrowse link
G PRKCG protein kinase C gamma IEA Ensembl GO_REF:0000107 NCBI chr 1:103,295,110...103,312,562 JBrowse link
G RELN reelin IEA Ensembl GO_REF:0000107 NCBI chr18:16,275,822...16,773,875
Ensembl chr18:16,275,837...16,773,875
JBrowse link
G RET ret proto-oncogene IEA Ensembl GO_REF:0000107 NCBI chr28:3,946,132...3,995,505
Ensembl chr28:3,947,232...3,994,210
JBrowse link
G SLC6A2 solute carrier family 6 member 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:60,319,304...60,362,532
Ensembl chr 2:60,318,999...60,363,120
JBrowse link
G TAC1 tachykinin precursor 1 IEA Ensembl GO_REF:0000107 NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258
JBrowse link
G TACR1 tachykinin receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 IEA Ensembl GO_REF:0000107 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO (MGI:MGI:3790902|PMID:18272293)
(MGI:MGI:3794274|PMID:18297068)
MGI PMID:18272293, PMID:18297068 MGI:MGI:3790902, MGI:MGI:3794274 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926
JBrowse link
G TSPO translocator protein ISO RGD PMID:19555675 RGD:2317138 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297
JBrowse link
G UCN urocortin ISO RGD PMID:21463663 RGD:5490545 NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312
JBrowse link
behavioral response to formalin induced pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KALRN kalirin RhoGEF kinase ISO (MGI:MGI:5645427|PMID:25865668) MGI PMID:25865668 MGI:MGI:5645427 NCBI chr33:27,161,403...27,752,891
Ensembl chr33:27,161,504...27,746,497
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288
JBrowse link
G P2RX3 purinergic receptor P2X 3 ISO RGD PMID:24120766 RGD:10043614 NCBI chr18:38,773,930...38,801,217
Ensembl chr18:38,772,529...38,802,057
JBrowse link
behavioral response to pain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A IEA Ensembl GO_REF:0000107 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO (MGI:MGI:1858676|PMID:10801976) MGI PMID:10801976 MGI:MGI:1858676 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422
JBrowse link
G CAPN2 calpain 2 ISO RGD PMID:25150005 RGD:13792585 NCBI chr 7:40,333,379...40,367,158
Ensembl chr 7:40,334,012...40,377,037
JBrowse link
G GIT2 GIT ArfGAP 2 ISO (MGI:MGI:5506968|PMID:23870131) MGI PMID:23870131 MGI:MGI:5506968 NCBI chr26:17,170,651...17,217,634
Ensembl chr26:17,170,680...17,214,631
JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 ISO (MGI:MGI:3577154|PMID:15673679) MGI PMID:15673679 MGI:MGI:3577154 NCBI chr31:24,477,319...24,839,502
Ensembl chr31:24,478,696...24,839,434
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO (MGI:MGI:3610653|PMID:11711849) MGI PMID:11711849 MGI:MGI:3610653 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:16098671 RGD:6480679 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191
JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 ISO (MGI:MGI:2677561|PMID:14534243) MGI PMID:14534243 MGI:MGI:2677561 NCBI chr17:34,725,433...34,808,429 JBrowse link
G LOC610380 corticotropin-releasing factor receptor 1 ISO RGD PMID:17550594 RGD:1626231 NCBI chr 9:9,708,696...9,763,281 JBrowse link
G LPAR5 lysophosphatidic acid receptor 5 ISO (MGI:MGI:5429492|PMID:22461625) MGI PMID:22461625 MGI:MGI:5429492 NCBI chr27:38,389,803...38,402,412 JBrowse link
G OSM oncostatin M ISO (MGI:MGI:3574134|PMID:14985435) MGI PMID:14985435 MGI:MGI:3574134 NCBI chr26:23,421,787...23,439,332
Ensembl chr26:23,421,787...23,426,036
JBrowse link
G P2RX2 purinergic receptor P2X 2 IEA Ensembl GO_REF:0000107 NCBI chr26:480,370...485,527
Ensembl chr26:482,425...485,502
JBrowse link
G P2RX3 purinergic receptor P2X 3 IEA Ensembl GO_REF:0000107 NCBI chr18:38,773,930...38,801,217
Ensembl chr18:38,772,529...38,802,057
JBrowse link
G P2RX4 purinergic receptor P2X 4 ISO PMID:12917686 ARUK-UCL PMID:12917686 RGD:13673840 NCBI chr26:7,897,528...7,914,279
Ensembl chr26:7,898,015...7,914,234
JBrowse link
G PIRT phosphoinositide interacting regulator of transient receptor potential channels IEA Ensembl GO_REF:0000107 NCBI chr 5:35,085,480...35,095,752
Ensembl chr 5:35,086,173...35,086,589
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO (MGI:MGI:3619829|PMID:16446141) MGI PMID:16446141 MGI:MGI:3619829 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G SCN9A sodium voltage-gated channel alpha subunit 9 IEA Ensembl
InterPro
GO_REF:0000002, GO_REF:0000107 NCBI chr36:11,287,358...11,382,897
Ensembl chr36:11,290,625...11,383,255
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:18407414 RGD:2304276 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971
JBrowse link
G THBS1 thrombospondin 1 ISO (MGI:MGI:5516179|PMID:22745497) UniProtKB PMID:22745497 MGI:MGI:5516179 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
G THBS4 thrombospondin 4 ISO (MGI:MGI:5516179|PMID:22745497) UniProtKB
UniProt
PMID:22745497 MGI:MGI:5516179, RGD:8553360 NCBI chr 3:26,945,001...26,982,224
Ensembl chr 3:26,945,081...26,988,597
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926
JBrowse link
G TSPO translocator protein ISO RGD PMID:19555675 RGD:2317138 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297
JBrowse link
G VWA1 von Willebrand factor A domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:56,578,256...56,583,552
Ensembl chr 5:56,578,297...56,582,502
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    multicellular organismal process 7627
      multicellular organismal response to stress 106
        response to pain 42
          behavioral response to pain + 25
Path 2
Term Annotations click to browse term
  biological_process 16187
    response to stimulus 8560
      response to stress 3628
        multicellular organismal response to stress 106
          response to pain 42
            behavioral response to pain + 25
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.