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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of isotype switching to IgE isotypes
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Accession:GO:0048294 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms:exact_synonym: down regulation of isotype switching to IgE isotypes;   downregulation of isotype switching to IgE isotypes;   negative regulation of class switch recombination to IgE isotypes;   negative regulation of class switching to IgE isotypes;   negative regulation of isotype switch recombination to IgE isotypes
 narrow_synonym: inhibition of isotype switching to IgE isotypes


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negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6 transcription repressor JBrowse link NW_004955420 19,998,960 20,021,200 RGD:9068941
G Foxp3 forkhead box P3 JBrowse link NW_004955543 731,707 742,606 RGD:9068941
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link NW_004955415 11,643,846 11,666,131 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14546
    developmental process 5877
      negative regulation of developmental process 896
        negative regulation of isotype switching 5
          negative regulation of isotype switching to IgE isotypes 3
Path 2
Term Annotations click to browse term
  biological_process 14546
    metabolic process 9943
      cellular metabolic process 9374
        cellular aromatic compound metabolic process 5118
          nucleobase-containing compound metabolic process 4929
            nucleic acid metabolic process 4443
              DNA metabolic process 876
                DNA recombination 277
                  somatic cell DNA recombination 64
                    somatic diversification of immune receptors via germline recombination within a single locus 64
                      somatic recombination of immunoglobulin gene segments 52
                        somatic recombination of immunoglobulin genes involved in immune response 47
                          isotype switching 47
                            regulation of isotype switching 34
                              negative regulation of isotype switching 5
                                negative regulation of isotype switching to IgE isotypes 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.