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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of isotype switching to IgE isotypes
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Accession:GO:0048294 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms:exact_synonym: down regulation of isotype switching to IgE isotypes;   downregulation of isotype switching to IgE isotypes;   negative regulation of class switch recombination to IgE isotypes;   negative regulation of class switching to IgE isotypes;   negative regulation of isotype switch recombination to IgE isotypes
 narrow_synonym: inhibition of isotype switching to IgE isotypes


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negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 34 20,112,302 20,135,705 RGD:13508589

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Path 1
Term Annotations click to browse term
  biological_process 13644
    developmental process 3739
      negative regulation of developmental process 552
        negative regulation of isotype switching 3
          negative regulation of isotype switching to IgE isotypes 1
Path 2
Term Annotations click to browse term
  biological_process 13644
    metabolic process 8513
      cellular metabolic process 7769
        cellular aromatic compound metabolic process 4037
          nucleobase-containing compound metabolic process 3902
            nucleic acid metabolic process 3545
              DNA metabolic process 602
                DNA recombination 201
                  somatic cell DNA recombination 42
                    somatic diversification of immune receptors via germline recombination within a single locus 42
                      somatic recombination of immunoglobulin gene segments 35
                        somatic recombination of immunoglobulin genes involved in immune response 30
                          isotype switching 30
                            regulation of isotype switching 22
                              negative regulation of isotype switching 3
                                negative regulation of isotype switching to IgE isotypes 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.