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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of isotype switching to IgA isotypes
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Accession:GO:0048297 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.
Synonyms:exact_synonym: down regulation of isotype switching to IgA isotypes;   downregulation of isotype switching to IgA isotypes;   negative regulation of class switch recombination to IgA isotypes;   negative regulation of class switching to IgA isotypes;   negative regulation of isotype switch recombination to IgA isotypes
 narrow_synonym: inhibition of isotype switching to IgA isotypes


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negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291

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Path 1
Term Annotations click to browse term
  biological_process 19334
    developmental process 6638
      negative regulation of developmental process 1096
        negative regulation of isotype switching 6
          negative regulation of isotype switching to IgA isotypes 2
Path 2
Term Annotations click to browse term
  biological_process 19334
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5484
          nucleobase-containing compound metabolic process 5258
            nucleic acid metabolic process 4770
              DNA metabolic process 877
                DNA recombination 306
                  somatic cell DNA recombination 73
                    somatic diversification of immune receptors via germline recombination within a single locus 73
                      somatic recombination of immunoglobulin gene segments 60
                        somatic recombination of immunoglobulin genes involved in immune response 55
                          isotype switching 55
                            regulation of isotype switching 40
                              negative regulation of isotype switching 6
                                negative regulation of isotype switching to IgA isotypes 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.