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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of isotype switching to IgA isotypes
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Accession:GO:0048298 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
Synonyms:exact_synonym: positive regulation of class switch recombination to IgA isotypes;   positive regulation of class switching to IgA isotypes;   positive regulation of isotype switch recombination to IgA isotypes;   up regulation of isotype switching to IgA isotypes;   upregulation of isotype switching to IgA isotypes
 narrow_synonym: activation of isotype switching to IgA isotypes;   stimulation of isotype switching to IgA isotypes


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positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 14 82,119,210 82,196,501 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      positive regulation of developmental process 1603
        positive regulation of isotype switching 29
          positive regulation of isotype switching to IgA isotypes 6
Path 2
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5482
          nucleobase-containing compound metabolic process 5256
            nucleic acid metabolic process 4768
              DNA metabolic process 877
                DNA recombination 306
                  somatic cell DNA recombination 73
                    somatic diversification of immune receptors via germline recombination within a single locus 73
                      somatic recombination of immunoglobulin gene segments 60
                        somatic recombination of immunoglobulin genes involved in immune response 55
                          isotype switching 55
                            regulation of isotype switching 40
                              positive regulation of isotype switching 29
                                positive regulation of isotype switching to IgA isotypes 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.