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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of isotype switching to IgG isotypes
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Accession:GO:0048304 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: positive regulation of class switch recombination to IgG isotypes;   positive regulation of class switching to IgG isotypes;   positive regulation of isotype switch recombination to IgG isotypes;   up regulation of isotype switching to IgG isotypes;   upregulation of isotype switching to IgG isotypes
 narrow_synonym: activation of isotype switching to IgG isotypes;   stimulation of isotype switching to IgG isotypes


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positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:13508589
G IL2 interleukin 2 JBrowse link 19 17,750,780 17,756,394 RGD:13508589
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G PAXIP1 PAX interacting protein 1 JBrowse link 16 18,066,289 18,116,007 RGD:13508589
G TBX21 T-box transcription factor 21 JBrowse link 9 24,077,752 24,086,560 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14453
    developmental process 3809
      positive regulation of developmental process 811
        positive regulation of isotype switching 21
          positive regulation of isotype switching to IgG isotypes 8
Path 2
Term Annotations click to browse term
  biological_process 14453
    metabolic process 9079
      cellular metabolic process 8186
        cellular aromatic compound metabolic process 4199
          nucleobase-containing compound metabolic process 4061
            nucleic acid metabolic process 3673
              DNA metabolic process 619
                DNA recombination 209
                  somatic cell DNA recombination 46
                    somatic diversification of immune receptors via germline recombination within a single locus 46
                      somatic recombination of immunoglobulin gene segments 39
                        somatic recombination of immunoglobulin genes involved in immune response 34
                          isotype switching 34
                            regulation of isotype switching 26
                              positive regulation of isotype switching 21
                                positive regulation of isotype switching to IgG isotypes 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.