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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of isotype switching to IgG isotypes
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Accession:GO:0048304 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: positive regulation of class switch recombination to IgG isotypes;   positive regulation of class switching to IgG isotypes;   positive regulation of isotype switch recombination to IgG isotypes;   up regulation of isotype switching to IgG isotypes;   upregulation of isotype switching to IgG isotypes
 narrow_synonym: activation of isotype switching to IgG isotypes;   stimulation of isotype switching to IgG isotypes


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positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 12 42,874,705 42,920,438 RGD:14298760
G CD28 CD28 molecule JBrowse link 15 107,128,103 107,155,431 RGD:14298760
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:14298760
G IL2 interleukin 2 JBrowse link 8 101,640,938 101,645,683 RGD:14298760
G IL4 interleukin 4 JBrowse link 2 134,986,817 134,994,365 RGD:14298760
G MLH1 mutL homolog 1 JBrowse link 13 21,791,276 21,877,789 RGD:14298760
G MSH2 mutS homolog 2 JBrowse link 3 93,082,958 93,163,556 RGD:14298760
G PAXIP1 PAX interacting protein 1 JBrowse link 18 3,066,853 3,111,239 RGD:14298760
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 10 21,482,984 21,601,627 RGD:14298760
G TBX21 T-box transcription factor 21 JBrowse link 12 23,996,415 24,009,353 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15162
    developmental process 4236
      positive regulation of developmental process 940
        positive regulation of isotype switching 25
          positive regulation of isotype switching to IgG isotypes 10
Path 2
Term Annotations click to browse term
  biological_process 15162
    metabolic process 9321
      cellular metabolic process 8405
        cellular aromatic compound metabolic process 4363
          nucleobase-containing compound metabolic process 4222
            nucleic acid metabolic process 3865
              DNA metabolic process 659
                DNA recombination 229
                  somatic cell DNA recombination 53
                    somatic diversification of immune receptors via germline recombination within a single locus 53
                      somatic recombination of immunoglobulin gene segments 45
                        somatic recombination of immunoglobulin genes involved in immune response 40
                          isotype switching 40
                            regulation of isotype switching 32
                              positive regulation of isotype switching 25
                                positive regulation of isotype switching to IgG isotypes 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.