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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of isotype switching to IgG isotypes
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Accession:GO:0048304 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: positive regulation of class switch recombination to IgG isotypes;   positive regulation of class switching to IgG isotypes;   positive regulation of isotype switch recombination to IgG isotypes;   up regulation of isotype switching to IgG isotypes;   upregulation of isotype switching to IgG isotypes
 narrow_synonym: activation of isotype switching to IgG isotypes;   stimulation of isotype switching to IgG isotypes


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positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:13792537
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    developmental process 6694
      positive regulation of developmental process 1620
        positive regulation of isotype switching 30
          positive regulation of isotype switching to IgG isotypes 13
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5276
            nucleic acid metabolic process 4782
              DNA metabolic process 887
                DNA recombination 309
                  somatic cell DNA recombination 74
                    somatic diversification of immune receptors via germline recombination within a single locus 74
                      somatic recombination of immunoglobulin gene segments 61
                        somatic recombination of immunoglobulin genes involved in immune response 56
                          isotype switching 56
                            regulation of isotype switching 41
                              positive regulation of isotype switching 30
                                positive regulation of isotype switching to IgG isotypes 13
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.