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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin secretion
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Accession:GO:0048305 term browser browse the term
Definition:The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.
Synonyms:exact_synonym: antibody secretion


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immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:1624291
RGD:1600115
G Lax1 lymphocyte transmembrane adaptor 1 JBrowse link 13 50,164,563 50,175,119 RGD:1624291
G Pou2f2 POU class 2 homeobox 2 JBrowse link 1 81,966,791 82,049,116 RGD:1624291
G Tnfsf13b TNF superfamily member 13b JBrowse link 16 85,275,690 85,306,419 RGD:1624291
RGD:1600115
G Traf3ip2 Traf3 interacting protein 2 JBrowse link 20 44,679,861 44,722,874 RGD:1624291
RGD:1600115
immunoglobulin secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Pou2f2 POU class 2 homeobox 2 JBrowse link 1 81,966,791 82,049,116 RGD:1624291
negative regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Siglec10 sialic acid binding Ig-like lectin 10 JBrowse link 1 98,512,663 98,521,736 RGD:1600115
RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
positive regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:1600115
RGD:1624291
G Tnfrsf4 TNF receptor superfamily member 4 JBrowse link 5 173,447,784 173,450,474 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
G Vamp3 vesicle-associated membrane protein 3 JBrowse link 5 168,126,157 168,136,628 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:1600115
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291
RGD:1600115
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    immune system process 2631
      production of molecular mediator of immune response 361
        immunoglobulin production 258
          immunoglobulin secretion 26
            immunoglobulin secretion involved in immune response 2
            negative regulation of immunoglobulin secretion 4
            positive regulation of immunoglobulin secretion 13
            regulation of immunoglobulin secretion + 21
Path 2
Term Annotations click to browse term
  biological_process 19245
    localization 6273
      establishment of localization 4844
        transport 4705
          nitrogen compound transport 2235
            amide transport 1913
              peptide transport 1880
                protein transport 1822
                  protein secretion 651
                    immunoglobulin secretion 26
                      immunoglobulin secretion involved in immune response 2
                      negative regulation of immunoglobulin secretion 4
                      positive regulation of immunoglobulin secretion 13
                      regulation of immunoglobulin secretion + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.