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ONTOLOGY REPORT - ANNOTATIONS


Term:retinoic acid receptor signaling pathway
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Accession:GO:0048384 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: RAR signaling pathway;   retinoic acid receptor signalling pathway


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retinoic acid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn4 actinin alpha 4 ISO
ISS
(PMID:22351778)
GO_REF:0000024
RGD
UniProt
PMID:22351778 GO_REF:0000024 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 ISO MGI:MGI:1096359|MGI:MGI:1857891|MGI:MGI:2180721|MGI:MGI:2679699 (MGI:MGI:3574230|PMID:15739227), (MGI:MGI:3663954|PMID:16806149), (MGI:MGI:3703483|PMID:17067568) RGD PMID:15739227, PMID:16806149, PMID:17067568 MGI:MGI:3574230, MGI:MGI:3663954, MGI:MGI:3703483 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Crem cAMP responsive element modulator IEP RGD PMID:15725648 RGD:1582466 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO MGI:MGI:5510713 (MGI:MGI:6102264|PMID:25565927) RGD PMID:25565927 MGI:MGI:6102264 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 ISO MGI:MGI:2679699 (MGI:MGI:3703483|PMID:17067568) RGD PMID:17067568 MGI:MGI:3703483 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 ISO (MGI:MGI:3037623|PMID:15030763), (MGI:MGI:3619821|PMID:16554478), (MGI:MGI:3809313|PMID:18816858) RGD PMID:15030763, PMID:16554478, PMID:18816858 MGI:MGI:3037623, MGI:MGI:3619821, MGI:MGI:3809313 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Esrrg estrogen-related receptor gamma IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Nos2 nitric oxide synthase 2 IEP RGD PMID:15602748 RGD:1582142 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 IDA RGD PMID:7971966 RGD:61674 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Pml PML nuclear body scaffold ISO MGI:MGI:2429949 (MGI:MGI:1197798|PMID:9488655) RGD PMID:9488655 MGI:MGI:1197798 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO
ISS
(PMID:16239304)
(MGI:MGI:5447618|PMID:16239304)
GO_REF:0000024
RGD
GO_Central
PMID:16239304 GO_REF:0000024, MGI:MGI:5447618 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO
ISS
(MGI:MGI:1859633|PMID:11318877)
GO_REF:0000024
RGD
UniProt
PMID:11318877 GO_REF:0000024, MGI:MGI:1859633 NCBI chr17:86,199,623...86,201,477
Ensembl chr17:86,199,623...86,201,477
JBrowse link
G Rara retinoic acid receptor, alpha IDA
IBA
ISO
PMID:21873635
(PMID:17538076), (PMID:19917671)
RGD PMID:17538076, PMID:19917671, PMID:19100254, PMID:21873635 RGD:2314252, RGD:13792537 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:19100254, PMID:21873635 RGD:2314252, RGD:13792537 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rarg retinoic acid receptor, gamma IMP
IBA
ISO
PMID:21873635
MGI:MGI:1931079 (MGI:MGI:60925|PMID:8388780)
(PMID:17943189)
RGD PMID:8388780, PMID:17943189, PMID:11072095, PMID:21873635 MGI:MGI:60925, RGD:1300463, RGD:13792537 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rxra retinoid X receptor alpha ISO
IBA
IEA
(PMID:17538076)
PMID:21873635
(MGI:MGI:50850|PMID:1312497), (MGI:MGI:5538466|PMID:23775127)
GO_REF:0000107
RGD
Ensembl
PMID:1312497, PMID:17538076, PMID:23775127, PMID:21873635 GO_REF:0000107, MGI:MGI:50850, MGI:MGI:5538466, RGD:13792537 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta ISO
IBA
(MGI:MGI:50850|PMID:1312497)
PMID:21873635
RGD PMID:1312497, PMID:21873635 MGI:MGI:50850, RGD:13792537 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Rxrg retinoid X receptor gamma ISO
IBA
IEA
(MGI:MGI:50850|PMID:1312497)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:1312497, PMID:21873635 GO_REF:0000107, MGI:MGI:50850, RGD:13792537 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:19934264) RGD PMID:19934264 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
G Tbx1 T-box transcription factor 1 ISO
ISS
(MGI:MGI:3809313|PMID:18816858)
GO_REF:0000024
RGD
UniProt
PMID:18816858 GO_REF:0000024, MGI:MGI:3809313 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
negative regulation of retinoic acid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calr calreticulin ISO (PMID:8107809) RGD PMID:8107809 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 ISO (PMID:16778766) RGD PMID:16778766 NCBI chr19:9,668,186...9,761,605
Ensembl chr19:9,668,186...9,761,605
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 ISO MGI:MGI:3039046 (MGI:MGI:5466369|PMID:22366455) RGD PMID:22366455 MGI:MGI:5466369 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 ISO MGI:MGI:5007106 (MGI:MGI:5528782|PMID:24005908) RGD PMID:24005908 MGI:MGI:5528782 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (PMID:16179254) RGD PMID:16179254 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO (PMID:16179254) RGD PMID:16179254 NCBI chr  X:106,082,984...106,091,256
Ensembl chr  X:106,083,203...106,085,878
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 ISO MGI:MGI:3617788 (MGI:MGI:3615867|PMID:16428452) RGD PMID:16428452 MGI:MGI:3615867 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Zfp536 zinc finger protein 536 ISO (MGI:MGI:3849343|PMID:19398580) RGD PMID:19398580 MGI:MGI:3849343 NCBI chr 1:93,689,114...94,155,457
Ensembl chr 1:93,851,454...93,949,187
JBrowse link
positive regulation of retinoic acid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl1 ASXL transcriptional regulator 1 ISO
IEA
(MGI:MGI:3688807|PMID:16606617)
GO_REF:0000107
RGD
Ensembl
PMID:16606617 GO_REF:0000107, MGI:MGI:3688807 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
JBrowse link
G Ctbp2 C-terminal binding protein 2 ISO (MGI:MGI:5538466|PMID:23775127)
(PMID:23775127)
RGD PMID:23775127 MGI:MGI:5538466 NCBI chr 1:205,001,354...205,030,565
Ensembl chr 1:205,001,396...205,040,755
JBrowse link
G Klf2 Kruppel-like factor 2 ISO (PMID:26416422) RGD PMID:26416422 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Nr2c1 nuclear receptor subfamily 2, group C, member 1 ISO (MGI:MGI:5285179|PMID:16130175) RGD PMID:16130175 MGI:MGI:5285179 NCBI chr 7:35,069,807...35,122,810
Ensembl chr 7:35,069,814...35,122,796
JBrowse link
G Trim16 tripartite motif-containing 16 ISO (PMID:16636064) RGD PMID:16636064 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
regulation of retinoic acid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 ISO MGI:MGI:3764691 (MGI:MGI:5547469|PMID:23991089) RGD PMID:23991089 MGI:MGI:5547469 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Snw1 SNW domain containing 1 ISO (PMID:14985122) RGD PMID:14985122 NCBI chr 6:111,483,698...111,507,782
Ensembl chr 6:111,483,703...111,507,782
JBrowse link
retinoic acid receptor signaling pathway involved in somitogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 ISO MGI:MGI:1100864|MGI:MGI:1857891 (MGI:MGI:3578715|PMID:15889094) RGD PMID:15889094 MGI:MGI:3578715 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    signaling 7588
      signal transduction 7015
        intracellular receptor signaling pathway 255
          retinoic acid receptor signaling pathway 34
            negative regulation of retinoic acid receptor signaling pathway 8
            positive regulation of retinoic acid receptor signaling pathway 5
            regulation of retinoic acid receptor signaling pathway + 16
            retinoic acid receptor signaling pathway involved in lung bud formation 0
            retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation 0
            retinoic acid receptor signaling pathway involved in pronephric field specification 0
            retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification 0
            retinoic acid receptor signaling pathway involved in somitogenesis 1
            retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation 0
            retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological process 13071
        regulation of cellular process 12560
          signal transduction 7015
            intracellular receptor signaling pathway 255
              retinoic acid receptor signaling pathway 34
                negative regulation of retinoic acid receptor signaling pathway 8
                positive regulation of retinoic acid receptor signaling pathway 5
                regulation of retinoic acid receptor signaling pathway + 16
                retinoic acid receptor signaling pathway involved in lung bud formation 0
                retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation 0
                retinoic acid receptor signaling pathway involved in pronephric field specification 0
                retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification 0
                retinoic acid receptor signaling pathway involved in somitogenesis 1
                retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation 0
                retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.