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ONTOLOGY REPORT - ANNOTATIONS


Term:enteric nervous system development
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Accession:GO:0048484 term browser browse the term
Definition:The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.


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enteric nervous system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1600115
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1581884
RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1600115
RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Kif26a kinesin family member 26A JBrowse link 6 136,720,254 136,755,515 RGD:1624291
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:1624291
G Phactr4 phosphatase and actin regulator 4 JBrowse link 5 150,533,895 150,609,423 RGD:1624291
G Phox2a paired-like homeobox 2a JBrowse link 1 166,893,734 166,898,252 RGD:13792537
G Phox2b paired-like homeobox 2b JBrowse link 14 42,711,169 42,718,707 RGD:1624291
RGD:13792537
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
G Sox10 SRY-box transcription factor 10 JBrowse link 7 120,393,238 120,403,523 RGD:1624291
RGD:13792537
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:1624291
RGD:13792537
RGD:1600115
G Tlx2 T-cell leukemia homeobox 2 JBrowse link 4 114,766,401 114,768,243 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    multicellular organismal process 8910
      multicellular organism development 5621
        system development 5156
          enteric nervous system development 13
Path 2
Term Annotations click to browse term
  biological_process 19576
    developmental process 6694
      anatomical structure development 6153
        multicellular organism development 5621
          system development 5156
            nervous system development 2640
              autonomic nervous system development 49
                enteric nervous system development 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.