ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of biological process
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Accession:GO:0048519 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
Synonyms:exact_synonym: down regulation of biological process;   downregulation of biological process;   negative regulation of physiological process
 narrow_synonym: inhibition of biological process
 alt_id: GO:0043118


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Path 1
Term Annotations click to browse term
  biological_process 17896
    negative regulation of biological process 5354
      negative regulation of 3'-UTR-mediated mRNA stabilization 0
      negative regulation of DNA-binding transcription factor activity + 165
      negative regulation of GTPase activity 38
      negative regulation of action potential + 10
      negative regulation of asexual reproduction + 0
      negative regulation of behavior + 25
      negative regulation of cell killing + 30
      negative regulation of cellular process + 4779
      negative regulation of cellular protein localization + 121
      negative regulation of circadian rhythm + 19
      negative regulation of cohesin unloading 0
      negative regulation of developmental pigmentation + 1
      negative regulation of developmental process + 1079
      negative regulation of dosage compensation by inactivation of X chromosome 0
      negative regulation of establishment of RNA localization to telomere 1
      negative regulation of establishment of protein localization + 211
      negative regulation of fibrinolysis 8
      negative regulation of growth + 289
      negative regulation of guanyl-nucleotide exchange factor activity + 8
      negative regulation of hemostasis + 50
      negative regulation of immune system process + 483
      negative regulation of interphase mitotic telomere clustering 0
      negative regulation of intracellular mRNA localization + 0
      negative regulation of lipid localization + 45
      negative regulation of locomotion + 347
      negative regulation of long-term synaptic depression 3
      negative regulation of long-term synaptic potentiation 12
      negative regulation of maintenance of permeability of blood-brain barrier 1
      negative regulation of membrane depolarization + 6
      negative regulation of membrane hyperpolarization 1
      negative regulation of metabolic process + 2908
      negative regulation of mitotic telomere tethering at nuclear periphery 0
      negative regulation of multi-organism process + 242
      negative regulation of multicellular organismal process + 1349
      negative regulation of nitrogen utilization + 0
      negative regulation of nuclear receptor transcription coactivator activity 1
      negative regulation of phosphorus utilization 0
      negative regulation of proteasome-activating ATPase activity 0
      negative regulation of protein localization to cell-cell adherens junction 0
      negative regulation of protein localization to presynapse 0
      negative regulation of receptor localization to synapse 1
      negative regulation of reproductive process + 73
      negative regulation of response to stimulus + 1597
      negative regulation of ribonucleoprotein complex localization + 0
      negative regulation of short-term synaptic potentiation 1
      negative regulation of signaling + 1322
      negative regulation of sulfur utilization 0
      negative regulation of telomerase RNA localization to Cajal body 0
      negative regulation of transport + 566
Path 2
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological process 11951
        negative regulation of biological process 5354
          negative regulation of 3'-UTR-mediated mRNA stabilization 0
          negative regulation of DNA-binding transcription factor activity + 165
          negative regulation of GTPase activity 38
          negative regulation of action potential + 10
          negative regulation of asexual reproduction + 0
          negative regulation of behavior + 25
          negative regulation of cell killing + 30
          negative regulation of cellular process + 4779
          negative regulation of cellular protein localization + 121
          negative regulation of circadian rhythm + 19
          negative regulation of cohesin unloading 0
          negative regulation of developmental pigmentation + 1
          negative regulation of developmental process + 1079
          negative regulation of dosage compensation by inactivation of X chromosome 0
          negative regulation of establishment of RNA localization to telomere 1
          negative regulation of establishment of protein localization + 211
          negative regulation of fibrinolysis 8
          negative regulation of growth + 289
          negative regulation of guanyl-nucleotide exchange factor activity + 8
          negative regulation of hemostasis + 50
          negative regulation of immune system process + 483
          negative regulation of interphase mitotic telomere clustering 0
          negative regulation of intracellular mRNA localization + 0
          negative regulation of lipid localization + 45
          negative regulation of locomotion + 347
          negative regulation of long-term synaptic depression 3
          negative regulation of long-term synaptic potentiation 12
          negative regulation of maintenance of permeability of blood-brain barrier 1
          negative regulation of membrane depolarization + 6
          negative regulation of membrane hyperpolarization 1
          negative regulation of metabolic process + 2908
          negative regulation of mitotic telomere tethering at nuclear periphery 0
          negative regulation of multi-organism process + 242
          negative regulation of multicellular organismal process + 1349
          negative regulation of nitrogen utilization + 0
          negative regulation of nuclear receptor transcription coactivator activity 1
          negative regulation of phosphorus utilization 0
          negative regulation of proteasome-activating ATPase activity 0
          negative regulation of protein localization to cell-cell adherens junction 0
          negative regulation of protein localization to presynapse 0
          negative regulation of receptor localization to synapse 1
          negative regulation of reproductive process + 73
          negative regulation of response to stimulus + 1597
          negative regulation of ribonucleoprotein complex localization + 0
          negative regulation of short-term synaptic potentiation 1
          negative regulation of signaling + 1322
          negative regulation of sulfur utilization 0
          negative regulation of telomerase RNA localization to Cajal body 0
          negative regulation of transport + 566
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.