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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of muscle organ development
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Accession:GO:0048635 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
Synonyms:exact_synonym: down regulation of muscle development;   downregulation of muscle development
 narrow_synonym: inhibition of muscle development


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negative regulation of muscle organ development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 IDA RGD PMID:19057004 RGD:2306938 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Sfmbt1 Scm-like with four mbt domains 1 ISO
ISS
(PMID:23349461)
GO_REF:0000024
RGD
UniProt
PMID:23349461 GO_REF:0000024 NCBI chr16:6,775,648...6,896,155
Ensembl chr16:6,779,281...6,895,299
JBrowse link
negative regulation of cardiac muscle tissue development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf3 fibroblast growth factor 3 ISO (PMID:20702560) RGD PMID:20702560 NCBI chr 1:218,003,018...218,006,942
Ensembl chr 1:218,003,018...218,006,942
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO (PMID:20702560) RGD PMID:20702560 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
negative regulation of skeletal muscle tissue development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nras NRAS proto-oncogene, GTPase ISO MGI:MGI:2676890 (MGI:MGI:4839883|PMID:20534588) RGD PMID:20534588 MGI:MGI:4839883 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
(PMID:9770491)
GO_REF:0000024
RGD
UniProt
PMID:9770491 GO_REF:0000024 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 ISO (MGI:MGI:4838954|PMID:20124407) RGD PMID:20124407 MGI:MGI:4838954 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:69156|PMID:7958419), (MGI:MGI:76047|PMID:7664846) RGD PMID:7664846, PMID:7958419 MGI:MGI:69156, MGI:MGI:76047 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Usp19 ubiquitin specific peptidase 19 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5315325|PMID:21971047)
Ensembl
UniProt
RGD
PMID:21971047 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5315325 NCBI chr 8:117,280,690...117,291,729
Ensembl chr 8:117,280,705...117,291,351
JBrowse link
G Usp2 ubiquitin specific peptidase 2 IDA PMID:10938131 UniProt PMID:10938131 RGD:634247 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Ybx3 Y box binding protein 3 ISO
IEA
(MGI:MGI:3808638|PMID:18676817)
GO_REF:0000107
RGD
Ensembl
PMID:18676817 GO_REF:0000107, MGI:MGI:3808638 NCBI chr 4:165,606,819...165,630,041
Ensembl chr 4:165,606,819...165,630,118
JBrowse link
negative regulation of striated muscle tissue development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IMP RGD PMID:16723531 RGD:1580249 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO
IEA
(PMID:14749725)
GO_REF:0000107
RGD
Ensembl
PMID:14749725 GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Hdac7 histone deacetylase 7 TAS PMID:12711221 UniProt PMID:12711221 RGD:8553516 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 ISO
IEA
(MGI:MGI:3656361|PMID:16936075)
GO_REF:0000107
RGD
Ensembl
PMID:16936075 GO_REF:0000107, MGI:MGI:3656361 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Luc7l LUC7-like ISO (MGI:MGI:3055693|PMID:15474286) RGD PMID:15474286 MGI:MGI:3055693 NCBI chr10:15,538,878...15,572,651
Ensembl chr10:15,538,872...15,568,638
JBrowse link
G Sirt2 sirtuin 2 IEA
ISO
GO_REF:0000107
(PMID:12887892)
Ensembl
RGD
PMID:12887892 GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
G Sox15 SRY-box transcription factor 15 ISO (MGI:MGI:1858709|PMID:10821863) RGD PMID:10821863 MGI:MGI:1858709 NCBI chr10:56,260,514...56,263,503
Ensembl chr10:56,260,514...56,263,503
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:1201268|PMID:9520323) RGD PMID:9520323 MGI:MGI:1201268 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of multicellular organismal process 1123
        negative regulation of muscle organ development 18
          negative regulation of somitomeric trunk muscle development 0
          negative regulation of striated muscle tissue development + 16
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              muscle organ development 350
                regulation of muscle organ development 54
                  negative regulation of muscle organ development 18
                    negative regulation of somitomeric trunk muscle development 0
                    negative regulation of striated muscle tissue development + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.