ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of smooth muscle cell proliferation
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Accession:GO:0048661 term browser browse the term
Definition:Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
Synonyms:exact_synonym: positive regulation of SMC proliferation;   up regulation of smooth muscle cell proliferation;   upregulation of smooth muscle cell proliferation
 narrow_synonym: activation of smooth muscle cell proliferation;   stimulation of smooth muscle cell proliferation


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positive regulation of smooth muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:2301071
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1625344
RGD:7244285
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313013
RGD:1624291
RGD:1600115
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:1626091
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:1600115
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:5509792
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G C3ar1 complement C3a receptor 1 JBrowse link 4 155,681,767 155,691,240 RGD:7411627
G Calcrl calcitonin receptor like receptor JBrowse link 3 71,747,938 71,845,487 RGD:1624291
RGD:1600115
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Ccn4 cellular communication network factor 4 JBrowse link 7 107,695,227 107,723,759 RGD:10003107
G Cdh13 cadherin 13 JBrowse link 19 50,848,793 51,971,618 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:4891893
RGD:13673777
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:8693734
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1581908
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:10395311
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:2316285
RGD:632743
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:8655666
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:2289848
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1582498
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1598489
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:10045551
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 29,330,302 29,340,185 RGD:1624291
RGD:1600115
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:9681442
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1626319
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508694
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1624291
RGD:1600115
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046007
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145470
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655954
RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:1579817
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:1579817
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:2307394
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:4892625
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:2290591
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1624291
G Mnat1 MNAT1 component of CDK activating kinase JBrowse link 6 95,995,341 96,153,331 RGD:2308868
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10003166
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532682
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:10059612
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1579817
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:2311234
G Notch3 notch receptor 3 JBrowse link 7 14,138,495 14,189,688 RGD:1600115
RGD:1624291
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:633401
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:1625500
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
G Orc1 origin recognition complex, subunit 1 JBrowse link 5 128,186,651 128,212,901 RGD:9588277
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:7327157
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:2292197
RGD:1624291
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:9854640
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:13207417
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:7242177
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:2292473
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10043166
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1642591
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:2292605
G Rab5a RAB5A, member RAS oncogene family JBrowse link 9 5,910 6,065 RGD:4892313
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:2306423
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:7207234
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1643021
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:1581747
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:1304398
G Skp2 S-phase kinase associated protein 2 JBrowse link 2 58,506,146 58,534,211 RGD:2315048
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:1600088
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:1601384
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1600115
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1601605
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:1579990
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1579817
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1580560
G Zfp143 zinc finger protein 143 JBrowse link 1 174,702,310 174,738,133 RGD:9743924
positive regulation of vascular smooth muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 JBrowse link 11 25,342,119 25,350,938 RGD:1600115
RGD:1624291
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11039416
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:2303063
G Ddx39b DExD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:10401139
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:13601996
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
RGD:1600115
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
RGD:13601993
G Foxj2 forkhead box J2 JBrowse link 4 155,653,446 155,679,815 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:13524616
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13507308
G Gnai3 G protein subunit alpha i3 JBrowse link 2 210,896,779 210,934,733 RGD:13507308
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13513992
RGD:13792711
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11667099
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:1600115
RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:10403075
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1600115
RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1600115
RGD:1624291
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:10412321
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:10412065
G Mef2d myocyte enhancer factor 2D JBrowse link 2 187,511,775 187,541,285 RGD:1600115
RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:1624291
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1600115
RGD:1624291
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1600115
RGD:1624291
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:11073699
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1600115
RGD:1624291
G P2ry6 pyrimidinergic receptor P2Y6 JBrowse link 1 165,972,439 166,008,348 RGD:1600115
RGD:1624291
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:11533949
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:1624291
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11038675
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    cell population proliferation 2071
      positive regulation of cell population proliferation 1018
        positive regulation of smooth muscle cell proliferation 112
          positive regulation of vascular smooth muscle cell proliferation 36
Path 2
Term Annotations click to browse term
  biological_process 17926
    biological regulation 12622
      regulation of biological process 11964
        positive regulation of biological process 6150
          positive regulation of cellular process 5443
            positive regulation of cell population proliferation 1018
              positive regulation of smooth muscle cell proliferation 112
                positive regulation of vascular smooth muscle cell proliferation 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.