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ONTOLOGY REPORT - ANNOTATIONS


Term:neuron fate commitment
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Accession:GO:0048663 term browser browse the term
Definition:The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
Synonyms:exact_synonym: neuron lineage restriction;   neuronal lineage restriction
 alt_id: GO:0042055


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neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1600115
RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Epop elongin BC and polycomb repressive complex 2 associated protein JBrowse link 10 85,573,369 85,574,889 RGD:1624291
RGD:13792537
G Foxn4 forkhead box N4 JBrowse link 12 48,101,012 48,121,281 RGD:1624291
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
G Gbx1 gastrulation brain homeobox 1 JBrowse link 4 7,173,961 7,200,752 RGD:1624291
RGD:1600115
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Gsx1 GS homeobox 1 JBrowse link 12 9,605,873 9,607,168 RGD:1624291
RGD:1600115
G Gsx2 GS homeobox 2 JBrowse link 14 35,650,985 35,652,709 RGD:1624291
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G Isl2 ISL LIM homeobox 2 JBrowse link 8 60,117,565 60,122,716 RGD:1624291
G Lbx1 ladybird homeobox 1 JBrowse link 1 264,973,315 264,975,132 RGD:1624291
G Myt1l myelin transcription factor 1-like JBrowse link 6 48,452,385 48,843,443 RGD:1600115
RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Notch3 notch receptor 3 JBrowse link 7 14,138,495 14,189,688 RGD:1624291
RGD:1600115
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
RGD:1600115
G Olig1 oligodendrocyte transcription factor 1 JBrowse link 11 31,428,377 31,430,519 RGD:1624291
RGD:1600115
G Olig2 oligodendrocyte transcription factor 2 JBrowse link 11 31,389,514 31,392,890 RGD:1624291
RGD:1600115
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
G Pax7 paired box 7 JBrowse link 5 158,211,001 158,313,510 RGD:1624291
RGD:1600115
G Pou3f2 POU class 3 homeobox 2 JBrowse link 5 36,677,452 36,683,356 RGD:1624291
RGD:1600115
G Ptf1a pancreas associated transcription factor 1a JBrowse link 17 86,199,623 86,201,477 RGD:1624291
RGD:1600115
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:1624291
G Zfp521 zinc finger protein 521 JBrowse link 18 5,022,042 5,315,242 RGD:1624291
RGD:1600115
auditory receptor cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:8553270
G Jag2 jagged canonical Notch ligand 2 JBrowse link 6 137,711,144 137,733,331 RGD:1600115
RGD:8553713
RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
auditory receptor cell fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
RGD:1600115
auditory receptor cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
RGD:1600115
camera-type eye photoreceptor cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
RGD:1600115
cerebral cortex GABAergic interneuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlx1 distal-less homeobox 1 JBrowse link 3 58,164,931 58,169,521 RGD:1624291
RGD:1600115
G Dlx2 distal-less homeobox 2 JBrowse link 3 58,180,088 58,181,971 RGD:1624291
RGD:1600115
commitment of neuronal cell to specific neuron type in forebrain term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
RGD:1600115
G Fezf2 Fez family zinc finger 2 JBrowse link 15 12,825,333 12,831,496 RGD:1624291
RGD:1600115
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Satb2 SATB homeobox 2 JBrowse link 9 63,456,877 63,642,193 RGD:1624291
RGD:1600115
G Tbr1 T-box brain transcription factor 1 JBrowse link 3 47,677,720 47,685,902 RGD:1624291
RGD:13792537
eye photoreceptor cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
forebrain neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhx6 LIM homeobox 6 JBrowse link 3 15,409,349 15,433,504 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
negative regulation of retinal cone cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casz1 castor zinc finger 1 JBrowse link 5 165,625,119 165,777,053 RGD:1624291
neuron fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:1624291
RGD:1600115
G Fezf2 Fez family zinc finger 2 JBrowse link 15 12,825,333 12,831,496 RGD:1624291
RGD:1600115
G Foxg1 forkhead box G1 JBrowse link 6 69,971,227 69,974,037 RGD:1624291
RGD:1600115
G Lbx1 ladybird homeobox 1 JBrowse link 1 264,973,315 264,975,132 RGD:1624291
RGD:1600115
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:1624291
G Prrx1 paired related homeobox 1 JBrowse link 13 81,147,038 81,215,559 RGD:1624291
RGD:1600115
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:1624291
RGD:1600115
neuron fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1600115
RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Dmrta2 DMRT-like family A2 JBrowse link 5 129,754,295 129,760,045 RGD:1624291
G Ehmt2 euchromatic histone lysine methyltransferase 2 JBrowse link 20 4,576,033 4,592,980 RGD:1624291
RGD:1600115
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
RGD:1600115
G Fev FEV transcription factor, ETS family member JBrowse link 9 82,142,981 82,146,855 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Gsx2 GS homeobox 2 JBrowse link 14 35,650,985 35,652,709 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:13792537
G Isl2 ISL LIM homeobox 2 JBrowse link 8 60,117,565 60,122,716 RGD:13792537
G Myt1l myelin transcription factor 1-like JBrowse link 6 48,452,385 48,843,443 RGD:1600115
RGD:1624291
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:2325628
G Pou3f2 POU class 3 homeobox 2 JBrowse link 5 36,677,452 36,683,356 RGD:1600115
RGD:1624291
G Pou4f1 POU class 4 homeobox 1 JBrowse link 15 88,618,255 88,622,712 RGD:1624291
RGD:1600115
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
RGD:1600115
G Tlx3 T-cell leukemia, homeobox 3 JBrowse link 10 18,128,869 18,131,745 RGD:1624291
RGD:1600115
noradrenergic neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esrp1 epithelial splicing regulatory protein 1 JBrowse link 5 24,576,988 24,631,758 RGD:1600115
RGD:1624291
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlx1 distal-less homeobox 1 JBrowse link 3 58,164,931 58,169,521 RGD:1624291
RGD:1600115
G Dlx2 distal-less homeobox 2 JBrowse link 3 58,180,088 58,181,971 RGD:1624291
RGD:1600115
G Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 JBrowse link 7 2,875,898 2,905,463 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lbx1 ladybird homeobox 1 JBrowse link 1 264,973,315 264,975,132 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
RGD:1600115
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Evx1 even-skipped homeobox 1 JBrowse link 4 82,370,829 82,374,313 RGD:1624291
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
RGD:1600115
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
retinal rod cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casz1 castor zinc finger 1 JBrowse link 5 165,625,119 165,777,053 RGD:1624291
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115
spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoxc10 homeo box C10 JBrowse link 7 144,577,578 144,582,802 RGD:1624291
RGD:1600115
G Hoxd10 homeo box D10 JBrowse link 3 61,614,133 61,617,342 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
G Isl2 ISL LIM homeobox 2 JBrowse link 8 60,117,565 60,122,716 RGD:1624291
RGD:1600115
G Lhx3 LIM homeobox 3 JBrowse link 3 3,653,861 3,662,509 RGD:1624291
RGD:1600115
G Mnx1 motor neuron and pancreas homeobox 1 JBrowse link 4 2,376,350 2,381,308 RGD:1624291
RGD:13792537
G Olig3 oligodendrocyte transcription factor 3 JBrowse link 1 14,797,766 14,799,835 RGD:1624291
RGD:1600115
subpallium neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Gsx2 GS homeobox 2 JBrowse link 14 35,650,985 35,652,709 RGD:1624291
RGD:1600115
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Dll4 delta like canonical Notch ligand 4 JBrowse link 3 111,135,011 111,146,746 RGD:1624291
RGD:1600115
G Foxn4 forkhead box N4 JBrowse link 12 48,101,012 48,121,281 RGD:1624291
RGD:1600115
ventral spinal cord interneuron fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbx1 developing brain homeobox 1 JBrowse link 1 104,969,218 104,973,648 RGD:1624291
RGD:1600115
G Dmrt3 doublesex and mab-3 related transcription factor 3 JBrowse link 1 243,589,607 243,602,926 RGD:1624291
RGD:1600115
G Lhx3 LIM homeobox 3 JBrowse link 3 3,653,861 3,662,509 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:8553789
G Sox1 SRY-box transcription factor 1 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cellular developmental process 4400
        cell fate commitment 282
          neuron fate commitment 78
            cardiac neuron fate commitment 0
            cerebral cortex GABAergic interneuron fate commitment 2
            forebrain neuron fate commitment + 13
            inner ear receptor cell fate commitment + 6
            neuron fate determination + 9
            neuron fate specification + 37
            noradrenergic neuron fate commitment + 1
            olfactory bulb interneuron fate commitment 0
            photoreceptor cell fate commitment + 3
            somatic motor neuron fate commitment + 1
            subpallium neuron fate commitment 2
            ventral spinal cord interneuron fate commitment + 16
Path 2
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        multicellular organism development 5534
          system development 5081
            nervous system development 2592
              neurogenesis 1876
                generation of neurons 1741
                  neuron differentiation 1567
                    neuron fate commitment 78
                      cardiac neuron fate commitment 0
                      cerebral cortex GABAergic interneuron fate commitment 2
                      forebrain neuron fate commitment + 13
                      inner ear receptor cell fate commitment + 6
                      neuron fate determination + 9
                      neuron fate specification + 37
                      noradrenergic neuron fate commitment + 1
                      olfactory bulb interneuron fate commitment 0
                      photoreceptor cell fate commitment + 3
                      somatic motor neuron fate commitment + 1
                      subpallium neuron fate commitment 2
                      ventral spinal cord interneuron fate commitment + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.