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ONTOLOGY REPORT - ANNOTATIONS


Term:response to axon injury
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Accession:GO:0048678 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.


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response to axon injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313010
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:2311210
G Arf4 ADP-ribosylation factor 4 JBrowse link 16 2,338,333 2,354,909 RGD:2316175
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4143237
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:4143237
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:14398458
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:2316482
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:2306507
RGD:2306510
RGD:2306509
RGD:2306508
G Cyss cystatin S JBrowse link 3 144,427,430 144,431,768 RGD:2306751
RGD:2306752
G Dpysl3 dihydropyrimidinase-like 3 JBrowse link 18 37,716,371 37,819,347 RGD:1600115
RGD:8554592
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:2311554
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1601067
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1582139
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Flrt3 fibronectin leucine rich transmembrane protein 3 JBrowse link 3 134,684,446 134,696,586 RGD:1579783
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:2312528
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312528
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:7771530
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link 13 107,690,111 107,886,476 RGD:9831168
G Lgals1 galectin 1 JBrowse link 7 120,153,184 120,156,290 RGD:2316527
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:2316612
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:2303707
G Map1b microtubule-associated protein 1B JBrowse link 2 29,675,391 29,768,750 RGD:2304007
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:2293210
G Matn2 matrilin 2 JBrowse link 7 72,985,832 73,210,093 RGD:1624291
G Matn4 matrilin 4 JBrowse link 3 160,838,632 160,853,650 RGD:1624291
G Max MYC associated factor X JBrowse link 6 99,984,260 100,011,460 RGD:2316820
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12738219
G Morn4 MORN repeat containing 4 JBrowse link 1 261,323,079 261,333,383 RGD:1624291
RGD:1600115
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:10054082
G Musk muscle associated receptor tyrosine kinase JBrowse link 5 75,392,790 75,498,694 RGD:2317114
G Naip6 NLR family, apoptosis inhibitory protein 6 JBrowse link 2 30,377,505 30,418,578 RGD:1299309
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:4143237
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:5684341
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:2325627
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:9743915
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:13673840
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:13673748
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:2308892
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449483
G Rangap1 RAN GTPase activating protein 1 JBrowse link 7 122,939,266 122,967,178 RGD:9835000
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:2317775
G Sarm1 sterile alpha and TIR motif containing 1 JBrowse link 10 65,742,343 65,766,050 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1580344
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317154
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:5133729
G Txn2 thioredoxin 2 JBrowse link 7 119,144,350 119,158,173 RGD:2306158
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:5133729
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
G Uck2 uridine-cytidine kinase 2 JBrowse link 13 85,376,716 85,443,976 RGD:634248
axon extension involved in regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link 8 117,268,335 117,280,517 RGD:1624291
RGD:1600115
axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Chl1 cell adhesion molecule L1-like JBrowse link 4 70,269,414 70,331,313 RGD:1303346
G Cspg5 chondroitin sulfate proteoglycan 5 JBrowse link 8 118,333,695 118,348,040 RGD:1298825
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:632464
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:11537480
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:10054082
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:13792537
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:2311122
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641846
G Jam3 junctional adhesion molecule 3 JBrowse link 8 28,147,110 28,208,466 RGD:7488944
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1624291
G LOC100912195 protein BEX1-like JBrowse link 1 116,565,779 116,567,283 RGD:1624291
G Mag myelin-associated glycoprotein JBrowse link 1 89,345,325 89,360,905 RGD:1624291
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 JBrowse link 10 14,259,394 14,299,276 RGD:13673780
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:10054082
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:9698439
G Nefm neurofilament medium JBrowse link 15 44,855,307 44,860,604 RGD:9698447
G Nrep neuronal regeneration related protein JBrowse link 18 26,183,753 26,212,796 RGD:1540387
RGD:13792537
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1643108
G Vcan versican JBrowse link 2 18,490,102 18,587,340 RGD:632591
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RGD1307443 similar to mKIAA0319 protein JBrowse link 17 42,163,245 42,226,725 RGD:1624291
G Tnr tenascin R JBrowse link 13 77,602,249 77,678,385 RGD:1624291
RGD:1600115
negative regulation of axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cers2 ceramide synthase 2 JBrowse link 2 196,487,656 196,495,930 RGD:11041067
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:5688750
RGD:1600115
RGD:1624291
RGD:5688782
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:1624291
G Klk8 kallikrein related-peptidase 8 JBrowse link 1 99,735,168 99,742,011 RGD:1600115
RGD:1624291
G Kremen1 kringle containing transmembrane protein 1 JBrowse link 14 85,441,209 85,503,661 RGD:1600115
RGD:1624291
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 JBrowse link 2 206,928,708 206,997,915 RGD:1624291
G Neo1 neogenin 1 JBrowse link 8 63,649,871 63,756,394 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Ptprs protein tyrosine phosphatase, receptor type, S JBrowse link 9 10,585,360 10,646,205 RGD:1600115
RGD:1624291
G Rgma repulsive guidance molecule BMP co-receptor a JBrowse link 1 134,699,053 134,742,512 RGD:9850138
G Rtn4r reticulon 4 receptor JBrowse link 11 86,992,665 87,017,091 RGD:1624291
RGD:1600115
G Rtn4rl1 reticulon 4 receptor-like 1 JBrowse link 10 62,035,866 62,109,075 RGD:1624291
RGD:1600115
G Xylt1 xylosyltransferase 1 JBrowse link 1 186,939,698 187,264,758 RGD:2313145
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581125
negative regulation of formation of growth cone in injured axon term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1624291
negative regulation of Schwann cell proliferation involved in axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cers2 ceramide synthase 2 JBrowse link 2 196,487,656 196,495,930 RGD:11041067
peripheral nervous system axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:2311210
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:2311210
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:2311210
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:2311210
G Calu calumenin JBrowse link 4 56,625,611 56,653,112 RGD:2316214
G Chst3 carbohydrate sulfotransferase 3 JBrowse link 20 29,731,828 29,768,656 RGD:1600854
G Map1b microtubule-associated protein 1B JBrowse link 2 29,675,391 29,768,750 RGD:2304028
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1582605
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:2326091
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:1624291
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:1624291
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317177
positive regulation of axon extension involved in regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cntf ciliary neurotrophic factor JBrowse link 1 229,599,009 229,601,032 RGD:12793002
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800520
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:1624291
G Ocm oncomodulin JBrowse link 12 12,611,121 12,634,472 RGD:12793002
positive regulation of axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
G Cntf ciliary neurotrophic factor JBrowse link 1 229,599,009 229,601,032 RGD:1626128
RGD:13792537
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:7205517
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046026
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1642004
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:2306515
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:10449012
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:14397577
G Scarf1 scavenger receptor class F, member 1 JBrowse link 10 63,662,967 63,683,916 RGD:1624291
G Stk24 serine/threonine kinase 24 JBrowse link 15 106,629,258 106,678,917 RGD:2317003
positive regulation of collateral sprouting of injured axon term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800520
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1624291
positive regulation of optical nerve axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ocm oncomodulin JBrowse link 12 12,611,121 12,634,472 RGD:12793002
regulation of axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 JBrowse link 2 206,928,708 206,997,915 RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
G Neo1 neogenin 1 JBrowse link 8 63,649,871 63,756,394 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Ptprf protein tyrosine phosphatase, receptor type, F JBrowse link 5 137,036,936 137,112,930 RGD:1624291
RGD:1600115
G Stk24 serine/threonine kinase 24 JBrowse link 15 106,629,258 106,678,917 RGD:1600115
RGD:1624291
regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Omg oligodendrocyte-myelin glycoprotein JBrowse link 10 66,845,654 66,848,388 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 19676
    response to stimulus 10492
      response to stress 4012
        response to wounding 614
          response to axon injury 120
            axon regeneration + 72
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.