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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of axon regeneration
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Accession:GO:0048681 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
Synonyms:exact_synonym: down regulation of axon regeneration;   downregulation of axon regeneration
 narrow_synonym: inhibition of axon regeneration


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negative regulation of axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cers2 ceramide synthase 2 JBrowse link 2 196,487,656 196,495,930 RGD:11041067
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:5688750
RGD:1600115
RGD:1624291
RGD:5688782
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:1624291
RGD:1600115
G Klk8 kallikrein related-peptidase 8 JBrowse link 1 99,735,168 99,742,011 RGD:1600115
RGD:1624291
G Kremen1 kringle containing transmembrane protein 1 JBrowse link 14 85,441,209 85,503,661 RGD:1600115
RGD:1624291
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 JBrowse link 2 206,928,708 206,997,915 RGD:1624291
RGD:1600115
G Neo1 neogenin 1 JBrowse link 8 63,649,871 63,756,394 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Ptprs protein tyrosine phosphatase, receptor type, S JBrowse link 9 10,585,360 10,646,205 RGD:1600115
RGD:1624291
G Rgma repulsive guidance molecule BMP co-receptor a JBrowse link 1 134,699,053 134,742,512 RGD:9850138
G Rtn4r reticulon 4 receptor JBrowse link 11 86,992,665 87,017,091 RGD:1624291
RGD:1600115
G Rtn4rl1 reticulon 4 receptor-like 1 JBrowse link 10 62,035,866 62,109,075 RGD:1624291
RGD:1600115
G Xylt1 xylosyltransferase 1 JBrowse link 1 186,939,698 187,264,758 RGD:2313145
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RGD1307443 similar to mKIAA0319 protein JBrowse link 17 42,163,245 42,226,725 RGD:1624291
G Tnr tenascin R JBrowse link 13 77,602,249 77,678,385 RGD:1624291
RGD:1600115
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581125
negative regulation of formation of growth cone in injured axon term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1624291
negative regulation of Schwann cell proliferation involved in axon regeneration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cers2 ceramide synthase 2 JBrowse link 2 196,487,656 196,495,930 RGD:11041067

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    response to stimulus 9928
      response to external stimulus 2945
        negative regulation of response to external stimulus 383
          negative regulation of axon regeneration 17
            negative regulation of MAPK cascade involved in axon regeneration 0
            negative regulation of Schwann cell proliferation involved in axon regeneration 1
            negative regulation of collateral sprouting of intact axon in response to injury 1
            negative regulation of optical nerve axon regeneration 0
            negative regulation of sprouting of injured axon + 3
Path 2
Term Annotations click to browse term
  biological_process 18166
    developmental process 6539
      anatomical structure development 6020
        multicellular organism development 5501
          system development 5050
            nervous system development 2583
              neurogenesis 1869
                generation of neurons 1735
                  neuron differentiation 1563
                    neuron development 1273
                      neuron projection development 1126
                        neuron projection regeneration 82
                          axon regeneration 71
                            regulation of axon regeneration 37
                              negative regulation of axon regeneration 17
                                negative regulation of MAPK cascade involved in axon regeneration 0
                                negative regulation of Schwann cell proliferation involved in axon regeneration 1
                                negative regulation of collateral sprouting of intact axon in response to injury 1
                                negative regulation of optical nerve axon regeneration 0
                                negative regulation of sprouting of injured axon + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.