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ONTOLOGY REPORT - ANNOTATIONS


Term:muscle fiber development
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Accession:GO:0048747 term browser browse the term
Definition:The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
Synonyms:exact_synonym: muscle fibre development;   myofiber development;   myofibre development


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muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afg3l2 AFG3-like AAA ATPase 2 JBrowse link 18 67,404,764 67,449,192 RGD:2290270
G Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 JBrowse link 9 107,399,733 107,529,346 RGD:2290270
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit JBrowse link 2 52,428,320 52,676,609 RGD:2290270
G Capzb capping protein (actin filament) muscle Z-line, beta JBrowse link 4 139,192,899 139,291,820 RGD:2290270
G Chrnb1 cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) JBrowse link 11 69,784,036 69,795,966 RGD:2290270
G Comp cartilage oligomeric matrix protein JBrowse link 8 70,373,548 70,382,066 RGD:2290270
G Dmd dystrophin, muscular dystrophy JBrowse link X 82,814,664 85,205,050 RGD:2290270
G Dysf dysferlin JBrowse link 6 84,008,361 84,211,060 RGD:2290270
G Flnc filamin C, gamma JBrowse link 6 29,433,153 29,461,889 RGD:2290270
G Lox lysyl oxidase JBrowse link 18 52,516,060 52,529,867 RGD:2290270
G Mir208a microRNA 208a JBrowse link 14 54,949,060 54,949,142 RGD:2290270
G Mir208b microRNA 208b JBrowse link 14 54,975,700 54,975,776 RGD:2290270
G Mir499 microRNA 499 JBrowse link 2 155,622,880 155,622,958 RGD:2290270
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow JBrowse link 5 122,100,925 122,114,536 RGD:2290270
G Myof myoferlin JBrowse link 19 37,899,036 38,043,577 RGD:2290270
G Neb nebulin JBrowse link 2 52,136,640 52,338,798 RGD:2290270
G Nebl nebulette JBrowse link 2 17,342,673 17,734,949 RGD:2290270
G Nrap nebulin-related anchoring protein JBrowse link 19 56,320,037 56,390,062 RGD:2290270
G Pmp22 peripheral myelin protein 22 JBrowse link 11 63,128,982 63,159,547 RGD:2290270
G Ptcd2 pentatricopeptide repeat domain 2 JBrowse link 13 99,319,649 99,344,678 RGD:2290270
G Sgcb sarcoglycan, beta (dystrophin-associated glycoprotein) JBrowse link 5 73,632,749 73,647,737 RGD:2290270
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 JBrowse link 17 81,373,105 81,738,387 RGD:2290270
G Tmtc3 transmembrane and tetratricopeptide repeat containing 3 JBrowse link 10 100,443,902 100,487,365 RGD:2290270
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 JBrowse link 5 66,676,121 66,687,234 RGD:2290270
G Wfikkn1 WAP, FS, Ig, KU, and NTR-containing protein 1 JBrowse link 17 25,877,628 25,880,858 RGD:2290270
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 JBrowse link 11 94,235,951 94,247,793 RGD:2290270
cardiac muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxadr coxsackie virus and adenovirus receptor JBrowse link 16 78,301,226 78,359,785 RGD:2290270
G Myh11 myosin, heavy polypeptide 11, smooth muscle JBrowse link 16 14,194,527 14,292,188 RGD:2290270
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha JBrowse link 14 54,941,921 54,968,017 RGD:2290270
G Myo18b myosin XVIIIb JBrowse link 5 112,688,876 112,896,461 RGD:2290270
G Myom1 myomesin 1 JBrowse link 17 71,003,332 71,126,856 RGD:2290270
G Myom2 myomesin 2 JBrowse link 8 15,057,653 15,133,420 RGD:2290270
G Myom3 myomesin family, member 3 JBrowse link 4 135,758,800 135,815,571 RGD:2290270
G Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) JBrowse link 11 46,971,077 47,989,451 RGD:2290270
G Tcap titin-cap JBrowse link 11 98,383,811 98,384,953 RGD:2290270
G Ttn titin JBrowse link 2 76,703,980 76,982,557 RGD:2290270
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:2290270
G Zmpste24 zinc metallopeptidase, STE24 JBrowse link 4 121,059,237 121,098,249 RGD:2290270
neuromuscular junction development, skeletal muscle fiber term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pmp22 peripheral myelin protein 22 JBrowse link 11 63,128,982 63,159,547 RGD:2290270
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
positive regulation of skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 19 4,861,216 4,877,909 RGD:2290270
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:2290270
G Lmod3 leiomodin 3 (fetal) JBrowse link 6 97,238,530 97,253,217 RGD:2290270
G Myf5 myogenic factor 5 JBrowse link 10 107,482,908 107,486,927 RGD:2290270
G Myf6 myogenic factor 6 JBrowse link 10 107,492,848 107,494,723 RGD:2290270
G Myod1 myogenic differentiation 1 JBrowse link 7 46,376,474 46,379,092 RGD:2290270
G Myog myogenin JBrowse link 1 134,290,004 134,292,548 RGD:2290270
G Shox2 short stature homeobox 2 JBrowse link 3 66,971,723 66,981,771 RGD:2290270
regulation of skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo22 F-box protein 22 JBrowse link 9 55,208,935 55,224,433 RGD:2290270
G Hdac4 histone deacetylase 4 JBrowse link 1 91,928,779 92,195,702 RGD:2290270
G Hdac5 histone deacetylase 5 JBrowse link 11 102,195,747 102,230,172 RGD:2290270
G Hdac9 histone deacetylase 9 JBrowse link 12 34,047,580 34,917,095 RGD:2290270
G Naca nascent polypeptide-associated complex alpha polypeptide JBrowse link 10 128,035,346 128,048,637 RGD:2290270
skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta1 actin, alpha 1, skeletal muscle JBrowse link 8 123,891,758 123,894,775 RGD:2290270
G Bin3 bridging integrator 3 JBrowse link 14 70,100,089 70,137,964 RGD:2290270
G Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit JBrowse link 1 136,052,806 136,119,822 RGD:2290270
G Cav2 caveolin 2 JBrowse link 6 17,281,185 17,289,130 RGD:2290270
G Dner delta/notch-like EGF repeat containing JBrowse link 1 84,369,839 84,696,221 RGD:2290270
G Gpx1 glutathione peroxidase 1 JBrowse link 9 108,339,080 108,340,342 RGD:2290270
G Homer1 homer scaffolding protein 1 JBrowse link 13 93,303,757 93,405,129 RGD:2290270
G Hottip Hoxa distal transcript antisense RNA JBrowse link 6 52,262,775 52,267,603 RGD:2290270
G Kel Kell blood group JBrowse link 6 41,686,329 41,704,334 RGD:2290270
G Klhl40 kelch-like 40 JBrowse link 9 121,777,499 121,791,200 RGD:2290270
G Klhl41 kelch-like 41 JBrowse link 2 69,670,120 69,684,239 RGD:2290270
G Lmod3 leiomodin 3 (fetal) JBrowse link 6 97,238,530 97,253,217 RGD:2290270
G Myhas myosin heavy chain gene antisense RNA JBrowse link 11 67,224,196 67,237,281 RGD:2290270
G Myod1 myogenic differentiation 1 JBrowse link 7 46,376,474 46,379,092 RGD:2290270
G Myog myogenin JBrowse link 1 134,290,004 134,292,548 RGD:2290270
G Myoparr myogenin promoter-associated myogenic regulatory antisense lncRNA JBrowse link 1 134,288,595 134,289,761 RGD:2290270
G Myorg myogenesis regulating glycosidase (putative) JBrowse link 4 41,491,847 41,503,135 RGD:2290270
G Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 JBrowse link 8 106,058,818 106,130,537 RGD:2290270
G P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 JBrowse link 5 110,339,812 110,343,320 RGD:2290270
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform JBrowse link 3 136,669,714 136,937,727 RGD:2290270
G Rcan1 regulator of calcineurin 1 JBrowse link 16 92,391,951 92,466,169 RGD:2290270
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 13 24,501,524 24,733,806 RGD:2290270
G Ryr1 ryanodine receptor 1, skeletal muscle JBrowse link 7 29,003,340 29,125,179 RGD:2290270
G Selenon selenoprotein N JBrowse link 4 134,537,892 134,552,166 RGD:2290270
G Six1 sine oculis-related homeobox 1 JBrowse link 12 73,041,827 73,046,712 RGD:2290270
G Ski ski sarcoma viral oncogene homolog (avian) JBrowse link 4 155,154,075 155,222,535 RGD:2290270
G Smo smoothened, frizzled class receptor JBrowse link 6 29,735,497 29,761,366 RGD:2290270
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 10 127,501,617 127,508,823 RGD:2290270
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 15 98,770,712 98,778,206 RGD:2290270
G Xk X-linked Kx blood group JBrowse link X 9,272,784 9,313,245 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23017
    cellular process 15767
      cellular developmental process 4446
        cell development 2415
          muscle cell development 205
            striated muscle cell development 191
              muscle fiber development 79
                cardiac muscle fiber development + 13
                skeletal muscle fiber development + 41
Path 2
Term Annotations click to browse term
  biological_process 23017
    cellular process 15767
      cellular developmental process 4446
        cell differentiation 4220
          muscle cell differentiation 394
            striated muscle cell differentiation 315
              striated muscle cell development 191
                muscle fiber development 79
                  cardiac muscle fiber development + 13
                  skeletal muscle fiber development + 41
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.