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ONTOLOGY REPORT - ANNOTATIONS


Term:muscle fiber development
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Accession:GO:0048747 term browser browse the term
Definition:The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
Synonyms:exact_synonym: muscle fibre development;   myofiber development;   myofibre development


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muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 63,141,418 63,185,510 RGD:1624291
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 JBrowse link 8 116,154,661 116,285,643 RGD:1624291
RGD:1600115
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:1624291
G Capzb capping actin protein of muscle Z-line subunit beta JBrowse link 5 157,642,742 157,742,487 RGD:1624291
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit JBrowse link 10 56,390,671 56,403,255 RGD:1624291
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
G Flnc filamin C JBrowse link 4 56,710,934 56,738,779 RGD:1624291
G Lox lysyl oxidase JBrowse link 18 47,500,320 47,577,819 RGD:1624291
G Mir208a microRNA 208a JBrowse link 15 33,613,451 33,613,533 RGD:1624291
G Mir208b microRNA 208b JBrowse link 15 33,639,510 33,639,621 RGD:1624291
G Mir499a microRNA 499a JBrowse link 3 151,138,862 151,138,926 RGD:1624291
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:1624291
RGD:1600115
G Myof myoferlin JBrowse link 1 256,585,410 256,734,727 RGD:1624291
G Neb nebulin JBrowse link 3 37,658,081 37,855,843 RGD:13792537
G Nebl nebulette JBrowse link 17 84,141,014 84,247,038 RGD:13792537
G Nrap nebulin-related anchoring protein JBrowse link 1 277,104,519 277,181,397 RGD:13792537
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Ptcd2 pentatricopeptide repeat domain 2 JBrowse link 2 29,570,581 29,598,328 RGD:1624291
G Sgcb sarcoglycan, beta JBrowse link 14 37,113,194 37,128,623 RGD:1624291
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:1624291
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 JBrowse link 7 40,171,957 40,217,056 RGD:1624291
G Uchl1 ubiquitin C-terminal hydrolase L1 JBrowse link 14 43,133,224 43,143,942 RGD:1624291
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 JBrowse link 10 15,243,429 15,245,757 RGD:1624291
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 JBrowse link 10 81,936,156 81,943,142 RGD:1624291
cardiac muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxadr CXADR, Ig-like cell adhesion molecule JBrowse link 11 16,826,269 16,873,564 RGD:1624291
RGD:1600115
G Myh11 myosin heavy chain 11 JBrowse link 10 764,421 859,184 RGD:1600115
RGD:1624291
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:1600115
RGD:1624291
G Myo18b myosin XVIIIb JBrowse link 12 49,761,100 49,979,745 RGD:1624291
G Myom1 myomesin 1 JBrowse link 9 119,353,840 119,469,196 RGD:13792537
G Myom2 myomesin 2 JBrowse link 16 79,587,136 79,672,871 RGD:13792537
G Myom3 myomesin 3 JBrowse link 5 154,109,293 154,159,943 RGD:13792537
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:1624291
G Tcap titin-cap JBrowse link 10 86,337,705 86,338,414 RGD:1624291
RGD:13792537
G Ttn titin JBrowse link 3 63,565,160 63,837,815 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
neuromuscular junction development, skeletal muscle fiber term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
positive regulation of skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Lmod3 leiomodin 3 JBrowse link 4 129,604,378 129,619,136 RGD:1624291
G Myf5 myogenic factor 5 JBrowse link 7 49,729,533 49,732,974 RGD:13792537
G Myf6 myogenic factor 6 JBrowse link 7 49,739,643 49,741,490 RGD:13792537
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:13792537
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:1624291
RGD:13792537
RGD:1600115
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
regulation of skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo22 F-box protein 22 JBrowse link 8 59,770,032 59,786,061 RGD:1624291
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:1624291
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
G Naca nascent polypeptide associated complex subunit alpha JBrowse link 7 2,458,283 2,470,674 RGD:1624291
skeletal muscle fiber development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta1 actin, alpha 1, skeletal muscle JBrowse link 19 56,674,072 56,677,084 RGD:1624291
RGD:1600115
G Actn1 actinin, alpha 1 JBrowse link 6 103,376,557 103,470,497 RGD:1600115
G Bin3 bridging integrator 3 JBrowse link 15 51,799,339 51,818,697 RGD:1624291
G Cacna1s calcium voltage-gated channel subunit alpha1 S JBrowse link 13 52,889,570 52,964,558 RGD:1624291
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:1624291
RGD:1600115
G Dner delta/notch-like EGF repeat containing JBrowse link 9 91,965,866 92,291,172 RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:1624291
RGD:1600115
G Kel Kell metallo-endopeptidase (Kell blood group) JBrowse link 4 70,979,504 70,996,920 RGD:1624291
G Klhl40 kelch-like family member 40 JBrowse link 8 130,416,265 130,421,871 RGD:1624291
RGD:13792537
G Klhl41 kelch-like family member 41 JBrowse link 3 55,910,177 55,923,303 RGD:1600115
G Lmod3 leiomodin 3 JBrowse link 4 129,604,378 129,619,136 RGD:1624291
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:1624291
RGD:1600115
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:1624291
G Myorg myogenesis regulating glycosidase JBrowse link 5 57,873,404 57,882,008 RGD:1624291
RGD:13792537
G Nfatc3 nuclear factor of activated T-cells 3 JBrowse link 19 38,039,542 38,114,003 RGD:1624291
G P2rx2 purinergic receptor P2X 2 JBrowse link 12 52,397,666 52,401,005 RGD:1624291
RGD:1600115
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1624291
G Rcan1 regulator of calcineurin 1 JBrowse link 11 32,539,689 32,620,274 RGD:1624291
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1600115
G Ryr1 ryanodine receptor 1 JBrowse link 1 87,959,596 88,066,252 RGD:1600115
RGD:1624291
G Selenon selenoprotein N JBrowse link 5 152,748,497 152,765,489 RGD:1624291
RGD:13792537
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:13792537
G Ski SKI proto-oncogene JBrowse link 5 172,556,196 172,623,878 RGD:1624291
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 7 70,807,427 70,815,271 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
G Xk X-linked Kx blood group JBrowse link X 14,497,376 14,534,479 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19335
    cellular process 17239
      cellular developmental process 4415
        cell development 2462
          muscle cell development 210
            striated muscle cell development 198
              muscle fiber development 77
                cardiac muscle fiber development + 13
                skeletal muscle fiber development + 39
Path 2
Term Annotations click to browse term
  biological_process 19335
    cellular process 17239
      cellular developmental process 4415
        cell differentiation 4195
          muscle cell differentiation 409
            striated muscle cell differentiation 331
              striated muscle cell development 198
                muscle fiber development 77
                  cardiac muscle fiber development + 13
                  skeletal muscle fiber development + 39
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.