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ONTOLOGY REPORT - ANNOTATIONS


Term:mesenchymal cell differentiation
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Accession:GO:0048762 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.


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mesenchymal cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1600115
RGD:1624291
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G LOC103690035 TGF-beta receptor type-1-like JBrowse link 5 64,565,358 64,585,219 RGD:1600115
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:12801486
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:729659
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1600115
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link 2 147,577,149 147,693,033 RGD:1624291
canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
cardiac endothelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
cardiac epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam15 ADAM metallopeptidase domain 15 JBrowse link 2 188,661,831 188,672,337 RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Heyl hes-related family bHLH transcription factor with YRPW motif-like JBrowse link 5 140,923,914 140,940,905 RGD:1624291
G LOC103690035 TGF-beta receptor type-1-like JBrowse link 5 64,565,358 64,585,219 RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Olfm1 olfactomedin 1 JBrowse link 3 6,761,031 6,798,739 RGD:1600115
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1600115
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Wnt16 Wnt family member 16 JBrowse link 4 49,369,246 49,388,156 RGD:1624291
G Wnt2 Wnt family member 2 JBrowse link 4 45,286,845 45,332,899 RGD:1624291
cardiac neural crest cell development involved in heart development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1624291
RGD:1600115
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
RGD:1600115
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
endocardial cushion to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvrl1 activin A receptor like type 1 JBrowse link 7 142,769,942 142,787,336 RGD:1624291
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Has2 hyaluronan synthase 2 JBrowse link 7 96,438,046 96,464,049 RGD:1624291
RGD:1600115
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
G Erg ETS transcription factor ERG JBrowse link 11 35,645,317 35,749,637 RGD:1624291
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akna AT-hook transcription factor JBrowse link 5 79,184,087 79,232,370 RGD:1624291
G Aknad1 AKNA domain containing 1 JBrowse link 2 211,541,800 211,585,332 RGD:1600115
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1600115
RGD:1624291
G Cul7 cullin 7 JBrowse link 9 16,629,491 16,643,527 RGD:1624291
RGD:1600115
G Ddx17 DEAD-box helicase 17 JBrowse link 7 120,761,843 120,765,012 RGD:1624291
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:1624291
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:1624291
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 13 35,622,472 35,673,449 RGD:1624291
G Fam83d family with sequence similarity 83, member D JBrowse link 3 155,269,344 155,288,612 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:632663
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:1624291
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1600115
RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B JBrowse link 10 34,955,713 34,961,662 RGD:1624291
RGD:1600115
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:13792537
RGD:1600115
G Lims1 LIM zinc finger domain containing 1 JBrowse link 20 27,895,981 28,004,767 RGD:1624291
G LOC103689931 heterogeneous nuclear ribonucleoprotein A/B JBrowse link 10 37,049,400 37,055,348 RGD:1600115
G Loxl2 lysyl oxidase-like 2 JBrowse link 15 51,276,022 51,365,238 RGD:1600115
RGD:1624291
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
G Nfatc1 nuclear factor of activated T-cells 1 JBrowse link 18 77,203,517 77,322,690 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Rflnb refilin B JBrowse link 10 64,196,103 64,202,380 RGD:1624291
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1302246
RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1578678
RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1600115
RGD:1624291
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:1624291
RGD:1600115
G Trip10 thyroid hormone receptor interactor 10 JBrowse link 9 9,689,214 9,702,353 RGD:11535143
G Wnt11 Wnt family member 11 JBrowse link 1 163,794,136 163,813,756 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
epithelial to mesenchymal transition involved in cardiac fibroblast development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:10400865
G Spry1 sprouty RTK signaling antagonist 1 JBrowse link 2 124,400,689 124,405,331 RGD:10400865
epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Heyl hes-related family bHLH transcription factor with YRPW motif-like JBrowse link 5 140,923,914 140,940,905 RGD:1624291
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Tmem100 transmembrane protein 100 JBrowse link 10 77,537,340 77,543,710 RGD:1624291
mesenchymal cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alx1 ALX homeobox 1 JBrowse link 7 44,751,865 44,771,458 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Heyl hes-related family bHLH transcription factor with YRPW motif-like JBrowse link 5 140,923,914 140,940,905 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
mesenchymal cell differentiation involved in bone development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ranbp3l RAN binding protein 3-like JBrowse link 2 58,221,773 58,458,072 RGD:1624291
mesenchymal cell differentiation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amer1 APC membrane recruitment protein 1 JBrowse link X 64,686,620 64,702,504 RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
mesenchymal cell differentiation involved in lung development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
mesenchymal cell differentiation involved in renal system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
mesodermal to mesenchymal transition involved in gastrulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
metanephric mesenchymal cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Tcf21 transcription factor 21 JBrowse link 1 23,906,717 23,909,576 RGD:1624291
RGD:1600115
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:1624291
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Dact3 dishevelled-binding antagonist of beta-catenin 3 JBrowse link 1 78,800,754 78,812,483 RGD:1624291
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
RGD:1600115
G Hpn hepsin JBrowse link 1 89,534,112 89,549,575 RGD:1600115
RGD:13792537
RGD:1624291
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 JBrowse link 18 63,717,423 64,045,224 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1600115
RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Pbld1 phenazine biosynthesis-like protein domain containing 1 JBrowse link 20 27,103,300 27,118,650 RGD:1624291
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 JBrowse link 1 226,543,671 226,572,414 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
G Strap serine/threonine kinase receptor associated protein JBrowse link 4 171,730,629 171,744,877 RGD:1624291
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Trim62 tripartite motif-containing 62 JBrowse link 5 147,068,725 147,099,024 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:11568680
G Usf3 upstream transcription factor family member 3 JBrowse link 11 61,427,140 61,499,668 RGD:1624291
G Vasn vasorin JBrowse link 10 11,121,041 11,131,548 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
negative regulation of neural crest formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fuz fuzzy planar cell polarity protein JBrowse link 1 100,891,832 100,896,811 RGD:1624291
RGD:1600115
neural crest cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:1624291
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:1624291
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 JBrowse link 1 256,369,410 256,380,649 RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1600115
RGD:1624291
G Fam172a family with sequence similarity 172, member A JBrowse link 2 4,942,795 5,547,744 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Kbtbd8 kelch repeat and BTB domain containing 8 JBrowse link 4 127,164,728 127,177,537 RGD:1600115
RGD:1624291
G Klhl12 kelch-like family member 12 JBrowse link 13 51,280,933 51,314,753 RGD:1600115
RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Nolc1 nucleolar and coiled-body phosphoprotein 1 JBrowse link 1 265,829,055 265,839,819 RGD:1624291
RGD:1600115
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pef1 penta-EF hand domain containing 1 JBrowse link 5 148,320,610 148,343,876 RGD:1624291
RGD:1600115
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Sox11 SRY-box transcription factor 11 JBrowse link 6 46,629,967 46,631,988 RGD:1624291
RGD:1600115
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:13792537
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Tcof1 treacle ribosome biogenesis factor 1 JBrowse link 18 56,081,863 56,115,719 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
neural crest cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1624291
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Wnt10a Wnt family member 10A JBrowse link 9 82,053,581 82,066,047 RGD:1624291
neural crest cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
RGD:1600115
neural crest cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gsc goosecoid homeobox JBrowse link 6 128,147,181 128,149,220 RGD:1624291
neural crest cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Alx1 ALX homeobox 1 JBrowse link 7 44,751,865 44,771,458 RGD:1600115
G Anxa6 annexin A6 JBrowse link 10 40,320,581 40,375,605 RGD:13792537
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:1624291
G Coro1c coronin 1C JBrowse link 12 48,481,741 48,554,054 RGD:1624291
RGD:13792537
G Edn3 endothelin 3 JBrowse link 3 172,856,730 172,879,276 RGD:1624291
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1624291
G Efnb1 ephrin B1 JBrowse link X 68,891,227 68,904,034 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Gbx2 gastrulation brain homeobox 2 JBrowse link 9 97,063,265 97,065,855 RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:1624291
G Lama5 laminin subunit alpha 5 JBrowse link 3 175,553,042 175,601,112 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Nrtn neurturin JBrowse link 9 10,299,881 10,306,599 RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:8552342
G Phactr4 phosphatase and actin regulator 4 JBrowse link 5 150,533,895 150,609,423 RGD:1624291
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:13792537
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:13792537
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
RGD:13792537
G Sema3d semaphorin 3D JBrowse link 4 19,224,378 19,413,519 RGD:13792537
G Sema3e semaphorin 3E JBrowse link 4 17,314,745 17,594,659 RGD:13792537
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
RGD:13792537
G Sema3g semaphorin 3G JBrowse link 16 7,303,582 7,315,214 RGD:13792537
G Sema4a semaphorin 4A JBrowse link 2 187,799,568 187,823,014 RGD:13792537
G Sema4b semaphorin 4B JBrowse link 1 141,986,145 142,014,400 RGD:13792537
G Sema4c semaphorin 4C JBrowse link 9 43,129,413 43,140,442 RGD:13792537
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:13792537
G Sema4f ssemaphorin 4F JBrowse link 4 113,738,225 113,764,532 RGD:13792537
G Sema4g semaphorin 4G JBrowse link 1 264,738,935 264,753,399 RGD:13792537
G Sema6a semaphorin 6A JBrowse link 18 41,330,519 41,451,813 RGD:13792537
G Sema6b semaphorin 6B JBrowse link 9 10,934,273 10,951,252 RGD:13792537
G Sema6c semaphorin 6C JBrowse link 2 196,330,777 196,347,218 RGD:13792537
G Sema6d semaphorin 6D JBrowse link 3 116,899,906 116,958,059 RGD:13792537
G Sema7a semaphorin 7A (John Milton Hagen blood group) JBrowse link 8 62,723,788 62,746,530 RGD:13792537
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Sox10 SRY-box transcription factor 10 JBrowse link 7 120,393,238 120,403,523 RGD:1624291
RGD:13792537
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:1624291
RGD:1600115
G Tbx1 T-box transcription factor 1 JBrowse link 11 86,552,022 86,561,647 RGD:1600115
RGD:1624291
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link 3 29,857,289 29,985,932 RGD:1624291
neural crest cell migration involved in autonomic nervous system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:1600115
RGD:1624291
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Phox2b paired-like homeobox 2b JBrowse link 14 42,711,169 42,718,707 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
neural crest cell migration involved in heart formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
neural crest cell migration involved in sympathetic nervous system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
neural crest formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kbtbd8 kelch repeat and BTB domain containing 8 JBrowse link 4 127,164,728 127,177,537 RGD:1600115
RGD:1624291
G Klhl12 kelch-like family member 12 JBrowse link 13 51,280,933 51,314,753 RGD:1600115
RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Nolc1 nucleolar and coiled-body phosphoprotein 1 JBrowse link 1 265,829,055 265,839,819 RGD:1624291
RGD:1600115
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pef1 penta-EF hand domain containing 1 JBrowse link 5 148,320,610 148,343,876 RGD:1624291
RGD:1600115
G Tcof1 treacle ribosome biogenesis factor 1 JBrowse link 18 56,081,863 56,115,719 RGD:1624291
positive regulation of cardiac endothelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata5 GATA binding protein 5 JBrowse link 3 175,701,278 175,709,465 RGD:1624291
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:13601997
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:13601997
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7243870
G Alx1 ALX homeobox 1 JBrowse link 7 44,751,865 44,771,458 RGD:1624291
RGD:1600115
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:1624291
RGD:1600115
G Bambi BMP and activin membrane-bound inhibitor JBrowse link 17 56,905,419 56,909,675 RGD:1624291
G Bcl9l BCL9 like JBrowse link 8 48,805,684 48,835,794 RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
G Crb2 crumbs cell polarity complex component 2 JBrowse link 3 22,037,812 22,061,247 RGD:1600115
RGD:1624291
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1600115
RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) JBrowse link 17 21,634,546 21,677,477 RGD:1624291
G Glipr2 GLI pathogenesis-related 2 JBrowse link 5 59,415,415 59,446,732 RGD:1624291
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590229
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:13210526
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1600115
RGD:1624291
G Loxl2 lysyl oxidase-like 2 JBrowse link 15 51,276,022 51,365,238 RGD:1600115
RGD:1624291
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:1600115
RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:13210526
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Olfm1 olfactomedin 1 JBrowse link 3 6,761,031 6,798,739 RGD:1600115
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1600115
RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1624291
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:1624291
RGD:1600115
G Serpinb3 serpin family B member 3 JBrowse link 13 27,186,701 27,193,211 RGD:1624291
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 JBrowse link 1 199,664,039 199,670,970 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1600115
RGD:1624291
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link 2 147,577,149 147,693,033 RGD:1624291
G Zfp703 zinc finger protein 703 JBrowse link 16 69,237,857 69,242,028 RGD:1624291
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
regulation of epithelial to mesenchymal transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clasp1 cytoplasmic linker associated protein 1 JBrowse link 13 34,365,038 34,584,651 RGD:1624291
G Clasp2 cytoplasmic linker associated protein 2 JBrowse link 8 122,003,719 122,185,495 RGD:1624291
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:1624291
G Ell3 elongation factor for RNA polymerase II 3 JBrowse link 3 113,400,395 113,405,869 RGD:1624291
RGD:1600115
G Epha3 Eph receptor A3 JBrowse link 11 421,253 783,037 RGD:1624291
RGD:1600115
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G LOC103690035 TGF-beta receptor type-1-like JBrowse link 5 64,565,358 64,585,219 RGD:1600115
G Mcrip1 MAPK regulated co-repressor interacting protein 1 JBrowse link 10 109,720,144 109,727,595 RGD:1624291
RGD:1600115
G Phldb1 pleckstrin homology-like domain, family B, member 1 JBrowse link 8 48,997,189 49,045,176 RGD:1600115
RGD:1624291
G Phldb2 pleckstrin homology-like domain, family B, member 2 JBrowse link 11 60,042,879 60,051,229 RGD:1624291
RGD:1600115
G Pofut2 protein O-fucosyltransferase 2 JBrowse link 20 12,117,811 12,128,747 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1600115
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:1624291
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
regulation of neural crest cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
regulation of neural crest cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
ventral trunk neural crest cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17240
      cellular developmental process 4415
        cell differentiation 4195
          mesenchymal cell differentiation 219
            cardiac endothelial to mesenchymal transition + 2
            epithelial to mesenchymal transition + 141
            mesenchymal cell development + 89
            mesenchymal cell differentiation involved in bone development 1
            mesenchymal cell differentiation involved in lung development 2
            mesenchymal cell differentiation involved in mammary gland development 0
            mesenchymal cell differentiation involved in renal system development + 6
            mesenchymal cell differentiation involved in salivary gland development 0
            mesenchymal cell fate commitment 0
            neural crest cell differentiation + 91
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            animal organ development 3898
              mesenchyme development 279
                mesenchymal cell differentiation 219
                  cardiac endothelial to mesenchymal transition + 2
                  epithelial to mesenchymal transition + 141
                  mesenchymal cell development + 89
                  mesenchymal cell differentiation involved in bone development 1
                  mesenchymal cell differentiation involved in lung development 2
                  mesenchymal cell differentiation involved in mammary gland development 0
                  mesenchymal cell differentiation involved in renal system development + 6
                  mesenchymal cell differentiation involved in salivary gland development 0
                  mesenchymal cell fate commitment 0
                  neural crest cell differentiation + 91
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.