ONTOLOGY REPORT - ANNOTATIONS


Term:calcium ion-regulated exocytosis of neurotransmitter
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Accession:GO:0048791 term browser browse the term
Definition:The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.


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calcium ion-regulated exocytosis of neurotransmitter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:1624291
RGD:1600115
G Doc2b double C2 domain beta JBrowse link 10 63,921,255 63,952,944 RGD:8554647
RGD:1624291
RGD:1600115
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
RGD:13792537
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:13792537
RGD:1600115
G Rims3 regulating synaptic membrane exocytosis 3 JBrowse link 5 139,790,395 139,819,014 RGD:13792537
G Rims4 regulating synaptic membrane exocytosis 4 JBrowse link 3 160,237,659 160,301,792 RGD:13792537
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:1581082
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1624291
RGD:1600115
G Syt1 synaptotagmin 1 JBrowse link 7 50,084,063 50,638,996 RGD:13792537
RGD:1624291
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:13792537
G Syt17 synaptotagmin 17 JBrowse link 1 188,034,614 188,101,590 RGD:13792537
G Syt2 synaptotagmin 2 JBrowse link 13 51,569,248 51,577,824 RGD:13792537
G Syt4 synaptotagmin 4 JBrowse link 18 24,172,580 24,181,989 RGD:13792537
G Syt5 synaptotagmin 5 JBrowse link 1 72,859,806 72,867,934 RGD:13792537
G Syt7 synaptotagmin 7 JBrowse link 1 226,435,816 226,498,008 RGD:1624291
RGD:13792537
RGD:1600115
G Syt8 synaptotagmin 8 JBrowse link 1 215,605,408 215,607,602 RGD:13792537
fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syt1 synaptotagmin 1 JBrowse link 7 50,084,063 50,638,996 RGD:1600115
RGD:1624291
positive regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Syt1 synaptotagmin 1 JBrowse link 7 50,084,063 50,638,996 RGD:1600115
RGD:1624291
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadps calcium dependent secretion activator JBrowse link 15 15,275,489 15,690,575 RGD:1600115
RGD:1624291
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:1624291
RGD:1600115
G Syt6 synaptotagmin 6 JBrowse link 2 206,064,181 206,119,034 RGD:13702162
G Unc13a unc-13 homolog A JBrowse link 16 20,056,398 20,103,951 RGD:1600115
RGD:13792537
RGD:1624291
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:1624291
RGD:13792537
G Unc13c unc-13 homolog C JBrowse link 8 80,202,736 80,656,363 RGD:13792537
regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:1624291
RGD:1600115
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1624291
RGD:1600115
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:13702177
G Syt4 synaptotagmin 4 JBrowse link 18 24,172,580 24,181,989 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    localization 5991
      cellular localization 2664
        establishment of localization in cell 1970
          synaptic vesicle exocytosis 156
            calcium ion-regulated exocytosis of neurotransmitter 25
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
              negative regulation of calcium ion-dependent exocytosis of neurotransmitter 0
              positive regulation of calcium ion-dependent exocytosis of neurotransmitter 1
              presynaptic dense core vesicle exocytosis + 8
              regulation of calcium ion-dependent exocytosis of neurotransmitter + 5
              slow, calcium ion-dependent exocytosis of neurotransmitter 0
Path 2
Term Annotations click to browse term
  biological_process 17926
    localization 5991
      establishment of localization 4600
        transport 4460
          secretion 1303
            secretion by cell 1112
              signal release 552
                signal release from synapse 206
                  neurotransmitter secretion 206
                    synaptic vesicle exocytosis 156
                      calcium ion-regulated exocytosis of neurotransmitter 25
                        fast, calcium ion-dependent exocytosis of neurotransmitter 1
                        negative regulation of calcium ion-dependent exocytosis of neurotransmitter 0
                        positive regulation of calcium ion-dependent exocytosis of neurotransmitter 1
                        presynaptic dense core vesicle exocytosis + 8
                        regulation of calcium ion-dependent exocytosis of neurotransmitter + 5
                        slow, calcium ion-dependent exocytosis of neurotransmitter 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.