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ONTOLOGY REPORT - ANNOTATIONS


Term:hydrogen peroxide biosynthetic process
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Accession:GO:0050665 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms:exact_synonym: H2O2 biosynthetic process;   hydrogen peroxide anabolism;   hydrogen peroxide biosynthesis;   hydrogen peroxide formation;   hydrogen peroxide generation;   hydrogen peroxide synthesis


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hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:2317869
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:1624291
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:1624291
G Duox1 dual oxidase 1 JBrowse link 3 114,251,794 114,286,827 RGD:1600115
RGD:1624291
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1600115
RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1581090
RGD:1600115
RGD:1624291
RGD:1601266
RGD:634854
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:2291946
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctns cystinosin, lysosomal cystine transporter JBrowse link 10 59,749,250 59,772,475 RGD:12910938
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:7349317
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:13601987
G Mpv17l MPV17 mitochondrial inner membrane protein like JBrowse link 10 3,321,488 3,359,219 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694322
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 3 114,236,718 114,240,086 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:13506652
G Zfp13 zinc finger protein 13 JBrowse link 10 12,908,643 12,916,784 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      biosynthetic process 5933
        reactive oxygen species biosynthetic process 130
          hydrogen peroxide biosynthetic process 19
            negative regulation of hydrogen peroxide biosynthetic process 5
            positive regulation of hydrogen peroxide biosynthetic process 5
            regulation of hydrogen peroxide biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 19336
    cellular process 17240
      cellular metabolic process 10567
        drug metabolic process 584
          antibiotic metabolic process 129
            antibiotic biosynthetic process 24
              hydrogen peroxide biosynthetic process 19
                negative regulation of hydrogen peroxide biosynthetic process 5
                positive regulation of hydrogen peroxide biosynthetic process 5
                regulation of hydrogen peroxide biosynthetic process + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.