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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-1 beta secretion
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Accession:GO:0050702 term browser browse the term
Definition:The regulated release of interleukin 1 beta from a cell.
Synonyms:exact_synonym: IL-1b secretion


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interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 JBrowse link 4 53,030,789 53,159,988 RGD:2290270
G Aim2 absent in melanoma 2 JBrowse link 1 173,349,547 173,466,040 RGD:2290270
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:2290270
G F2rl1 coagulation factor II (thrombin) receptor-like 1 JBrowse link 13 95,511,718 95,525,240 RGD:2290270
G Gbp5 guanylate binding protein 5 JBrowse link 3 142,496,934 142,522,344 RGD:2290270
G Nlrc4 NLR family, CARD domain containing 4 JBrowse link 17 74,426,255 74,459,144 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Tlr6 toll-like receptor 6 JBrowse link 5 64,952,030 64,970,942 RGD:2290270
G Tmem106a transmembrane protein 106A JBrowse link 11 101,582,242 101,591,788 RGD:2290270
negative regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A-I JBrowse link 9 46,228,630 46,230,469 RGD:2290270
G Cptp ceramide-1-phosphate transfer protein JBrowse link 4 155,864,723 155,869,440 RGD:2290270
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 11 59,541,569 59,566,955 RGD:2290270
G Pml promyelocytic leukemia JBrowse link 9 58,217,179 58,249,796 RGD:2290270
G Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a JBrowse link 13 32,842,092 32,853,206 RGD:2290270
G Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b JBrowse link 13 33,078,504 33,094,380 RGD:2290270
G Serpinb1c serine (or cysteine) peptidase inhibitor, clade B, member 1c JBrowse link 13 32,881,350 32,940,628 RGD:2290270
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 JBrowse link 10 19,000,910 19,015,410 RGD:2290270
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 4 125,118,414 125,127,881 RGD:2290270
positive regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aim2 absent in melanoma 2 JBrowse link 1 173,349,547 173,466,040 RGD:2290270
G Casp1 caspase 1 JBrowse link 9 5,298,517 5,307,281 RGD:2290270
G Casp4 caspase 4, apoptosis-related cysteine peptidase JBrowse link 9 5,308,823 5,336,791 RGD:2290270
G Ccl19 chemokine (C-C motif) ligand 19 JBrowse link 4 42,754,525 42,756,518 RGD:2290270
G Ccl3 chemokine (C-C motif) ligand 3 JBrowse link 11 83,647,843 83,649,378 RGD:2290270
G Ccr5 chemokine (C-C motif) receptor 5 JBrowse link 9 124,121,543 124,127,183 RGD:2290270
G Ccr7 chemokine (C-C motif) receptor 7 JBrowse link 11 99,144,199 99,155,077 RGD:2290270
G Fzd5 frizzled class receptor 5 JBrowse link 1 64,730,558 64,737,750 RGD:2290270
G Gsdmd gasdermin D JBrowse link 15 75,862,144 75,867,408 RGD:2290270
G Hk1 hexokinase 1 JBrowse link 10 62,268,855 62,379,920 RGD:2290270
G Hmgb1 high mobility group box 1 JBrowse link 5 149,046,702 149,053,057 RGD:2290270
G Hmgb4 high-mobility group box 4 JBrowse link 4 128,260,212 128,260,895 RGD:2290270
G Ifnar1 interferon (alpha and beta) receptor 1 JBrowse link 16 91,485,032 91,510,523 RGD:2290270
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:2290270
G Lilra5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 JBrowse link 7 4,237,643 4,243,690 RGD:2290270
G Lpl lipoprotein lipase JBrowse link 8 68,880,555 68,906,932 RGD:2290270
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 11 71,091,197 71,144,969 RGD:2290270
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 11 71,152,574 71,242,514 RGD:2290270
G Nlrp2 NLR family, pyrin domain containing 2 JBrowse link 7 5,298,547 5,351,035 RGD:2290270
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 11 59,541,569 59,566,955 RGD:2290270
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 8 88,647,315 88,688,474 RGD:2290270
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 JBrowse link 5 122,643,927 122,692,336 RGD:2290270
G Panx1 pannexin 1 JBrowse link 9 15,005,785 15,045,478 RGD:2290270
G Pycard PYD and CARD domain containing JBrowse link 7 127,991,373 127,993,867 RGD:2290270
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 JBrowse link 4 16,122,732 16,163,678 RGD:2290270
G Tlr2 toll-like receptor 2 JBrowse link 3 83,836,272 83,841,824 RGD:2290270
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:2290270
G Tlr8 toll-like receptor 8 JBrowse link X 167,241,123 167,264,329 RGD:2290270
G Trim16 tripartite motif-containing 16 JBrowse link 11 62,820,198 62,842,948 RGD:2290270
G Usp50 ubiquitin specific peptidase 50 JBrowse link 2 126,761,050 126,783,460 RGD:2290270
G Wnt5a wingless-type MMTV integration site family, member 5A JBrowse link 14 28,504,543 28,527,448 RGD:2290270
regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase type II JBrowse link 12 79,130,788 79,156,301 RGD:2290270
G Ccr7 chemokine (C-C motif) receptor 7 JBrowse link 11 99,144,199 99,155,077 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23109
    multicellular organismal process 8254
      cytokine production 762
        interleukin-1 production 104
          interleukin-1 beta production 86
            interleukin-1 beta secretion 47
              negative regulation of interleukin-1 beta secretion 9
              positive regulation of interleukin-1 beta secretion 31
              regulation of interleukin-1 beta secretion + 40
Path 2
Term Annotations click to browse term
  biological_process 23109
    localization 6027
      establishment of localization 4609
        transport 4473
          nitrogen compound transport 2204
            amide transport 1894
              peptide transport 1869
                protein transport 1817
                  protein secretion 614
                    cytokine secretion 247
                      interleukin-1 secretion 55
                        interleukin-1 beta secretion 47
                          negative regulation of interleukin-1 beta secretion 9
                          positive regulation of interleukin-1 beta secretion 31
                          regulation of interleukin-1 beta secretion + 40
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.