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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-1 secretion
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Accession:GO:0050711 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell.
Synonyms:exact_synonym: down regulation of interleukin-1 secretion;   downregulation of interleukin-1 secretion
 narrow_synonym: inhibition of interleukin-1 secretion


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negative regulation of interleukin-1 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
negative regulation of interleukin-1 alpha secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:1624291
RGD:1600115
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10043380
negative regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:1600115
G Cptp ceramide-1-phosphate transfer protein JBrowse link 5 173,314,219 173,318,384 RGD:1600115
RGD:1624291
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Serpinb1a serpin family B member 1A JBrowse link 17 32,903,089 32,911,498 RGD:1600115
RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1600115
RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    multicellular organismal process 8629
      cytokine production 781
        negative regulation of cytokine production 270
          negative regulation of interleukin-1 production 30
            negative regulation of interleukin-1 secretion 12
              negative regulation of interleukin-1 alpha secretion 2
              negative regulation of interleukin-1 beta secretion 8
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                peptide secretion 687
                  protein secretion 634
                    cytokine secretion 260
                      interleukin-1 secretion 64
                        regulation of interleukin-1 secretion 56
                          negative regulation of interleukin-1 secretion 12
                            negative regulation of interleukin-1 alpha secretion 2
                            negative regulation of interleukin-1 beta secretion 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.