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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of peptidyl-tyrosine phosphorylation
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Accession:GO:0050732 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
Synonyms:exact_synonym: down regulation of peptidyl-tyrosine phosphorylation;   downregulation of peptidyl-tyrosine phosphorylation
 narrow_synonym: inhibition of peptidyl-tyrosine phosphorylation


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negative regulation of peptidyl-tyrosine phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm4 cell adhesion molecule 4 JBrowse link 1 81,365,200 81,369,841 RGD:1600115
RGD:1624291
G Dmtn dematin actin binding protein JBrowse link 15 52,292,762 52,320,385 RGD:1624291
RGD:1600115
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655996
G Lrrk1 leucine-rich repeat kinase 1 JBrowse link 1 127,166,866 127,301,053 RGD:1624291
RGD:1600115
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:1624291
RGD:1600115
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:7240703
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 JBrowse link 11 14,252,088 14,405,825 RGD:1624291
RGD:13792537
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:1624291
RGD:1600115
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
RGD:1600115
G Spink1 serine peptidase inhibitor, Kazal type 1 JBrowse link 18 38,221,919 38,242,092 RGD:1624291
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1625011
negative regulation of brain-derived neurotrophic factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam72a family with sequence similarity 72, member A JBrowse link 13 48,288,071 48,298,604 RGD:8553945
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:13792537
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:13792537
G Cblc Cbl proto-oncogene C JBrowse link 1 80,699,321 80,716,146 RGD:1624291
RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
RGD:1600115
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:8553726
RGD:1600115
RGD:1624291
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
RGD:1600115
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:1624291
RGD:1600115
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
RGD:1600115
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
RGD:1600115
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
RGD:1600115
G Zfyve28 zinc finger FYVE-type containing 28 JBrowse link 14 81,725,513 81,811,142 RGD:1624291
RGD:13792537
G Zgpat zinc finger CCCH-type and G-patch domain containing JBrowse link 3 176,865,078 176,881,603 RGD:1624291
RGD:1600115
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1600115
RGD:1624291
negative regulation of peptidyl-tyrosine autophosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:13792537
RGD:1600115
G Fgfr1op Fgfr1 oncogene partner JBrowse link 1 53,122,330 53,152,872 RGD:1600115
G Ggnbp2 gametogenetin binding protein 2 JBrowse link 10 72,156,729 72,188,834 RGD:1624291
RGD:1600115
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Ibtk inhibitor of Bruton tyrosine kinase JBrowse link 8 93,323,454 93,397,044 RGD:1600115
G Mvp major vault protein JBrowse link 1 198,420,813 198,448,612 RGD:1600115
RGD:1624291
G Ptk6 protein tyrosine kinase 6 JBrowse link 3 176,698,305 176,706,896 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1600115
G Sh3bp5 SH3-domain binding protein 5 JBrowse link 16 7,473,367 7,559,976 RGD:13792537
G Sh3bp5l SH3 binding domain protein 5 like JBrowse link 10 43,768,620 43,785,702 RGD:13792537
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1624291
RGD:1600115
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:12793046
negative regulation of tyrosine phosphorylation of STAT protein term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ggnbp2 gametogenetin binding protein 2 JBrowse link 10 72,156,729 72,188,834 RGD:1624291
RGD:1600115
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1625011
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:1624291
RGD:1600115
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:5128774
G Nf2 neurofibromin 2 JBrowse link 14 84,996,905 85,088,547 RGD:1600115
RGD:1624291
G Parp14 poly (ADP-ribose) polymerase family, member 14 JBrowse link 11 68,105,442 68,137,509 RGD:1624291
RGD:1600115
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Sh2b3 SH2B adaptor protein 3 JBrowse link 12 40,261,990 40,265,757 RGD:1624291
RGD:1600115
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1624291
RGD:1600115
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:1600115
RGD:1624291
G Suz12 SUZ12 polycomb repressive complex 2 subunit JBrowse link 10 67,325,101 67,371,588 RGD:9586745

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      negative regulation of metabolic process 3065
        negative regulation of cellular metabolic process 2686
          negative regulation of cellular protein metabolic process 1111
            negative regulation of protein modification process 624
              negative regulation of protein phosphorylation 429
                negative regulation of peptidyl-tyrosine phosphorylation 57
                  negative regulation of activation of Janus kinase activity 2
                  negative regulation of peptidyl-tyrosine autophosphorylation 1
                  negative regulation of protein tyrosine kinase activity + 31
                  negative regulation of tyrosine phosphorylation of STAT protein 13
Path 2
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      organic substance metabolic process 10932
        macromolecule metabolic process 9412
          protein metabolic process 5975
            protein modification process 3864
              cellular protein modification process 3864
                peptidyl-amino acid modification 1278
                  peptidyl-tyrosine modification 390
                    peptidyl-tyrosine phosphorylation 387
                      regulation of peptidyl-tyrosine phosphorylation 276
                        negative regulation of peptidyl-tyrosine phosphorylation 57
                          negative regulation of activation of Janus kinase activity 2
                          negative regulation of peptidyl-tyrosine autophosphorylation 1
                          negative regulation of protein tyrosine kinase activity + 31
                          negative regulation of tyrosine phosphorylation of STAT protein 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.