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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of immune response
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Accession:GO:0050777 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
Synonyms:exact_synonym: down regulation of immune response;   downregulation of immune response
 narrow_synonym: inhibition of immune response


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negative regulation of immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:1624291
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:2302005
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Fcrlb Fc receptor-like B JBrowse link 13 89,284,801 89,293,266 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:2325989
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Nlrp6 NLR family, pyrin domain containing 6 JBrowse link 1 213,676,954 213,683,114 RGD:1624291
G Olfm4 olfactomedin 4 JBrowse link 15 62,384,263 62,429,450 RGD:1624291
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:730199
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:730199
negative regulation of activation of membrane attack complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1600482
RGD:13792537
RGD:1624291
negative regulation of acute inflammatory response to antigenic stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325282
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448932
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:10448932
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1624291
RGD:1600115
negative regulation of adaptive immune memory response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
G Tnfrsf14 TNF receptor superfamily member 14 JBrowse link 5 172,328,259 172,337,221 RGD:1624291
negative regulation of adaptive immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 JBrowse link 11 14,252,088 14,405,825 RGD:1624291
G Trim27 tripartite motif-containing 27 JBrowse link 17 45,613,863 45,626,212 RGD:1624291
negative regulation of antibacterial peptide production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spink5 serine peptidase inhibitor, Kazal type 5 JBrowse link 18 35,118,300 35,190,458 RGD:1624291
negative regulation of antifungal innate immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam3a FAM3 metabolism regulating signaling molecule A JBrowse link X 156,319,687 156,328,974 RGD:1624291
negative regulation of chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
negative regulation of complement activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:2293559
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:2326180
RGD:1624291
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1624291
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:625470
RGD:1624291
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:1624291
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,370,851 65,400,298 RGD:1624291
RGD:13792537
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1624291
RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:1624291
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:1624291
RGD:1600115
negative regulation of cytokine secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1624291
RGD:1600115
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
negative regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
negative regulation of germinal center formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
negative regulation of immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
negative regulation of inflammatory response to antigenic stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Gpr17 G protein-coupled receptor 17 JBrowse link 18 24,733,306 24,739,194 RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Gpx2 glutathione peroxidase 2 JBrowse link 6 99,839,960 99,843,245 RGD:1624291
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Nlrp6 NLR family, pyrin domain containing 6 JBrowse link 1 213,676,954 213,683,114 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Psma1 proteasome 20S subunit alpha 1 JBrowse link 1 183,733,567 183,744,586 RGD:1624291
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:1600115
RGD:1624291
negative regulation of innate immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
G Dhx58 DEXH-box helicase 58 JBrowse link 10 88,599,722 88,611,562 RGD:1624291
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 5 156,855,105 156,864,517 RGD:1624291
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Nlrx1 NLR family member X1 JBrowse link 8 48,583,559 48,600,203 RGD:1624291
RGD:1600115
G Nmi N-myc (and STAT) interactor JBrowse link 3 37,458,891 37,480,984 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Trafd1 TRAF type zinc finger domain containing 1 JBrowse link 12 40,695,520 40,709,438 RGD:1600115
RGD:1624291
G Tyro3 TYRO3 protein tyrosine kinase JBrowse link 3 111,597,102 111,616,142 RGD:1600115
RGD:1624291
negative regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Otop1 otopetrin 1 JBrowse link 14 77,236,278 77,263,729 RGD:1600115
RGD:1624291
G Parp14 poly (ADP-ribose) polymerase family, member 14 JBrowse link 11 68,105,442 68,137,509 RGD:1624291
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
negative regulation of macrophage cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cuedc2 CUE domain containing 2 JBrowse link 1 266,078,107 266,087,057 RGD:1624291
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
negative regulation of mast cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1600115
RGD:1624291
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1600115
RGD:1624291
negative regulation of mast cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601626
negative regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601626
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgl2 fibrinogen-like 2 JBrowse link 4 10,323,598 10,329,241 RGD:1624291
G Ifnl1 interferon, lambda 1 JBrowse link 1 85,252,103 85,253,635 RGD:1624291
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd96 CD96 molecule JBrowse link 11 57,108,757 57,183,855 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pglyrp1 peptidoglycan recognition protein 1 JBrowse link 1 79,790,879 79,796,064 RGD:1624291
RGD:1600115
G Pglyrp2 peptidoglycan recognition protein 2 JBrowse link 7 14,426,481 14,435,987 RGD:1624291
G Pglyrp3 peptidoglycan recognition protein 3 JBrowse link 2 191,903,626 192,264,872 RGD:1624291
G Pglyrp4 peptidoglycan recognition protein 4 JBrowse link 2 190,125,655 190,204,230 RGD:1624291
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
G Clec12b C-type lectin domain family 12, member B JBrowse link 4 163,140,883 163,157,996 RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:11568650
G Gfer growth factor, augmenter of liver regeneration JBrowse link 10 14,059,347 14,061,703 RGD:9685777
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:9685777
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313500
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
G Sh2d1b2 SH2 domain containing 1B2 JBrowse link 13 88,557,361 88,584,078 RGD:1624291
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Klre1 killer cell lectin-like receptor, family E, member 1 JBrowse link 4 163,346,684 163,355,050 RGD:1299590
negative regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 16 19,938,781 19,942,353 RGD:1624291
RGD:1600115
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp10 dual specificity phosphatase 10 JBrowse link 13 104,284,660 104,321,455 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Rps19 ribosomal protein S19 JBrowse link 1 81,750,873 81,756,629 RGD:1624291
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:1624291
negative regulation of T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1600115
negative regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Il7r interleukin 7 receptor RGD:1624291
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
RGD:1600115
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:2303754
negative regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec4g C-type lectin domain family 4, member G JBrowse link 12 2,273,649 2,278,594 RGD:1624291
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of T-helper 1 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:1624291
RGD:1600115
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
negative regulation of T-helper 17 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1624291
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
G Zfp35 zinc finger protein 35 JBrowse link 18 15,883,182 15,898,803 RGD:1624291
negative regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
negative regulation of type 2 immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
G Ifnl1 interferon, lambda 1 JBrowse link 1 85,252,103 85,253,635 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
G Zfp35 zinc finger protein 35 JBrowse link 18 15,883,182 15,898,803 RGD:1624291
negative regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:1624291
RGD:1600115
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Dcst1 DC-STAMP domain containing 1 JBrowse link 2 188,672,549 188,690,004 RGD:1624291
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:1600115
RGD:1624291
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 5 156,855,105 156,864,517 RGD:1624291
G Nlrc5 NLR family, CARD domain containing 5 JBrowse link 19 10,904,381 11,006,202 RGD:1624291
RGD:13792537
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 JBrowse link 3 153,210,829 153,250,705 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
G Ttll12 tubulin tyrosine ligase like 12 JBrowse link 7 124,472,758 124,491,004 RGD:1624291
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 JBrowse link 2 100,677,388 100,711,365 RGD:1624291
negative regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1624291
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec2d C-type lectin domain family 2, member D JBrowse link 4 162,278,252 162,302,881 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
G Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A JBrowse link 13 27,153,500 27,159,319 RGD:1624291
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:2312378
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:2312378

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    negative regulation of biological process 5553
      negative regulation of immune system process 487
        negative regulation of immune response 163
          negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response 0
          negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
          negative regulation of T-helper cell differentiation + 19
          negative regulation of adaptive immune response + 52
          negative regulation of basophil degranulation 0
          negative regulation of cytokine production involved in immune response + 25
          negative regulation of eosinophil degranulation 1
          negative regulation of gamma-delta T cell activation involved in immune response 0
          negative regulation of humoral immune response + 15
          negative regulation of immune response to tumor cell + 4
          negative regulation of inflammatory response to antigenic stimulus + 16
          negative regulation of innate immune response + 60
          negative regulation of mast cell activation involved in immune response + 9
          negative regulation of memory T cell differentiation 2
          negative regulation of natural killer cell differentiation involved in immune response 4
          negative regulation of natural killer cell proliferation involved in immune response 0
          negative regulation of neutrophil degranulation 2
          negative regulation of plasma cell differentiation 0
          negative regulation of type 2 immune response + 14
Path 2
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of biological process 12651
        negative regulation of biological process 5553
          negative regulation of response to stimulus 1633
            negative regulation of immune response 163
              negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response 0
              negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
              negative regulation of T-helper cell differentiation + 19
              negative regulation of adaptive immune response + 52
              negative regulation of basophil degranulation 0
              negative regulation of cytokine production involved in immune response + 25
              negative regulation of eosinophil degranulation 1
              negative regulation of gamma-delta T cell activation involved in immune response 0
              negative regulation of humoral immune response + 15
              negative regulation of immune response to tumor cell + 4
              negative regulation of inflammatory response to antigenic stimulus + 16
              negative regulation of innate immune response + 60
              negative regulation of mast cell activation involved in immune response + 9
              negative regulation of memory T cell differentiation 2
              negative regulation of natural killer cell differentiation involved in immune response 4
              negative regulation of natural killer cell proliferation involved in immune response 0
              negative regulation of neutrophil degranulation 2
              negative regulation of plasma cell differentiation 0
              negative regulation of type 2 immune response + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.